Rabies is a global public health problem with important socioeconomic impacts. Human rabies is preventable; almost all cases are transmitted through the bite of a rabid dog. Elimination of human rabies is possible. Technical support and tools are available. This report covers:<br> - Why investment is needed: key rationale.<br> - Investment purpose: global elimination of rabies.<br> - Investment in action: four case examples in Philippines, Kwa-Zulu Natal, South Africa, United Republic of Tanzania, Bangladesh.<br> - Summary results of case examples: Programme similarities and differences, and Health impact success stories from case examples.