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La forte augmentation des taux de surpoids et d’obésité1 constitue une menace pour la santé de milliards
de personnes dans le monde. En 2016, plus de 1,9 milliard d’adultes âgés de 18 ans ou plus étaient en surpoid
This publication aims to provide updated guidance on the specific use of yellow fever laboratory assays in the context of surveillance to be used across the Global Yellow Fever Laboratory Network for disease surveillance. In the recent years, new commercial assays became available and are now recomm
...
ended for use by WHO and this publication will support national program on the use of compound laboratory assays as per the most recent recommended testing algorithms. This piece is aligned with the elimination effort set in the comprehensive global strategy to eliminate yellow fever epidemics (EYE) strategy 2017-2026 and where its advisory laboratory technical working group actively contributed to its development. The target audiences are policy-makers and health workers.
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Polio Bulletin
2024 Issue No. 1 - Week 1 (as of 2 January 2024)
Preliminary data from Member States indicate that the number of cholera cases reported in 2023 as of 15 December has surpassed that of 2022, with over 667 000 cases and 4000 deaths. These figures must be interpreted with caution given the varying surveillance systems and capacity across countries, w
...
hich means that 2023 data are not directly comparable to reports from previous years.
more
The pathway to strengthen multisectoral collaboration at the human-animal-environmental interface (HAI) aims to improve health security through One Health implementation. It outlines strategic
...
guides and tools developed to support Member States through different steps of the HAI pathway.
more
Fires, explosions and volcanic eruptions can damage and contaminate food and water due to heat, smoke, fumes and chemicals. These flyers include tips to reduce food safety risks during a fire incident for households, food suppliers, vendors, food industry inspectors and workers.
After a flood, food that has been in contact with flood-water may have become unsafe for human consumption. These flyers include tips to reduce food safety risks in the event of a flood for households,
Natural disasters and emergencies frequently cause power outages that can compromise the quality and safety of food. These flyers include tips to reduce food safety risks during a power outage for households, food suppliers, vendors, food industry inspectors and workers.
Postnatal care is essential for all women, their babies, and families during the first few weeks after birth.
Yet, coverage and quality of postnatal care remains suboptimal. We invite those who advocate for improved
...
health and health service experiences for women, newborns, parents, and families to join efforts for increasing the quality of postnatal care, so that every woman and every newborn receives the care they need to survive and thrive.
more
Advanced HIV disease (defined in persons living with HIV with a CD4 cell count of <200cells/mm3 or presenting with a WHO Stage 3/4 AIDS-defining illness) poses a challenge to many countries globally and is responsible for significant mortality and m
...
orbidity among people living with HIV. In 2017, WHO recommended a package of care for the prevention and management of advanced HIV disease. The package was composed of screening tests, diagnostics, prophylaxis, rapid antiretroviral therarpy initiation and enhanced adherence counselling.
more
This document provides detailed guidance on laboratory testing for suspected diphtheria cases during significant outbreaks or in low-resource settings. It aims to supplement and build on other existing WHO guidance documents on surveillance standard
...
s, diagnostics and research on Corynebacterium by providing key considerations for laboratories that allow the rationalization and optimization of testing during outbreaks. The recommendations given here have been prepared by WHO in consultation with, and reviewed by, global experts with experience in laboratory analysis of Corynebacterium species and in outbreak settings, or with expertise in developing new technologies for diphtheria research and diagnosis. Unless otherwise stated, the considerations provided apply to diphtheria outbreaks caused by toxin-producing C. diphtheriae with a classical respiratory diphtheria presentation.
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Las escuelas juegan un papel fundamental a la hora de crear entornos seguros y enriquecedores que aseguren a los estudiantes los cimientos para desarrollarse, aprender y convertirse en ciudadanos sanos, instruidos y comprometidos
De juin jusqu’en fin du mois de novembre 2023, le Tchad a été le pays africain le plus affecté par le conflit armé au Soudan, accueillant 47,9 % des réfugiés Soudanais. Ces derniers, ainsi que des retournés Tchadiens, sont arrivés dans les provinces du Ouaddaï, Sila, Wadi-Fira et de l’E
...
nnedi- Est. Au 26 novembre 2023, les provinces de l'est dénombraient un total de 451 894 réfugiés soudanais (dont 51,2 % sont à Adré, épicentre de la crise) et 99 513 retournés tchadiens depuis le début du conflit. On dénombre également 4 296 blessés pris en charge avec le soutien de MSF-France, PUI, Alima, la Croix-Rouge et une Équipe Médicale d'Urgence Internationale déployée par l'Organisation mondiale de la Santé (OMS).
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Antimicrobial resistance (AMR) is impacting our health, economies and development. Up to 5.2 million people may die because of resistant bacterial infections across the Western Pacific Region from 2020-2030. Childbirth, surgery, cancer treatme
...
nt and other interventions will become impossibly dangerous if bacterial infections no longer respond to available antibiotics.
more
Food inspection is crucial for ensuring food safety, using risk-based approaches to target high-risk products and businesses. This guidance aids national authorities in designing and implementing risk-based systems, offering step-by-step instructions, examples, and tools for prioritization and inspe
...
ction frequency estimation. It emphasizes adapting to individual country needs and recognizing variations in food risks and production chain characteristics. The document underscores resource-efficient, risk-based food inspection systems, prioritizing high-risk products and businesses to prevent safety incidents proactively. It suggests designing models based on relevant information and periodically adjusting them for continuous improvement.
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Laboratory manual for yellow fever
recommended
This WHO laboratory manual provides the most up to date methods and procedures for the laboratory identification of yellow fever virus infection in humans. It provides guidance on the establishment and maintenance of an effective laboratory providin
...
g routine surveillance testing for yellow fever, which operates within the WHO coordinated Global Yellow Fever Laboratory Network (GYFLaN) capable of providing confirmation of yellow fever infection reliably and timely. This second edition supersedes the first edition of the 2004 WHO manual for the monitoring of yellow fever virus infection.
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WHO has published the first-ever guidance on the clinical management of diphtheria. The only previously available guidance was an operational protocol. The new guidance followed the rigorous process for developing guidance at
...
WHO.
It addresses the use of Diphtheria Antitoxin (DAT) in the treatment of diphtheria. There is a worldwide shortage of DAT and evidence based recommendations on the use of DAT were requested by many Member States.
The guidance also includes new recommendations on antibiotics. In patients with suspected or confirmed diphtheria, WHO recommends using macrolide antibiotics (azithromycin, erythromycin) rather than penicillin antibiotics.
This clinical practice guideline has been rapidly developed recognizing the global increase in diphtheria outbreaks. Outbreaks of diphtheria in Nigeria, Guinea and neighbouring countries in 2023 have highlighted the urgent need for evidence-based clinical practice guidelines for the treatment of diphtheria. Given the sporadic nature of outbreaks, many clinicians in the affected regions have never managed acute diphtheria and its related complications. Diphtheria remains a neglected disease and vaccination is the top priority. At the same time, for patients with diphtheria, access to antibiotics, DAT and supportive care can be lifesaving.
more
A sanitary inspection is a simple, on-site evaluation (traditionally using a checklist) to help identify and support the management of priority risk factors that may lead to contamination of a drinking-water supply. Sanitary inspections are a well-established and widely-applied practice. They can su
...
pport water safety planning, and in some contexts, may be a simplified alternative to water safety plans.
This publication presents the World Health Organization’s (WHO’s) sanitary inspection packages. These packages update the sanitary inspection forms in WHO’s 1997 Guidelines for drinking-water quality. Volume 3: surveillance and control of community supplies. With more than 25 years of practical experience with the application of sanitary inspections, these packages have been developed from a comprehensive evidence review and established good practices.
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Diphtheria is caused by Corynebacterium species, mostly by toxin-producing Corynebacterium diphtheriae and rarely by toxin-producing strains of C. ulcerans and C. pseudotuberculosis. The most common type of diphtheria is classic respiratory diphtheria, whereby the exotoxin produced characteristicall
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y causes the formation of a pseudomembrane in the upper respiratory tract and damages other organs, usually the myocardium and peripheral nerves. Acute respiratory obstruction, acute systemic toxicity, myocarditis and neurologic complications are the usual causes of death. The infection can also affect the skin (cutaneous diphtheria). More rarely, it can affect mucous membranes at other non-respiratory sites, such as genitalia and conjunctiva.
C. diphtheriae is transmitted from person to person by intimate respiratory and direct contact; in contrast, C. ulcerans and C. pseudotuberculosis are zoonotic infections, not transmitted person-to-person. The incubation period of C. diphtheriae is two to five days (range 1– 10 days). A person is infectious as long as virulent bacteria are present in respiratory secretions, usually two weeks without antibiotics, and seldom more than six weeks. In rare cases, chronic carriers may shed organisms for six months or more. Skin lesions are often chronic and infectious for longer periods. Effective antibiotic therapy (penicillin or erythromycin) promptly terminates shedding in about one or two days.
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