A practical tool to help health workers in the clinical and operational management of multidrug-resistant tuberculosis with special focus on the introduction, implementation and management of the nine-month treatment regimen.
Цей документ описує кроки, необхідні для визначення скоригованого інтервалу QT (QTc) в
ході моніторингу ЕКГ пацієнтів, які отримують препарати для лікування ХР ТБ, що... викликають пролонгацію інтервалу QT. Він також надає рекомендації щодо ведення випадків пролонгації QTc.
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Este documento presenta modelos de algoritmos que permiten investigar por métodos bacteriológicos a los pacientes para el diagnóstico de tuberculosis (TB), TB asociada al Virus de Inmunodeficiencia Humana (TB-HIV) y TB drogorresistente (TBDR).
Healthy me, healthy us: a guide for community members about good health and staying healthy with chronic illness
The new, all oral, 20-month MDR-TB regimens range from US $1,600* (using bedaquiline and linezolid for 6 months and levofloxacin as the fluoroquinolone) to US $2,100* (using linezolid for 12 months and moxifloxacin as the fluoroquinolone.
Assurer des prestations optimales dans la chaîne de soins destinés aux patients tuberculeux
Deuxième édition - Juin 2018
The new WHO recommendations for the treatment of isoniazid-resistant, rifampicin-susceptible TB are based upon a review of evidence from patients treated with such regimens by a Guideline Development Group in conformity with WHO requirements for evidence-based policies.
2nd edition.
T The Compendium has been developed as a clear and concise instrument to facilitate the understanding and planning of delivery of high-quality care for everybody affected by TB. It incorporates all recent policy guidance from WHO; follows the care pathway of persons with signs or sympt...oms of TB in seeking diagnosis, treatment and care; and includes key algorithms and cross-cutting elements that are essential to a patient-centered approach in the cascade of TB care.
The Compendium is structured into 33 WHO standards and consolidates all current WHO TB policy recommendations into a single resource, with electronic links to the individual, comprehensive WHO policy guidelines
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A large meta-analysis of observational studies that provided the basis for the recent makeover of global recommendations for multidrug-resistant tuberculosis (MDR-TB) treatment shows that newer and repurposed drugs produced better outcomes and fewer deaths than older treatments.
The meta-analysis... of 50 studies involving 12,000 patients from 25 countries, published yesterday in The Lancet, found that bedaquiline, linezolid, levofloxacin, and moxifloxacin were associated with greater treatment success and reduced mortality compared with the previously recommended first-line treatments, while clofazimine and carbapenem antibiotics were associated with significantly improved treatment outcomes (but not reduced mortality)
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The first important change is a new priority ranking of the available medicines for MDR-TB treatment, based on a careful balance between expected benefits and harms. Treatment success for MDR-TB is currently low in many countries. This could be increased by improving access to the highest-ranked med...icines for all patients with MDR-TB.
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Презентация о туберкулезе и диабете
PLoS ONE 12(7): e0180996. https://doi.org/10.1371/journal.pone.0180996
Consensus -based guidelines for diagnosis, prevention and treatment of tuberculosis in children and adolescents
Key populations brief
Accessed November 2017
Guide pour les pays à faibles revenus.
В данном документе описываются шаги, необходимые для точного измерения интервала QT (QTc) при мониторинге электрокардиографии (ЭКГ) пациентов, получающих краткосроч...ый режим лечения лекарственно-устойчивого туберкулеза (ЛУ-ТБ) или режим, включающий в схему новые препараты. Кроме того, в данном руководстве представлены требования, которые должны быть учтены при приобретении аппарата ЭКГ для мониторинга безопасности лечения пациентов. В силу того, что каждая модель аппарата имеет особые характеристики расчета QTcF (указанные в описании модели), соответственно, это должно быть учтено при выборе и закупе той или иной модели аппарата.
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Int. J. Mol. Sci. 2017, 18, 341, 1 - 10
Guidelines for treatment of drug-susceptible tuberculosis and patient care
Uptsate 2017