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Malaria and HIV, two of the world’s most deadly diseases, are widespread, but their distribution overlaps greatly in sub-Saharan Africa. Consequently, malaria and HIV coinfection (MHC) is common in the region. In this paper, pertinent publications on the prevalence, impact, and treatment strategie
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s of MHC obtained by searching major electronic databases (PubMed, PubMed Central, Google Scholar, ScienceDirect, and Scopus) were reviewed, and it was found that the prevalence of MHC in SSA was 0.7%–47.5% overall. Prevalence was 0.7%–47.5% in nonpregnant adults, 1.2%–27.8% in children, and 0.94%–37% in pregnant women. MHC was associated with an increased frequency of clinical parasitemia and severe malaria, increased parasite and viral load, and impaired immunity to malaria in nonpregnant adults, children, and pregnant women, increased in placental malaria and related outcomes in pregnant women, and impaired antimalarial drug efficacy in nonpregnant adults and pregnant women. Although a few cases of adverse events have been reported in coinfected patients receiving antimalarial and antiretroviral drugs concurrently, available data are very limited and have not prompted major revision in treatment guidelines for both diseases. Artemisinin-based combination therapy and cotrimoxazole are currently the recommended drugs for treatment and prevention of malaria in HIV-infected children and adults. However, concurrent administration of cotrimoxazole and sulfadoxine–pyrimethamine in HIV-infected pregnant women is not recommended, because of high risk of sulfonamide toxicity. Further research is needed to enhance our understanding of the impact of malaria on HIV, drug–drug interactions in patients receiving antimalarials and antiretroviral drugs concomitantly, and the development of newer, safer, and more cost-effective drugs and vaccines to prevent malaria in HIV-infected pregnant women.
more
This website provides comprehensive guidance on vaccinations, malaria prevention and general health measures for travellers to tropical and developing regions. It emphasises two main vaccination criteria: the administrative requirements of the destination country and the actual health risks to the t
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raveller. Malaria prevention measures include chemoprophylaxis (e.g. atovaquone-proguanil, doxycycline or mefloquine) and vector control methods such as insecticide-treated nets, insect repellents and environmental protection measures. Additional travel health risks covered include bites from other arthropods, envenomations, dog and mammal bites, food and water hygiene, traveller's diarrhoea, and considerations for pregnant women, infants, the elderly, and people with chronic conditions. It strongly recommends carrying a travel medical kit and having a pre-travel consultation. Overall, the document aims to minimise illness and ensure safe travel.
Accessed on 27/08/2025.
more
Malaria remains a significant public health concern in the SADC region, accounting for 20% of childhood deaths, as well as prompting numerous outpatient visits and hospitalisations. Around three-quarters of the population, including 35 million children under the age of five and 8.5 million
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pregnant women, are at risk. Transmission patterns vary from high and stable in the north to malaria-free in the south, with low, unstable and seasonal zones in between. Although interventions such as indoor residual spraying (IRS), insecticide-treated nets (ITNs/LLINs), intermittent preventive treatment in pregnancy (IPTp), rapid diagnostic tests (RDTs), and artemisinin-based combination therapies (ACTs) have reduced the malaria burden, challenges persist in terms of funding, human resources, surveillance, and cross-border coordination. Achieving malaria elimination in the SADC region requires harmonised regional standards, strengthened surveillance, and improved access to quality treatment and policy prioritisation.
Accessed on 27/08/2025.
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FANTA provided technical support to Haiti’s Ministry of Public Health and Population for the development of national guidelines and an accompanying flipchart, which provide practical solutions to nutrition problems for people living with HIV, as well as guidance on nutritionally managing the sympt
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oms of HIV, the side effects of antiretroviral drugs, and opportunistic infections. The guidelines provide recommendations for well-balanced diets for people living with HIV, along with instructions for quality nutrition counseling of adolescents and adults living with HIV, HIV-positive pregnant and lactating women, and caregivers of children exposed to HIV. The guidelines also address food insecurity in HIV-affected households.
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Operational Updates
Emergency Relief & Nutrition Rakhine: A significant increase in internal displacements due to continued armed conflict between the Myanmar military (Tatmadaw) and Arakan Army was reported in northern and central Rakhine State increasing from 6,000 people in February to 20,000 i
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n March. WFP delivered a one-month ration of food to 2,220 newly displaced people in central Rakhine State, with plans to extend support to additional displaced populations based on coordination with other actors meeting current needs, including the Government and ICRC. WFP continued providing emergency relief assistance to 96,050 conflict-affected people from 173 Muslim, Buddhist and Hindu villages in Buthidaung and Maungdaw townships of northern Rakhine State. In addition, WFP reached over 16,300 children under 5 years through nutrition interventions. In central Rakhine, 4,740 pregnant and lactating women (PLWs) and 24,160 children under 5 years were reached with nutrition interventions, and over 128,040 food-insecure people received relief assistance.
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This global guidance provided the framework for over 100 countries to develop their NDVPs. This updated (second) version supersedes the previous version published in 16 November 2020. New information has been added on the following areas:
the COVID-19 Partners Platform;
the use of COVID
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-19 simulation exercises to test deployment strategies;
the indemnity agreement and no-fault compensation programme for vaccines secured through the COVAX Facility in the Advance Market Commitment (AMC) eligible economies;
the availability and use of the WHO-UNICEF COVID-19 Vaccine Introduction and deployment Costing (CVIC) tool;
the COVAX Facility’s humanitarian buffer that enables allocation of vaccine to cover high-risk populations in humanitarian settings;
recommendations for vaccination of pregnant and lactating women;
supplementary information on infection prevention and control (IPC) measures to be used to deliver COVID-19 vaccines safely;
the WHO licensed COVID-19 vaccines product-specific information;
use of geospatial data and digital micro plans for equitable access and delivery of COVID-19 vaccines;
lessons learned from the development of NDVPs and early experiences in COVID-19 vaccine deployment in countries; and
updated additional resources at the end of each chapter.
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The UNICEF Syria webpage titled "Cholera Resource Material" offers a collection of educational resources aimed at preventing cholera and safeguarding families. These materials, available in Arabic, include posters and flyers on topics such as handwashing, water purification, recognizing cholera symp
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toms, prevention strategies, and specific guidance for pregnant and lactating women. The initiative emphasizes the importance of disseminating accurate information to effectively combat cholera outbreaks in Syria. By providing these resources, UNICEF aims to empower communities with the knowledge needed to protect themselves and their loved ones from cholera.
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Soil-transmitted helminth (STH) infections are among the most common infections worldwide with an estimated 1.5 billion infected people or 24% of the world’s population. These infections affect the poorest and most deprived communities with poor access to clean water, sanitation and hygiene in tro
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pical and subtropical areas, with the highest prevalence reported from sub-Saharan Africa, China, South America and Asia. They are transmitted by eggs present in human faeces, which in turn contaminate soil in areas where sanitation is poor. Over 260 million preschool-age children, 654 million school-age children,108 million adolescent girls and 138.8 million pregnant and lactating women live in areas where these parasites are intensively transmitted, and are in need of treatment and preventive interventions.
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The Roadmap towards ending TB among children and adolescents, third edition builds on the 2013 and 2018 versions. The 2023 version recognizes the progress made over the past five years and outlines priorities and key actions designed to accelerate progress towards the targets elaborated during the 2
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023 United Nations General Assembly High-Level Meeting on the fight against TB. Implementation of these key actions at the global, regional, national and sub-national levels is expected to find and treat more children and adolescents with tuberculosis (TB) disease or TB infection, to prevent TB, to improve treatment outcomes and prevent TB-associated disability. The 2023 Roadmap retains the strong focus on TB in children, while also emphasizing the importance of addressing TB among adolescents, and for the first time, among pregnant and post-partum women.
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What is high blood pressure in pregnancy?
Blood pressure is the force of your blood pushing against the walls of your arteries as your heart pumps blood. High blood pressure, or hypertension, is when this force against your artery walls is too high. There are different types of high blood pressure
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in pregnancy:
Gestational hypertension is high blood pressure that you develop while you are pregnant. It starts after you are 20 weeks pregnant. You usually don't have any other symptoms. In many cases, it does not harm you or your baby, and it goes away within 12 weeks after childbirth. But it does raise your risk of high blood pressure in the future. It sometimes can be severe, which may lead to low birth weight or preterm birth. Some women with gestational hypertension do go on to develop preeclampsia.
Chronic hypertension is high blood pressure that started before the 20th week of pregnancy or before you became pregnant. Some women may have had it long before becoming pregnant but didn't know it until they got their blood pressure checked at their prenatal visit. Sometimes chronic hypertension can also lead to preeclampsia.
Preeclampsia is a sudden increase in blood pressure after the 20th week of pregnancy. It usually happens in the last trimester. In rare cases, symptoms may not start until after delivery. This is called postpartum preeclampsia. Preeclampsia also includes signs of damage to some of your organs, such as your liver or kidney. The signs may include protein in the urine and very high blood pressure. Preeclampsia can be serious or even life-threatening for both you and your baby.
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The PDF "COLERA: Informação para Promotores de Saúde" provides essential guidance for health promoters and activists on cholera. It explains that cholera is characterized by severe watery diarrhea, often resembling rice water, and sometimes vomiting. If not treated promptly, it can lead to death
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within hours. The disease affects both adults and children and spreads through contaminated feces, poor hygiene, and unsafe water or food. To prevent cholera, the document emphasizes the importance of drinking treated or safe water, cooking food thoroughly and keeping it covered, washing hands with soap or ash after using the latrine and before handling food, and using proper latrines or sanitary facilities. It also highlights the role of vaccination, recommending the oral cholera vaccine "Shanchol," which requires two doses 2–3 weeks apart. The vaccine is suitable for individuals over one year old, including pregnant women, and has minimal side effects such as mild abdominal pain or diarrhea. This resource aims to empower health promoters with practical knowledge to prevent and manage cholera outbreaks effectively.
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Antimalarial chemotherapy is crucial for reducing morbidity, mortality, and drug resistance, and is the cornerstone of malaria control. Existing antimalarial drugs act at different stages of the parasite’s life cycle. These drugs range from classic agents such as chloroquine and quinine to newer a
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rtemisinin derivatives. They include tissue schizonticides, blood schizonticides, gametocytocides, and sporontocides. Artemisinin and its derivatives are the most effective and fastest-acting treatment against drug-resistant Plasmodium falciparum, achieving rapid parasite clearance and reducing transmission potential. Other key drugs include mefloquine, halofantrine, proguanil, sulfadoxine–pyrimethamine, atovaquone–proguanil, tetracyclines, clindamycin and azithromycin. Each of these drugs has a specific mechanism of action, pharmacokinetics, efficacy, safety profile and contraindications. Rational drug combinations and adherence to national treatment guidelines are essential for managing resistance, ensuring safety in vulnerable populations such as children and pregnant women, and optimising therapeutic outcomes in cases of both uncomplicated and severe malaria.
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Pregnant & HIV positive
(2018)
C1
BMC Pregnancy Childbirth 2022 Apr 5;22(1):284. doi: 10.1186/s12884-022-04619-w. Adolescent reproductive health is still a challenge in Low and Middle Income Come Countries (LMICs). However, the reasons for the inability of most pregnant adolescent
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girls to access and utilize maternal and child health information (MCHI) are not well-documented. This is despite the policy guidelines promoting the provision of this necessary information to pregnant adolescents in order to prepare them for delivery. This provision is one of the strategies envisaged to improve their attendance of ANC visits and their maternal and child health.
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Where Women Have No Doctor - Chapter 31 - Use of Medicines in Women’s Health
recommended
A. August Burns, Sandy Nieman, Elena Metcalf, Ronnie Lovich, Jane Maxwell, Katharine Shapiro
Hesperian Health Guides
(2014)
C1
This chapter talks about how to safely use the medicines mentioned in the book to treat women’s health problems. It also provides information to help decide when to use medicines to improve women
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s health.
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Chapter 29: Refugees and Displaced Women:
Flight and Arrival,
Basic Needs,
Reproductive Health,
Mental Health,
Women as Leaders
The “Right Start Initiative” is a comprehensive program reaching nine countries in Asia and Africa, designed and run by the Nutrition International with the goal of improving the quality of nutrition for 100 million adolescent girls and women of
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reproductive age.
more
Background Note: Briefing to the Executive Board, First Regular Session 2025
