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Helminths Filarisasis

RWJF Microbiology, Immunology & Infectious Diseases (2016) C2

This video is part of a comprehensive medical school microbiology, immunology & infectious diseases course. Your comments on videos will be key as we iterate content.

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Assessing the feasibility of interrupting the transmission of soil-transmitted helminths through mass drug administration: The DeWorm3 cluster randomized trial protocol

Ásbjörnsdóttir K.H., Ajjampur S.S.R., Anderson R.M. et al (2018) C2

Soil-transmitted helminths (STH) affect 1.45 billion people worldwide, and high intensity infections are associated with anemia, undernutrition and impaired cognition, particularly among children. Mathematical models suggest it may be possible to in ... more

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CDC - Soil-Transmitted Helminths

Centers for Disease Control and Prevention CDC (2023) C2

Website last accessed on 24.03.2023 Education and information about Soil-Transmitted Helminths including Human Hookworm, Roundworm and Whipworm.

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Deadly Worms!!! – A look at Soil Transmitted Helminths

Let's learn abut bugs (2023) C2

Website last accessed on 31.03.2023 Youtube Video (Explainity)

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Diagnostic Techniques for Soil-Transmitted Helminths – Recent Advances

Khurana S., Singh S. Dovepress (2021) C2

Diagnostic performance, cost-effectiveness, ease of performance, rapidity and in-field applicability of tests for Soil-transmitted helminth infections.

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Prevalence of Schistosoma mansoni, soil-transmitted helminths and intestinal protozoa in orphans and street children in Mwanza city, Northern Tanzania

Franz, A.; A. Fuss, H.D. Mazigo, (2023) CC

Infection 2023 Oct;51(5):1399-1406. doi: 10.1007/s15010-023-01999-9. Epub 2023 Feb 20. The results indicate a significantly higher rate of infections with S. mansoni in street children compared with orphans. This might be explained by the lack of access to adequate sanitation for street children ... more

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Diagnostic target product profile for monitoring and evaluation of soil-transmitted helminth control programmes

World Health Organization WHO (2021) C_WHO

Soil-transmitted helminths are a group of intestinal worms that include Ascaris lumbricoides (giant roundworm), Trichuris trichiura (whipworm), and Ancylostoma spp. (A. duodenale, A. ceylanicum) and Necator americanus (hookworms). Despite the clear ... more

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Integrated community-based intervention for urinary schistosomiasis and soil-transmitted helminthiasis in children from Caxito, Angola

Lemosa, M.; Fançonya, C.; Moura, S. et al The royal society of tropical medicine and hygiene (2020) C2

Schistosomiasis and soil-transmitted helminths (STH) infections are major public health problems. We aimed to study the 6-mo impact of mass drug administration with praziquantel and albendazole on urinary schistosomiasis and STH.We examined children ... more

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Soil-Transmitted Helminthiasis in Children from a Rural Community Taking Part in a Periodic Deworming Program in the Peruvian Amazon

Errea, R.; Vasquez-Rios, G.; Calderon, M.; The American Jornal of Tropical Medicine and Hygiene (2019) CC

Infections by the soil-transmitted helminths (STH), including Ascaris lumbricoides, Trichuris trichiura, Ancylostoma duodenale/Necator americanus (hookworms), and Strongyloides stercoralis, disproportionately affect children around the world. Becaus ... more

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Parasitic Diseases Lectures #28: Lymphatic Filariasis

Parasites Without Borders (2018) CC

Dickson and Daniel discuss lymphatic filariasis caused by the helminths Wuchereria bancrofti and Brugia malayai.

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Current epidemiological evidence for predisposition to high or low intensity human helminth infection: a systematic review

Wright J.E., Werkman M., Dunn J.C. et al Parasites and Vectors (2018) C2

Background: The human helminth infections include ascariasis, trichuriasis, hookworm infections, schistosomiasis, lymphatic filariasis (LF) and onchocerciasis. It is estimated that almost 2 billion people worldwide are infected with helminths. Whils ... t the WHO treatment guidelines for helminth infections are mostly aimed at controlling morbidity, there has been a recent shift with some countries moving towards goals of disease elimination through mass drug administration, especially for LF and onchocerciasis. However, as prevalence is driven lower, treating entire populations may no longer be the most efficient or cost-effective strategy. Instead, it may be beneficial to identify individuals or demographic groups who are persistently infected, often termed as being “predisposed” to infection, and target treatment at them. Methods: The authors searched Embase, MEDLINE, Global Health, and Web of Science for all English language, humanbased papers investigating predisposition to helminth infections published up to October 31st, 2017. The varying definitions used to describe predisposition, and the statistical tests used to determine its presence, are summarised. Evidence for predisposition is presented, stratified by helminth species, and risk factors for predisposition to infection are identified and discussed. Results: In total, 43 papers were identified, summarising results from 34 different studies in 23 countries. Consistent evidence of predisposition to infection with certain species of human helminth was identified. Children were regularly found to experience greater predisposition to Ascaris lumbricoides, Schistosoma mansoni and S. haematobium than adults. Females were found to be more predisposed to A. lumbricoides infection than were males. Household clustering of infection was identified for A. lumbricoides, T. trichiura and S. japonicum. Ascaris lumbricoides and T. trichiura also showed evidence of familial predisposition. Whilst strong evidence for predisposition to hookworm infection was identified, findings with regards to which groups were affected were considerably more varied than for other helminth species. Conclusion: This review has found consistent evidence of predisposition to heavy (and light) infection for certain human helminth species. However, further research is needed to identify reasons for the reported differences between demographic groups. Molecular epidemiological methods associated with whole genome sequencing to determine ‘who infects whom’ may shed more light on the factors generating predisposition. more

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Diagnostic methods for the control of strongyloidiasis, Virtual meeting, 29 September 2020

World Health Organization WHO (2021) C_WHO

23 March 2021 The meeting addressed the last key area, that is, determining the best method or combination of diagnostic methods for a control programme for S. stercoralis infections in humans. Dr Montresor’s presentation highlighted that while there is currently no “gold standard” for the ... more

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HELP - Helminthiasis factsheet

HELP - Helminth Elimination Platform (2023) C2

Accessed on 22.04.2023 To target helminth elimination, a new consortium of research institutes, universities, not-for-profit organizations, and pharmaceutical companies have joined forces and expertise to establish a research and development pipeline for the development of anthelminthics targeti ... more

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Preventive chemotherapy to control soil-transmitted helminth infections in at-risk population groups
recommended

A. Montresor World Health Organisation (WHO) (2017) C_WHO

Treating children infected with intestinal worms is one of the simplest and most cost–effective ways to improve their health. The recommendations are intended for a wide audience, including policy-makers and their expert advisers as well as technical and programme staff at government institution ... more

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Bambo tem equistossomose: O que as crianças devem saber sobre a esquistossomose

Organização Mundial da Saúde OMS (2014) C_WHO

Comic Book

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Bambo tem equistossomose: O que as crianças devem saber sobre a esquistossomose. African Portuguese Edition

Organização Mundial da Saúde OMS (2014) C_WHO

Comic Book. African Portuguese Edition

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Burden of disease from inadequate water, sanitation and hygiene for selected adverse health outcomes: An updated analysis with a focus on low- and middle-income countries

Prüss-Ustün A., Wolf J., Bartram J., et al. (2019) CC

Int J Hyg Environ Health. 2019 Jun; 222(5): 765–777. doi: 10.1016/j.ijheh.2019.05.004; To develop updated estimates in response to new exposure and exposure-response data of the burden of diarrhoea, respiratory infections, malnutrition, schistosomiasis, malaria, soil-transmitted helminth infec ... more