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HIV-1 drug resistance (HIVDR) genotyping is an essential component of the WHO global HIVDR surveillance strategy. Plasma “gold standard” specimen type for HIVDR genotyping, but its use may not be feasible in rural, remote areas in low- and middl
...
e-income countries, since preparing and storing it require personnel and laboratory infrastructure that are often lacking. An alternative specimen type is dried blood spots (DBS), which can be made without special laboratory processing. DBS are more easily transported than plasma because they can be shipped at ambient temperature as non-hazardous materials using regular mail or courier services.
3rd edition
more
The WHO’s Early Warning, Alert and Response System (EWARS) is a tool used in emergencies such as conflicts or natural disasters to quickly detect and respond to disease outbreaks. It helps set up simple and reliable surveillance systems even in pl
...
aces without stable electricity or internet, using kits that include phones, laptops, and solar chargers. EWARS supports national health authorities during crises and can later be integrated into the regular health surveillance system.
more
The document provides a standardized protocol for evaluating the Early Warning Alert and Response Network (EWARN), a surveillance system used during humanitarian emergencies when regular national health
...
surveillance may be disrupted. The purpose of EWARN is to detect outbreaks of communicable diseases early and enable rapid public health response. The guidance explains how the system should be assessed in terms of its structure, implementation, effectiveness, and usefulness. It outlines the key steps of evaluation: preparation, system description, data collection, and post-evaluation reporting. The protocol highlights common challenges observed in previous EWARN implementations, such as delays in establishing the system, limited data quality, weak outbreak response, and lack of clear transition plans back to routine surveillance systems. It emphasizes the need to evaluate both weekly disease reporting and alert verification processes, and to review attributes such as simplicity, data quality, timeliness, sensitivity, and stability. The document also provides templates for interviews, data review forms, and laboratory assessment, as well as guidance on conducting remote evaluations when access is limited. The overall goal of the protocol is to ensure that EWARN functions effectively to detect and respond to outbreaks and that practical recommendations are developed to improve the system’s performance and sustainability in emergency settings.
more
The strategy focuses on mobilizing and coordinating partners, experts and resources to help countries enhance surveillance of the Zika virus and disorders that could be linked to it, improve vector control, effectively communicate risks, guidance an
...
d protection measures, provide medical care to those affected and fast-track research and development of vaccines, diagnostics and therapeutics
more
Data for Global Pandemic and Epidemic Intelligence
Fitzner, J.; – WHO Hub for Pandemic and Epidemic Intelligence
World Health Organization (WHO)
(2025)
C_WHO
The presentation “Data for Global Pandemic and Epidemic Intelligence” outlines how improved data collection, surveillance, analytics, and digital tools can strengthen global preparedness and response to
...
health emergencies. It explains the concept of epidemic intelligence, highlighting the integration of multiple data sources—such as traditional surveillance, genomics, open-source information, and modelling—to support timely and evidence-based decision-making. The presentation also showcases initiatives of the WHO Hub for Pandemic and Epidemic Intelligence, including collaborative data platforms, pathogen genomics networks, analytic communities of practice, and a decision-support pandemic simulator designed to enhance rapid, coordinated responses to future outbreaks.
more
HIV drug resistance strategies focus on prevention through adherence and treatment optimization, surveillance to monitor resistance trends, and innovation in new drugs and diagnostics. Key approaches include implementing national action plans, stren
...
gthening laboratory capacity for monitoring, and providing comprehensive care, especially for vulnerable populations
more
Maladies non transmissibles 2024
World Health Organization WHO; Eastern Mediterranean Region
World Health Organization (WHO)
(2024)
C_WHO
The WHO Eastern Mediterranean Region's Noncommunicable Diseases (NCD) Data and Statistics page offers comprehensive information on NCD surveillance, including mortality rates, morbidity, and risk factor exposures. It emphasizes the importance of mon
...
itoring NCD trends to inform prevention and control strategies, aligning with global targets such as reducing premature NCD deaths by one-third by 2030. The page also highlights the WHO STEPwise approach to NCD risk factor surveillance, providing standardized methods for data collection and analysis.
more
Launch of the WHO Report on antimalarial drug efficacy, resistance and response: 10 years of surveillance (2010–2019). Key findings
WHO Essential Regulatory Laboratories (ERLs), inside the Global Influenza Surveillance and Response System (GISRS), are a crucial element of influenza prevention and control, especially vaccine response.
This Framework offers a coherent approach for eliminating tuberculosis (TB) in low-incidence countries. It is designed to guide national policy-makers and those responsible for technical aspects of the national TB response in accelerating efforts towards elimination. The document will also be inform
...
ative for public health surveillance officers, practitioners and nongovernmental and civil society partners working on natioal TB care and prevention and serving the populations most vulnerable to TB.
more
A survey was conducted in countries in all six WHO regions and focused on the building blocks that are considered prerequisites to combat antimicrobial resistance: a comprehensive national plan, laboratory capacity to undertake surveillance for resi
...
stant microorganisms, access to safe, effective antimicrobial medicines, control of the misuse of these medicines, awareness and understanding among the general public and effective infection prevention and control programmes.
more
Many critical questions remain about the effectiveness of COVID-19 vaccines in real-world settings. These questions can only be answered in post-introduction vaccine effectiveness studies.This guidance document outlines an approach to leverage existing sur
...
veillance systems for Severe Acute Respiratory Infection (SARI) to estimate COVID-19 vaccine effectiveness (VE) in preventing SARI associated with laboratory-confirmed SARS-CoV-2 using existing SARI surveillance systems. The approach uses the test-negative design to evaluate VE; cases are SARI patients who tested positive for SARS-CoV-2, and controls are SARI patients who tested negative for SARS-CoV-2.
more
Rabies has an enormous impact on both agriculture and conservation biology, but its greatest burden is undeniably on public health. As such, routine methods for rapid risk assessment after human exposures to rabies as well as applications for labora
...
tory-based surveillance, production of biologicals and management of this infectious disease are critical. Given its mandate to improve human health and control disease among its Member States, WHO has led the production of this fifth edition of Laboratory techniques in rabies.
more
Laboratory manual for yellow fever
recommended
This WHO laboratory manual provides the most up to date methods and procedures for the laboratory identification of yellow fever virus infection in humans. It provides guidance on the establishment and maintenance of an effective laboratory providing routine
...
surveillance testing for yellow fever, which operates within the WHO coordinated Global Yellow Fever Laboratory Network (GYFLaN) capable of providing confirmation of yellow fever infection reliably and timely. This second edition supersedes the first edition of the 2004 WHO manual for the monitoring of yellow fever virus infection.
more
The WHO handbook “Epidemiological Data Analysis for the Early Warning Alert and Response Network (EWARN) in Humanitarian Emergencies” explains how to collect, analyse, interpret, and share health data during crises such as conflicts or natural d
...
isasters. It is a practical guide for health and surveillance officers to detect disease outbreaks early and guide quick public health responses. The document outlines steps for managing data at different levels (local, regional, national), analysing disease trends by time, place, and person, and using indicators to monitor outbreak risks. It also provides methods for interpreting and communicating results clearly to decision-makers to support effective health interventions in emergencies.
more
The WHO country office for Ghana, began the year 2019 with a 4-day staff retreat at the Busua Beach Resort in the Western Region from 04 to 08 March 2019. The theme for the retreat was ‘Impacting the Health and Lives of the people of Ghana through
...
the Triple Billion Goal”. The staff outlined priorities and strategies to strengthen WHO’s contribution to the national health agenda during the year. Working in collaboration with the Ministry of Health/Ghana Health Service and other allied health institutions and stakeholders, the WHO country office, provided support aimed at achieving its
mission which is attaining the highest level of health by the people in the country though its six operational areas which are (i) Communicable Diseases (ii) Non-Communicable Diseases, (iii) Promoting Health through the Life Course (iv), Health Systems, (v) Preparedness, Surveillance and Response (vi) Corporate services and enabling functions.
more
The Zimbabwe Multi-Sectoral Cholera Elimination Plan (2018–2028) aims to eradicate cholera by improving water, sanitation, and healthcare infrastructure, strengthening disease surveillance, and expanding oral cholera vaccination (OCV). The strateg
...
y focuses on five pillars, including public health response, WASH, infrastructure, community empowerment, and financing. A multi-sectoral approach involving government, international organizations, and local communities targets cholera hotspots to prevent outbreaks and ensure long-term disease control.
more
Guidance for Immunization Programmes in the African Region in the Context of Ebola - Revised 30 March 2015*
World Health Organization
(2015)
Practical guidance on immunization services and the risks they present for both Ebola affected and non-affected countries. The specific purpose of this document is to assist countries to:
- Maintain immunization services and use immunization contacts and
...
surveillance system as opportunities to educate and monitor for Ebola;
- Provide guidance on infection prevention and control during vaccination;
- Prepare where there is a potential risk of Ebola (e.g. border, etc.) and low immunization coverage, to implement activities to increase immunization coverage in these areas.
more
The document provides detailed guidelines for managing cholera outbreaks, focusing on prevention, diagnosis, treatment, and control strategies. It emphasizes the importance of setting up Cholera Treatment Centers (CTCs), ensuring access to clean water, promoting hygiene, and utilizing oral rehydrati
...
on solutions (ORS) and antibiotics for treatment. The guide also addresses outbreak surveillance, community education, and resource allocation to effectively mitigate cholera's spread and impact.
more
These interim case definitions have been developed for the purpose of providing global standardization for classification and reporting of Zika virus cases. WHO guidance for the surveillance of Zika virus disease is currently being developed.
WHO w
...
ill periodically review these interim case definitions and update them as new information becomes available
more
