The conditionality of this recommendation is largely driven by the current higher unit cost of pyrethroid-PBO ITNs compared
to pyrethroid-only LLINs and therefore the uncertainty of their cost-effectiveness. Furthermore, as PBO is less wash-resistant
than pyrethroids, its bioavailability declines ...faster over the three-year estimated life of an ITN; therefore, the added impact of
pyrethroid-PBO ITNs over that of pyrethroid-only LLINs may decline over time. The evidence comes from two sites in
eastern Africa with pyrethroid resistance and not from other geographies where transmission levels and vector characteristics
may vary. PBO acts by inhibiting certain metabolic enzymes, primarily oxidases, and so are likely to provide greater protection
than pyrethroid-only LLINs where mosquitoes display mono-oxygenase-based insecticide resistance mechanisms.
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PLoS Negl Trop Dis 16(11): e0010885. https://doi.org/10.1371/journal.pntd.0010885
HAT diagnosis in non-endemic countries is rare and can be challenging, but alertness and
surveillance must be maintained to contribute to WHO’s elimination goals. Early detection is
particularly important as it co...nsiderably improves the prognosis.
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Original publication developed by CBM. CBM is an international Christian disability & development organisation committed to improving the quality of life of persons with disabilities in the poorest parts of the world. www.cbm.org
Timely detection of novel coronavirus (2019-nCoV) infection cases is crucial to interrupt the spread of this virus. We assessed the required expertise and capacity for molecular detection of 2019-nCoV in specialised laboratories in 30 European Union/European Economic Area (EU/EEA) countries. Thirty-...eight laboratories in 24 EU/EEA countries had diagnostic tests available by 29 January 2020. A coverage of all EU/EEA countries was expected by mid-February. Availability of primers/probes, positive controls and personnel were main implementation barriers.
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La flambée de maladie à virus Ebola (MVE) se poursuit avec une intensité modérée. Katwa et Butembo demeurent les principales zones sanitaires inquiétantes, tandis que de petites grappes continuent d’apparaître dans diverses zones géographiquement dispersées. Au cours des 21 derniers jours... (6 - 26 février 2019), 77 nouveaux cas ont été notifiés dans 33 secteurs de neuf zones sanitaires (Figure 1) : Katwa (45), Butembo (19), Vuhovi (4), Kyondo (3), Kalunguta (2), Oicha (1), Beni (1), Mandima (1) et Rwampara (1).
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The document provides a comprehensive overview of malaria, covering its global impact, transmission, symptoms, diagnosis, treatment, prevention strategies, and the role of public health interventions—especially in high-risk regions like sub-Saharan Africa—to reduce its incidence and mortality.
This document aims to provide guidance to EU/EEA public health authorities, public health professionals and healthcare practitioners for the management of persons having had contact with cases of Ebola virus disease (EVD) after visiting or working in an area that is affected by EVD; also covered is ...occupational exposure to the disease
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Adapted from CURRENT Medical Diagnosis & Treatment 2010