Our Recommendations
- Outcomes of lenacapavir administration during pregnancy (2025)
- Mathematical modelling of lenacapavir: landscaping review on impact and cost–effectiveness (2025)
- Should HIV testing services with rapid diagnostic tests and/or self-tests be used for initiation or continuation of injectable long-acting PrEP? (2025)
- Systematic review of values and preferences for lenacapavir as pre-exposure prophylaxis and other forms of long-acting injectable PrEP (2025)
- Safety and efficacy of long-acting injectable lenacapavir as pre-exposure prophylaxis to reduce the risk of HIV acquisition: a systematic review (2025)
New Publications
- Outcomes of lenacapavir administration during pregnancy (2025)
- Lenacapavir-associated drug resistance: implications for scaling up long-acting PrEP (2025)
- Mathematical modelling of lenacapavir: landscaping review on impact and cost–effectiveness (2025)
- Should HIV testing services with rapid diagnostic tests and/or self-tests be used for initiation or continuation of injectable long-acting PrEP? (2025)
- Systematic review of values and preferences for lenacapavir as pre-exposure prophylaxis and other forms of long-acting injectable PrEP (2025)
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Module 5
Monitoring and Evaluation
October 2018
Module 5: Monitoring and evaluation. This module is for people responsible for monitoring PrEP programmes at the national and site levels. It provides information on how to monitor PrEP for safety and effectiveness, suggesting core and additiona...
Module 2
Community Educators and Advocates
July 2017
Module 2: Community educators and advocates. Community educators and advocates are needed to increase awareness about PrEP in their communities. This module provides information on PrEP that should be considered in community-led activities ...
Development of IEC materials for the NDoH launch of oral PrEP at selected sex worker sites in South Africa
Module 9
Strategic planning
July 2017
Module 9: Strategic planning. As WHO recommends offering PrEP to people at substantial HIV risk, this module offers public health guidance for policy-makers on how to prioritize services, in order to reach those who could benefit most from PrEP, and in wh...
Training materials for healthcare workers
Module 4
Leaders
July 2017
Module 4: Leaders. This module aims to inform and update leaders and decision-makers about PrEP. It provides information on the benefits and limitations of PrEP so that they can consider how PrEP could be effectively implemented in their own settings. It also contai...
Module 1
Clinical
July 2017
Module 1: Clinical. This module is for clinicians, including physicians, nurses and clinical officers. It gives an overview of how to provide PrEP safely and effectively, including: screening for substantial risk of HIV; performing appropriate testing before initi...
Module 6
Pharmacists
July 2017
Module 6: Pharmacists. This module is for pharmacists and people working in pharmacies. It provides information on the medicines used in PrEP, including on storage conditions. It gives suggestions for how pharmacists and pharmacy staff can monitor PrEP adherence...
Module 10
Testing providers
July 2017
Module 10: Testing providers. This module is for people who provide testing services at PrEP sites and laboratories. It offers guidance in selecting testing services, including screening of individuals before PrEP is initiated and monitoring while they ar...
Module 3
Counsellors
July 2017
Module 3: Counsellors. This module is for staff who counsel people as they consider PrEP or start taking PrEP and support them in coping with side-effects and adherence strategies. Those who counsel PrEP users may be lay, peer or professional counsellors and hea...
Module 8
Site Planning
July 2017
Module 8: Site planning. This module is for people involved in organizing PrEP services at specific sites. It outlines the steps to be taken in planning a PrEP service and gives suggestions for personnel, infrastructure and commodities that could be considered...
Module 1q
PrEP users
July 2017
Module 11: PrEP users. This module provides information for people who are interested in taking PrEP to reduce their risk of acquiring HIV and people who are already taking PrEP – to support them in their choice and use of PrEP. This module gives ideas for cou...
• PrEP is highly effective in preventing the sexual transmission of HIV.
• For PrEP to work well, it’s important to take the pills regularly.
• While PrEP can prevent HIV, it does not protect against other sexually transmitted infections.
Supplement Article
WHO Guidelines for HIV PEP • CID 2015:60 (Suppl 3), S161 - S164
Pre-exposure prophylaxis (PrEP)
Policy Brief
November 2015
This briefing paper provides an overview of pre-exposure prophylaxis (PrEP) for people planning, commissioning or providing HIV prevention activities in the UK. It does this by reviewing thirty key questions about PrEP and how it might be implemented in the UK.
Supplement Article
Antiretrovirals to Prevent HIV Infection • CID 2015:60 (Suppl 3) • S159 - S160
Technical report
February 2015
