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International Journal for Parasitology: Drugs and Drug Resistance Volume 28, August 2025, 100602
This review provides innovative insights to circumvent antimalarial drug resistance and diversify malaria therapeutics.
The 2025 Impact Report summarises Malaria Consortium's year in numbers and includes a message from the Chief Executive.
The GHEC framework is designed to provide guiding principles for standardizing health emergency workforce structures to strengthen the capacity of countries in responding to health emergencies, and to enhance collaboration between countries by better connecting regional and global surge response mec
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hanisms, facilitating information exchange, and improving access to expertise and human response capacity at times of need.
This is the first version of the GHEC framework and is intended to be updated as experience is gained with its implementation and adaptation.
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This multi-hazard Health Emergency Alert and Response Framework provides guidance for coordinating emergency response in countries, under the global Health Emergency Preparedness, Resilience and Response (HEPR) framework. It outlines the public health functions, coordination systems and actions need
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ed for effective local, sub-national and national response to a broad range of health emergencies, including disasters. The audience for this framework is the primary national and sub-national authorities with the designated responsibility for health emergency coordination.
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This tool enables a rapid, systematic review of pharmacy curricula at the national or institutional level to evaluate their robustness in delivering the expected content and competencies. It can also assist institutions in designing strategies to strengthen AMR curricular content, and to facilitate
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structured, periodic dialogue on AMR and infection-related competencies among pharmacy faculty and other relevant stakeholders. A pharmacy curriculum that comprehensively integrates AMR content will help ensure that future pharmacists have the knowledge, skills, and attitudes needed to address AMR effectively in both clinical practice and public health.
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Recognizing this need and the role of NPHIs in ensuring health security across the continent, the Africa CDC has prioritized the strengthening of NPHIs as a critical pillar of both the New Public Health Order and the Africa CDC Strategic Plan 2023-2027. To aid the realization of this goal, the Afric
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a CDC has developed a Plan for the Development of National Public Health Institutes in Africa 2025-2027. The goal is to ensure that NPHIs are not only present in every Member State but are also empowered with the necessary legal frameworks, resources and expertise to effectively lead Africa’s health security efforts.
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Hand hygiene is a simple yet powerful tool in interrupting the transmission of the monkeypox virus (MPXV) and other infectious disease both in healthcare facilities and communities. However millions still lack access to basic hygiene services particularly in vulnerable and resource limited settings.
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Governments must urgently ensure universal access to functioning hand hygiene stations in public and healthcare facilities, promote correct hand hygiene practices, and integrate hand hygiene into national polices and response strategies, to contain mpox. There is a need for multimodal approach- combining political leadership, availability of supplies, evidence based behavioral change strategies and strengthened healthcare practices is critical.
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The purpose of this interim guidance is to provide recommendations for planning and implementing RCCE activities that protect and empower communities during MVD outbreaks. The guidance is designed for national and subnational health responders involved in RCCE for MVD readiness and response. It is a
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lso relevant to other stakeholders, such as partner organizations, ministries (such as those involved in social protection), and academics, who contribute to RCCE activities. The document is meant to be adapted alongside national multi-risk/ multisectoral plans, leveraging existing expertise, coordination mechanisms and partnerships.
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The resurgence of mpox in multiple African countries since 2022 has highlighted urgent gaps in preparedness, detection, and response capacities across the continent. While the mpox outbreak was initially classified as a Public Health Emergency of International Concern (PHEIC) and a Public Health Eme
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rgency of Continental Security (PHECS), the risk of continued transmission in high-risk areas of Africa remains significant, particularly due to persistent zoonotic reservoirs, cross-border spread, and fragile surveillance systems.
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The Marburg Virus Disease (MVD) Response Plan outlines Tanzania’s national strategy for responding to a Marburg virus outbreak declared in the Kagera Region in January 2025. The document describes the current epidemiological situation, assesses the risks posed by the outbreak, and sets strategic o
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bjectives to contain the disease and prevent further transmission. It details response measures across multiple sectors, including surveillance, laboratory testing, case management, infection prevention and control, risk communication, logistics, and community engagement. Furthermore, the plan defines coordination mechanisms, operational procedures, monitoring indicators, and the financial resources required to implement the response. Overall, the plan serves as a comprehensive framework to guide national and international stakeholders in controlling the outbreak and protecting public health.
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Filoviral hemorrhagic fever (FHF) is caused by ebolaviruses and marburgviruses, which both belongto the family Filoviridae. Egyptian fruit bats (Rousettus aegyptiacus) are the most likely natural reservoir for marburg viruses and entry into caves and mines that they stay in has often been associated
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with outbreaks of MVD. On the other hand, the natural reservoir for ebola viruses remains elusive;however, handling of wild animal carcasses has been associated with some outbreaks of EVD. In thelast two decades, there has been an increase in the incidence of FHF outbreaks in Africa, some beingcaused by a newly found virus and some occurring in previously unaffected areas such as Guinea, Liberia and Sierra Leone, in which the most recent EVD outbreak occurred in 2014. Indeed, the predicted geographic distribution of filoviruses and their potential reservoirs in Africa includes manycountries in which FHF has not been reported. To minimize the risk of virus dissemination inpreviously unaffected areas, there is a need for increased investment in health infrastructure in African countries, policies to facilitate collaboration between health authorities from different countries, implementation of outbreak control measures by relevant multi-disciplinary teams and education of the populations at risk.
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Between April 2018 and November 2020, the Democratic Republic of Congo (DRC) experienced its 11th Ebola virus disease (EVD) outbreak. Tanzania’s cross-border interactions with DRC through regular visitors, traders, and refugees are of concern, given the potential for further spread to neighboring
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countries. This study aimed to estimate the risk of introducing EVD to Tanzania from DRC. National data for flights, boats, and car transport schedules from DRC to Tanzania covering the period of May 2018 to June 2019 were analyzed to describe population movement via land, port, and air travel and coupled with available surveillance data to model the risk of EVD entry. The land border crossing was considered the most frequently used means of travel and the most likely pathway of introducing EVD from DRC to Tanzania. High probabilities of introducing EVD from DRC to Tanzania through the assessed pathways were associated with the viability of the pathogen and low detection capacity at the ports of entry. This study provides important information regarding the elements contributing to the risk associated with the introduction of EBV in Tanzania. It also indicates that infected humans arriving via land are the most likely pathway of EBV entry, and therefore, mitigation strategies including land border surveillance should be strengthened.
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This review article examines 42 years of Ebola virus disease (EVD) outbreaks in Sub-Saharan Africa, from 1976 to 2019. The authors analyze the epidemiology, geographical distribution, mortality rates, and response strategies associated with 34 Ebola outbreaks across 11 African countries. The review
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identifies key challenges in controlling Ebola, including weak health systems, limited surveillance and laboratory capacity, sociocultural practices, environmental changes, and community mistrust. It also discusses advances in diagnostics, treatments, and vaccines, and emphasizes the importance of a One Health approach, community engagement, effective communication, and stronger healthcare systems to improve preparedness, prevention, and response to future Ebola outbreaks.
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If you think you might have monkeypox, self-isolate and contact a health worker immediately. If your symptoms become worse, seek immediate medical advice
This is a video from CORE TRAINING about Infection Prevention and Control Training. It deals with subjects of MRSA, C.difficile, Isoliation, Hand Hygiene, PPE and contaminated waste.
