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Efficacy and effectiveness of an rVSV-vectored vaccine expressing Ebola surface glycoprotein: interim results from the Guinea ring vaccination cluster-randomised trial

Ana Maria Henao-Restrepo, Ira M Longini, Matthias Egger, et al. (2015)
the Lancet : Published Online July 31, 2015 http://dx.doi.org/10.1016/S0140-6736(15)61117-5
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Efficacy and effectiveness of an rVSV-vectored vaccine in preventing Ebola virus disease: final results from the Guinea ring vaccination, open-label, cluster-randomised trial (Ebola Ça Suffit!)

Henao-Restrepo, A.M.; et al. (2016)
The Lancet. Published Online December 22, 2016 http://dx.doi.org/10.1016/S0140-6736(16)32621-6. Open Access
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Emergency Use Designation of COVID-19 candidate vaccines: Ethical considerations for current and future COVID-19 placebo-controlled vaccine trials and trial unblinding

World Health Organization WHO (2020) C_WHO
The conduct of COVID-19 vaccine trials in the context of a candidate vaccine being issued with Emergency Use Designation raises challenging ethical questions, including in relation to the use of pla ... more
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Safety and efficacy of malaria vaccine candidate R21/Matrix-M in African children: a multicentre, double- blind, randomised, phase 3 trial

Datoo, M.S.; A. Dicko, H.Tinto, et al. (2024) CC
Lancet 2024; 403: 533–44 R21/Matrix-M was well tolerated and offered high efficacy against clinical malaria in African children. This low-cost, high-efficacy vaccine is already licensed by several African countries, and recently received a WHO p ... more
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Effect of a single inactivated poliovirus vaccine dose on intestinal immunity against poliovirus in children previously given oral vaccine: an open-label, randomised controlled trial

Jacob John, et al. The Lancet (2014)
The Lancet, Early Online Publication, 11 July 2014 doi:10.1016/S0140-6736(14)60934-X *Free registration is required to view this article
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Safety and efficacy of an rAd26 and rAd5 vector-based heterologous prime-boost COVID-19 vaccine: an interim analysis of a randomised controlled phase 3 trial in Russia

Logunov, D.Y, et al. (2021) C1
Published:February 02, 2021DOI:https://doi.org/10.1016/S0140-6736(21)00234-8
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WHO Sciene in 5 #13 - COVID-19 - Vaccine trials

World Health Organization WHO (2021) C_WHO
Learn what scientists look for in the different phases of a clinical trial for a vaccine. What does it mean when a vaccine ... more
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COVID-19 vaccine tracker and landscape
recommended

World Health Organization WHO (2022) C_WHO
The COVID-19 vaccine tracker and landscape compiles detailed information of each COVID-19 vaccine candidate in development by closely monitoring their progress through the pipeline. The COVID-19 ... more
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How does the Pfizer COVID vaccine work?

BioDigital (2020) CC
Exciting news this week with @Pfizer reporting their mRNA vaccine is 90% effective, based on their Phase III clinical trial data. Dr. Tom looks inside the virus to break down how mRNA vaccines work, ... more
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How does Moderna's Coronavirus vaccine work?

The Telegraph (2020) CC
Early data from US biotech Moderna has revealed that its Covid-19 vaccine candidate is 94.5 per cent effective, raising hopes that a range of immunisations will be available to help end the pandemic. The interim analysis of the ... more
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Africa CDC Consortium for COVID-19 Vaccine Clinical Trials (CONCVACT)

African Union; Africa CDC Centres for Disease Control and Prevention (2020) C1
August 2020, The Africa Joint Continental Strategy for COVID-19 is underpinned by the need to limit transmission, prevent deaths and reduce associated harms. Participation by African nations in clinical trials is an essential step to ensure that sufficient data is generated on the safety and efficac ... more
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Answers to common questions about the Ebola prevention marklate study.

Ministry of Health & Sanitation, Sierra Leone (2015)
Sierra Leone Trial to Introduce a Vaccine against Ebola (STRIVE)
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How are vaccines developed?

World Health Organization WHO (2021) C_WHO
This article is part two in a series of explainers on vaccine development and distribution. Part one focused on how vaccines work to protect our bodies from disease-carrying germs. This article focuses on the ingredients in a ... more
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The different types of COVID-19 vaccines

World Health Organization WHO (2020) C_WHO
This article is part four in a series of explainers on vaccine development and distribution. Part one focused on how vaccines work to protect our bodies from disease-carrying germs. Part two focused on the ingredients in a ... more
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Manufacturing, safety and quality control of vaccines

World Health Organization WHO (2020) C_WHO
This document is part three in a series of explainers on vaccine development and distribution. Part one focused on how vaccines work to protect our bodies from disease-carrying germs. Part two focused on the ingredients in a ... more
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COVID-19 Vaccine Resource Center
recommended

New England Journal of Medicine (2021) C1
A collection of resources on Covid-19 vaccines, including frequently asked questions, continuing medical education, published research, and commentary.
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Statement on the Efficacy of the AstraZeneca COVID-19 Vaccine (ChAdOx1 nCoV-19) against the SARS-CoV-2 Variants
recommended

African Union; Africa CDC Centres for Disease Control and Prevention (2021) C1
On the 9 February 2021, Africa CDC convened a special session of the Africa Task Force for COVID-19 to review existing data and evidence and recommend
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Covaxin

Bharat Biotech (2021) CC
COVAXINTM, India's indigenous COVID-19 vaccine by Bharat Biotech is developed in collaboration with the Indian Council of Medical Research (ICMR) - National Institute of Virology (NIV). The indigenous, inactivated ... more
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Frequently Asked Questions (FAQs) about COVID-19 Candidate Vaccines and Access Mechanisms. Version 3, 6 January 2021

Pan American Health Organisation PAHO (2021) C_WHO
Will COVID-19 vaccines be safe? Will all the COVID-19 candidate vaccines be successful? What are the different phases a vaccine must go through to be approved? This document provides responses to the most frequently asked questions about candidate v ... more
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Ebola research and development landscape of clinical candidates and trials

World Health Organization (WHO) (2015) C_WHO
The report presents current information (updated to September 2015) on candidate vaccines, therapies and medical devices for Ebola and gives an overview of completed and on-going trials.