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March 2025. Access to appropriate, quality-assured diagnostics remains a challenge. There is limited information on key characteristics of available test kits, including their performance, reliability, and ability to detect relevant Mpox clades. Additionally, the lack of multiplex diagnostic tools c ... more
The monkeypox virus (MPXV) clade I epidemic that has been affecting the Democratic Republic of the Congo (DRC) since November 2023 has recently spread to several other African countries including Burundi, Rwanda, Uganda and Kenya. The size of these outbreaks could be larger than reported due to un ... more
Mpox can spread in humans through close contact, usually skin-to-skin contact, including sexual contact, with an infected person or animal, as well as with materials contaminated with the virus such as clothing, beddings and towels, and respiratory droplets in prolonged face to face contact. People ... more
WHO has updated the mpox Case reporting form (CRF) and data collection tool, mainly by reducing the number of variables. A detailed list of changes is presented in the file. The content of the Case investigation form (CIF) has not been changed.
Resource Platform
L’orthopoxvirus simien ou virus de la variole du singe (MPXV), est un virus à ADN double brin qui appartient au genre Orthopoxvirus de la famille des Poxviridés. Les poxvirus causent des maladies chez l’espèce humaine et beaucoup d’autres animaux ; l’infection se manifeste généralement ... more

Monkeypox

Mauder, S. MEDBOX (2022) CC
MEDBOX Issue Brief no.22, updated August 9, 2022
This document summarises the available data on MVA-BN (Imvanex) including from previous experience of use of this vaccine in contacts of monkeypox cases in the UK and details the current advice of an expert working group (see Appendix 1 for details) on the use of this vaccine for pre- and post-ex ... more
Presentation
The goal of the global outbreak response for monkeypox is to stop human-to-human transmission of monkeypox, with a priority focus on communities at high risk of exposure which may differ according to context, and to effectively use strong public health measures to prevent onward spread of the diseas ... more
Any individual that meets the suspected case definition of monkeypox should be offered testing in appropriately equipped laboratories by staff trained in the relevant technical and safety procedures. Confirmation of monkeypox virus infection is based on nucleic acid amplification testing (NAAT), usi ... more
The Lancet Group publishes the latest monkeypox-related content across epidemiology, treatments, and much more. Here you can explore monkeypox content published across all Lancet journals and content types. All of our monkeypox content is free to access.
21 juillet 2022
15 May 2022
This publication provides information for identifying, classifying, marking, labelling, packaging, documenting and refrigerating infectious substances for transportation and ensuring their safe delivery. The document provides practical guidance to facilitate compliance with applicable international ... more
In a retrospective review of hospital records of 40 human monkeypox cases from Nigeria, the majority developed fever and self-limiting vesiculopustular skin eruptions. Five deaths were reported. Compared to human immunodeficiency virus (HIV)–negative cases, HIV type 1–coinfected cases had more ... more
This document provides information and recommendations for action, based on the current available knowledge around monkeypox. It is a first draft which will be updated in light of evolving evidence and additional information as they become available.