This Rapid Communication aims to inform national TB programmes and other stakeholders about the key implications of the latest evidence on the use of specific molecular assays as initial diagnostic tests of pulmonary and extrapulmonary TB and RR-TB, in adults and children.
Près de deux ans après la signature de l’Accord Politique pour la Paix et la Réconciliation (APPR), la population centrafricaine est toujours l’otage d’un environnement sécuritaire instable et imprévisible. La poursuite des conflits dans plusieurs zones du pays, les faiblesses structurell...es conjuguées aux effets socio-économiques de la pandémie de COVID-19 et aux effets dévastateurs des catastrophes naturelles ont plongé 2,8 millions de personnes dans une grande vulnérabilité. Sur ce total, 1,9 million connaissent des besoins humanitaires sévères, un chiffre inégalé depuis 5 ans qui traduit une détérioration du bien-être physique et mental et des conditions de vie des populations dans l’ensemble du pays.
more
The purpose of cancer screening tests is to detect pre-cancer or early-stage cancer in asymptomatic individuals so that timely diagnosis and early treatment can be offered, where this treatment can lead to better outcomes for some people.
The aim of a cancer screening programme is either to reduc...e mortality and morbidity in a population by early detection and early treatment of a cancer (for example, breast screening) or to reduce the incidence of a cancer by identifying and treating its precursors (such as cervical and colorectal screening).
This short guide is designed to be a quick reference that contains the important ideas about cancer screening. Readers should refer to other publications for comprehensive discussion and detailed guidance on cancer screening programmes.
more
Cardiovascular disease (CVD) is the leading cause of global deaths, with the majority occurring in low- and middle-income countries (LMIC). The primary and secondary prevention of CVD is suboptimal throughout the world, but the evidence-practice gaps are much more pronounced in LMIC. Barriers at the... patient, health-care provider, and health system level prevent the implementation of optimal primary and secondary prevention. Identification of the particular barriers that exist in resource-constrained settings is necessary to inform effective strategies to reduce the identified evidence-practice gaps. Furthermore, targeting modifiable factors that contribute most significantly to the global burden of CVD, including tobacco use, hypertension, and secondary prevention for CVD will lead to the biggest gains in mortality reduction. We review a select number of novel, resource-efficient strategies to reduce premature mortality from CVD, including: (1) effective measures for tobacco control; (2) implementation of simplified screening and management algorithms for those with or at risk of CVD, (3) increasing the availability and affordability of simplified and cost-effective treatment regimens including combination CVD preventive drug therapy, and (4) simplified delivery of health care through task-sharing (non-physician health workers) and optimizing self-management (treatment supporters). Developing and deploying systems of care that address barriers related to the above, will lead to substantial reductions in CVD and related mortality.
more
Guidelines on care, treatment and support for women living with HIV/AIDS and their children in resource-constrained settings
L’analyse des besoins humanitaires en Haïti a révélé que plus de 4,4 millions d’Haïtiens et d’Haïtiennes, soit environ 40% de la population, auront besoin d’une assistance humanitaire en 2021.