Chagas disease caused by Trypanosoma cruzi is a public health issue in Latin America. This highly diverse parasite is divided into at least seven discrete typing units (DTUs) TcI-TcVI and Tcbat. Some DTUs have been associated with geographical distribution in epidemiological scenarios and clinical m...anifestations, but these aspects remain poorly understood. Many studies have focused on studying the parasite and its vectors/hosts, using a wide variety of genetic markers and methods. Here, we performed a systematic review of the literature for the last 20 years to present an update of DTUs distribution in the Americas, collecting ecoepidemiological information. We found that the DTUs are widespread across the continent and that there is a whole gamma of genetic markers used for the identification and genotyping of the parasite. The data obtained in this descriptor could improve the molecular epidemiology studies of Chagas disease in endemic regions.
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En el Plan estratégico de preparación y respuesta frente a la COVID-19, del 2021, la Organización Panamericana de la Salud invita a las autoridades nacionales a actualizar los planes nacionales para la COVID-19 a fin de incorporar las enseñanzas extraídas a lo largo del 2020, de prever los reto...s que habrá en el 2021 y de prepararse para ellos, incluida la preparación de todos los sistemas de salud para introducir de manera segura y equitativa nuevas herramientas para combatir la COVID-19, como las vacunas. En esta Orientación para la planificación operativa, que acompaña al plan estratégico de preparación y respuesta para el 2021, se proponen medidas prácticas de alto nivel en cada uno de los diez pilares de la preparación y la respuesta, que los países pueden adaptar según corresponda y ejecutar a escala nacional y subnacional para alcanzar los objetivos estratégicos del plan.
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This Toolkit is intended to guide humanitarian programme managers and healthcare providers to ensure that sexual and reproductive health interventions put into place both during and after a crisis are responsive to the unique needs of adolescents.
Trastornos de ansiedad
Capítulo F.1
Edición en español
Editor: Matías Irarrázaval
Traducción: Matías Irarrázaval y María Tatiana Estefan
Over 6 million people worldwide are infected with Trypanosoma cruzi, the protozoan that causes Chagas disease
(CD). T. cruzi is transmitted by triatomine insects, congenitally, through uncontrolled blood donations and organ transplants,
and via consumption of food or drink contaminated by triatomi...nes.
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Diagnóstico exploratorio sobre el tráfico y/o trata de personas con fines de explotación sexual
Consensual Recommendation for treatment of COVID-19 in older adults
The "Norma Técnica de Salud para la Atención integral de las Personas Afectadas por Tuberculosis" (Technical Health Standard for the Integral Care of Persons Affected by Tuberculosis)
incorporates important innovations that standardise the programmatic management of tuberculosis (TB).
The objective of the study was the validation and implementation of GeneXpert MTB/RIF for routine use in the rapid detection of tuberculosis and sensitivity to rifampicin in clinical samples; for this, 1592 respiratory samples were collected and analyzed in the laboratory of Instituto Nacional de In...vestigación en Salud Pública Guayaquil. The analysis of the results of GeneXpert in comparison with smear microscopy showed an initial sensitivity of 99.8% and specificity of 93.2%; The analysis of discrepancies using the results of the culture as a reference method showed that the GeneXpert results considered false negatives turned out to be true negatives, the same happens with the false positives that correspond to true positives. Recalculated the sensitivity and specificity of the GeneXpert was 99.8% and 100% correspondingly. The comparison with the drugs susceptibility test showed a sensitivity of 91.4% and a specificity of 95.5% for the GeneXpert MTB/RIF system. It is concluded that the implementation of the GeneXpert system allows solution to certain problems associated with the application of conventional diagnostic methodologies, decreasing the waiting times, and increasing the sensitivity and specificity in the diagnosis of drug-resistant tuberculosis, thus generating a valuable opportunity for early diagnosis.
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Misceláneo
Capítulo J.9
Edición: Matías Irarrázaval & Andres Martin
Revisión: Fernanda Prieto-Tagle & Paloma Varela
El esfuerzo por garantizar la dignidad y el bienestar de las mujeres que viven con VIH se centra en un enfoque integrado de la salud y los derechos humanos.
Manual para promotores/as, madres, padres y cuidadores/as | Parte del juego de herramientas de Prevención de CBM sobre Parálisis Cerebral