The "Integrated Management of Malaria Training – Health Worker’s Manual" is a practical guide developed by Uganda’s Ministry of Health to train healthcare workers at all levels in the effective diagnosis, treatment, prevention, and management of malaria. It aligns with national malaria treatme...nt guidelines and aims to improve the quality of care and reduce malaria-related illness and death. The manual covers key topics such as clinical assessment of fever, use of rapid diagnostic tests (RDTs), case management of uncomplicated and severe malaria, malaria in pregnancy, co-infections like HIV, as well as community engagement and proper documentation. It includes structured training sessions, case studies, and job aids designed to strengthen the skills of health workers in both public and private sectors, and to ensure standardized, evidence-based malaria care across the country.
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2nd edition. The purpose of this document is to present updated standardized protocols that P. falciparum-endemic countries can use to determine the prevalence of parasites with pfhrp2/3 gene deletions causing negative HRP2 RDT results among symptomatic falciparum patients. The findings should be us...ed to guide RDT selection; more specifically when to shift away from exclusive use of HRP2 to detect P. falciparum infections.
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Clinical Pharmacology: Advances and Applications, 2025:17 29–47
Preferred product characteristics and clinical development considerations
Tropical Medicine and Health (2023) 51:29
Fragile Beginnings. The Fragile Beginnings series examines the growing body of research on the unique vulnerabilities of children: in utero and at birth, during infancy and childhood and throughout adolescence. Its purpose is to enable evidence-based advocacy and action on children’s environmental... health
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This document outlines key health messages for children and their caregivers, with a focus on the prevention and early treatment of common illnesses. Topics covered include malaria, diarrhoea, malnutrition, respiratory infections, intestinal worms, HIV/AIDS and accident prevention. The importance of... insecticide-treated nets, oral rehydration salts (ORS), breastfeeding, immunisation, hygiene, access to clean water, deworming and emotional care for child development is also emphasised. The practical advice provided helps families to create safer and healthier environments, and to recognise when medical help is needed.
Accessed on 15/07/2025.
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The '100 Health Messages for Children to Learn & Share' is an educational resource developed by Children for Health. It is aimed at children aged 8–14, particularly young adolescents (aged 10–14), who often care for younger siblings. The set contains 100 simple, accurate and adaptable health mes...sages, with 10 messages on each of the following topics: Malaria, diarrhoea, nutrition, coughs and colds, intestinal worms, water and sanitation, immunisation, HIV and AIDS, accidents and injuries, and early childhood development. The messages have been reviewed by medical and education experts and are designed for use by parents, teachers and health workers in schools, homes, clinics and clubs. The resource encourages active learning through memorisation, discussion, and creative activities, empowering children to become health educators in their communities.
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This training module on malaria case management has been developed to support the staff involved in malaria control and elimination programmes in the effective organization of malaria diagnosis and case management services
Le Infezioni in Medicina, n. 1, 3-10, 2019
This publication provides guidance for planning country-specific programming to achieve the triple elimination of mother-to-child (or vertical) transmission of HIV, syphilis and hepatitis B virus. It is based on the WHO Triple Elimination Framework, which promotes an integrated, person-centred appro...ach to efficiently and holistically prevent transmission of these infections from mothers to their infants along four pillars.
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The new WHO guidelines provide clinical management recommendations for four of the most widespread arboviruses affecting humans: dengue, chikungunya, Zika, and yellow fever.
An integrated approach is vital, as these four diseases often present with similar symptoms, especially in the early stages... of infection, and multiple arboviruses may circulate simultaneously in certain regions. This makes clinical differentiation challenging, particularly where diagnostic testing is not readily available.
This guideline is available in online format on the MAGICapp platform
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The 2022 report reviews the global malaria diagnostics market and technological landscape to support Unitaid’s 2023–2027 strategy for quality malaria case management. The report highlights the stalled progress of malaria control efforts, the gaps in access to diagnostics and the public health im...plications of P. falciparum HRP2/3 gene deletions, which compromise the accuracy of the widely used HRP2-detecting rapid diagnostic tests (RDTs). The report analyses the malaria RDT market, noting supplier diversification, price trends and production shifts resulting from the pandemic. It also addresses the emerging point-of-care G6PD testing market, which is required to ensure the safe radical cure of P. vivax infections. It surveys technological innovation, including digital microscopy, hemozoin tests, nucleic acid detection and biosensors, while emphasising that RDTs and microscopy will remain the mainstay of case management in the near term. The report identifies market shortcomings, access barriers and opportunities to improve malaria case management and diagnostic coverage.
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This document provides technical guidance for manufacturers seeking World Health Organization (WHO) prequalification of in vitro diagnostic devices (IVDs) for malaria, with a focus on rapid diagnostic tests (RDTs) for symptomatic patients. It summarises the minimum performance requirements, includin...g analytical and clinical performance standards, and emphasises considerations relating to diverse specimen types, testing environments and user populations in low- and middle-income countries. The guidance is aligned with the criteria and prequalification processes of the WHO Global Malaria Programme, while clarifying that demonstration of clinical utility is outside the scope of prequalification.
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This document provides technical guidance for manufacturers seeking World Health Organization (WHO) prequalification of in vitro diagnostic devices (IVDs) for malaria, with a focus on rapid diagnostic tests (RDTs) for symptomatic patients. It summarises the minimum performance requirements, includin...g analytical and clinical performance standards, and emphasises considerations relating to diverse specimen types, testing environments and user populations in low- and middle-income countries. The guidance is aligned with the criteria and prequalification processes of the WHO Global Malaria Programme, while clarifying that demonstration of clinical utility is outside the scope of prequalification.
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20 YEARS OF STRATEGIC HIV AND PUBLIC HEALTH DATA . beThe completion of the 6th South African National HIV Prevalence, Incidence and Behaviour Survey (SABSSM) report, coincides with the celebration of 30 years of democracy in South Africa; and marks 20 years of conducting nationally representative ho...usehold-based surveys by the Human Sciences Research Council (HSRC), its collaborators and donors. Since its inception in 2002, the SABSSM series has emerged as one of the HSRC’s leading scientific contributions to the country’s HIV and AIDS response (1), providing essential data to monitor the HIV epidemic, the impact of the HIV program in South Africa, and to inform strategies for epidemic control in the National Strategic Plan for HIV, TB and STIs (NSP), now in its fifth edition. Using scientific evidence from SABSSM and other key sources, the NSP guides the country’s response, under the leadership of the South African AIDS Council (SANAC) and the National Department of Health (NDoH), with focus on equitable access to biomedical interventions, addressing the structural and social behavioural drivers of the epidemic, and targeting populations disproportionately affected by HIV; such as, black Africans, key populations and adolescent girls and young women (AGYW) aged 15–24 years (2).
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These Frequently Asked Questions (FAQs) have been developed by the Infant Feeding in Emergencies (IFE) Core Group Infectious Disease Working Group based on the most recent recommendations, collective knowledge and evidence on cholera. The FAQs also draw on infant and young child feeding (IYCF) recom...mendations from the World Health Organization (WHO) and the Infant Feeding in Emergencies Core Group (IFE CG). These FAQs are intended to provide answers to health workers and the public – including mothers who are breastfeeding or expressing milk – on breastfeeding during a cholera outbreak.
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Ces questions fréquemment posées (FAQs) ont été élaborées par le Groupe de travail sur les maladies infectieuses du Groupe l'alimentation central sur des nourrissons en situation d'urgence (IFE) en se basant sur les recommandations les plus récentes, les connaissances collectives et les donn...es probantes relatives au choléra. Les questions fréquemment posées (FAQs) s'appuient également sur les recommandations de l'Organisation mondiale de la santé (OMS) et du Groupe central sur l'alimentation des nourrissons en situation d'urgence (IFE CG) en matière d'alimentation des nourrissons et des jeunes enfants (IYCF). Ces FAQs ont pour objectif de fournir des réponses aux professionnels de santé ainsi qu’au grand public- y compris aux mères qui allaitent ou qui tirent leur lait- au sujet de l'allaitement maternel lors d'une épidémie de choléra.
Cesquestions fréquentesreflètent:
•Les preuves disponibles et les derniers outils de lutte contre le choléra du Groupe de travail mondial sur la lutte contre le choléra (2025) et de l'UNICEF (2013)
•Les effets protecteurs du lait maternel et de l'allaitement
•Les effets néfastes liés à l'utilisation inappropriée de substituts de lait maternel
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Essential medicines are those that satisfy the priority health care needs of a population. They are selected with due regard to disease prevalence and public health relevance, evidence of efficacy and safety and comparative cost-effectiveness. They are intended to be available in functioning health ...systems at all times, in appropriate dosage forms, of assured quality, and at prices individuals and health systems can afford.
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1 February 2021 to 31 January 2022