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1
Guidance for Orphans and Vulnerable Children Programs
This document aims to provide Ministry of Health guidance on the implementation of PEP and PrEP to prevent HIV transmission and improve overall health outcomes. This comprehensive approach reflects the commitment of all involved in combating HIV and enhancing public health.
This technical brief describes promising models that demonstrate how FBOs could contribute to expanded access to improved HIV and other services for men. These models incorporate a range of WHO-recommended interventions and highlights operational considerations and key success factors. By capitalizi ... more
medRxiv preprint;https://doi.org/10.64898/2026.02.18.26346597. This model application demonstrates that the sudden cessation of USAID and CDC commitments in the largest HIV epidemic in the world leads to increased incidence and mortality and threatens decades of progress in KZN, South Africa. Rest ... more
The Guide on HIV Services for Adolescents Living with HIV (ALHIV) describes organization of adolescent-friendly services to guide heath management teams and health care workers (HCWs) on their roles. It also outlines important aspects to consider when offering comprehensive care to adolescents an ... more
Full Guidelines
Dosing Recommendations for Prevention and Treatment
This report describes efforts in nine countries, supported by the 2gether 4 SRHR programme and other partners, highlighting the results achieved and learning on improving the health and wellbeing of adolescent and young mothers and their families. Key insights include the importance of responsive se ... more
These guidelines provide new and updated recommendations on the use of point-of-care testing in children under 18 months of age and point-of-care tests to monitor treatment in people living with HIV; the treatment monitoring algorithm; and timing of antiretroviral therapy (ART) among people living w ... more

Providing differentiated delivery to children and adolescents

A. Grimsrud; D.Walker; W. Ameyan; S. Brusamento Unicef; World Health Organization; Pata Pata Pata; IAS (2019) C_WHO
Differentiated service delivery is a client-centered approach, simplifying and adapting services to better meet the needs of people living with HIV and reducing unnecessary burdens on the health care system. Differentiated ART delivery for clinically stable children and adolescents is supported by g ... more
The advent of point-of-care (POC) EID technologies is a breakthrough that creates the opportunity to increase coverage of EID testing. It will allow same-day test results and enable the initiation of earlier treatment, as well as address some of the key limitations of conventional EID networks – i ... more
Strategic information and analytics report No 1, published 17 April 2025. 75 out of 106 surveyed countries reported disruptions in at least one essential health service area.
The family-centered approach to reaching every child living with HIV. This report examines the structural barriers impeding equitable access to HIV testing, treatment initiation and long-term adherence – essential elements for sustaining health and well-being for children, adolescents and young wo ... more
Modelling shows that it will be essential to complement lenacapavir with additional prevention options, testing and treatment. See “Meeting reports” at https://www.unaids.org/en/resources/publications/all for a description of models and tools to estimate potential impact and quantifications requ ... more
Southern African HIV Clinicians Society (SAHCS) Clinical Update, May 2022

Approaches of the Lea Toto and APHIAplus nuru ya bonde programs in Kenya

F. Stuer; K. Greenaway USAID; PEPFAR; 4 Children; Catholic Relief Services (2017) C2
Case Study on Improving HIV Testing and Services for Children Orphaned or made Vulnerable by HIV (OVC)
This WHO guidelines highlight innovative, community-led, and peer-driven approaches to reduce HIV risks among key populations—sex workers, trans people, MSM, people who inject drugs, and prisoners. Effective practices integrate services, utilize trained peers for testing (HTS), and provide stigma- ... more
The adopted pillars for the AEVT Plan are a) early testing among children exposed to HIV, syphilis and HBV; b) closing the treatment gap among PBFW and children exposed to HIV, syphilis and HBV; c) prevention of new HIV, syphilis and HBV infections among PBFW; and d) breaking down barriers to access ... more
A Guide for Community Case Workers in OVC Programs. This guide is meant to help you, a community case worker or facility case manager working on an orphans and vulnerable children (OVC) program, to understand your role in supporting multi-month dispensing (MMD) of anti-retroviral (ARV) medicines f ... more