In the early morning of 6 February 2023, a magnitude 7.8 earthquake occurred in southern Türkiye near the northern border of Syria. The earthquake was followed 11 minutes later by a magnitude 6.7 aftershock. Many aftershocks are still being felt across the region. Whilst the impact is still being assessed, initial reports evidence significant damage in the areas of southern Türkiye and northern Syria. In response, the Syria Ministry of Health (MoH) activated its emergency operations centre (EOC) on 6 Feb 2023 under the chairmanship of the Deputy Minister. In all affected governorates, public and private health facilities and medical convoys have been repurposed to support the response and are being managed by the National Ministry of Health (MoH) and Directorate of Health (DoH) at governorate level. Support has been directed to affected areas, with medical convoys including 28 ambulances and 7 mobile clinics, deployed from the health directorates of Damascus, Rural Damascus, Quneitra, Homs, Tartous, Aleppo and Latakia