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PROGRAM DESCRIPTION: Course is designed to increase knowledge and develop competency in the management of patients suspected of infection with dengue virus.
Website last accessed on 31.03.2023
Dengue vaccine for 9 to 16 year old's with previous dengue infection.
The document is a pocket guide for establishing and operating a Cholera Treatment Center (CTC). It provides guidelines on selecting a location, triaging patients based on dehydration severity, infection co
...
ntrol measures, and ensuring sufficient medical supplies. The guide emphasizes maintaining hygiene, proper waste management, and security while offering detailed protocols for treating moderate and severe cases of cholera. It is intended to support healthcare workers in efficiently managing cholera outbreaks.
more
Healthcare-associated infections (HAI) are a significant burden globally, with millions of patients affected each year. These infections affect both high- and limited-resource healthcare settings, but in limited-resource settings, rates are approximately twice as high as high-resource settings (15 o
...
ut of every 100 patients versus 7 out of every 100 patients). Furthermore, rates of infections within certain patient populations are significantly higher in limited-resource settings, including surgical patients, patients in intensive-care units (ICU) and neonatal units. It is well documented that environmental contamination plays a role in the transmission of HAIs in healthcare settings. Therefore, environmental cleaning is a fundamental intervention for infection prevention and control (IPC).It is a multifaceted intervention that involves cleaning and disinfection (when indicated) of the environment alongside other key program elements to support successful implementation (e.g., leadership support, training, monitoring, and feedback mechanisms). To be effective, environmental cleaning activities must be implemented within the framework of the facility IPC program, and not as a standalone intervention. It is also essential that IPC programs advocate for and work with facility administration and government officials to budget, operate and maintain adequate water, sanitation and hygiene (WASH) infrastructure to ensure that environmental cleaning can be performed according to best practices.
more
Key messages for professionals working at hospitals and other healthcare settings: managers/administrators, infectious disease specialists, infection prevention and control professionals, epidemiolo
...
gists, prescribers, junior doctors and students, pharmacists, nurses, clinical microbiologists, and professionals in emergency departments, in intensive care units, and in long-term care facilities.
more
Manufacturing Facility Assessment Toolkit
recommended
Tools and resources for occupational safety and health professionals and state and local public health officials assessing manufacturing facilities.
Occupational safety and health professionals and state and local public health officials can use these tools to assess coronavirus disease 2019 (COVID
...
-19) infection prevention and control measures at manufacturing facilities, as well as these facilities’ overall hazard assessment and control plans
more
This document aims to present an algorithm for deciding whom to test and provide guidance on the laboratory tests for Zika virus infection diagnosis in order to support clinical diagnostic and case reporting through surveillance among EU Member Stat
...
es. The algorithm is not intended for clinical management of patients with suspected Zika virus infection.
The information is provisional and subject to revision when new information becomes available.
more
CDC’s Core Elements of Hospital Antibiotic Stewardship Programs suggests that pharmacists review antibiotic therapy that is unnecessarily duplicative, including the use of agents with overlapping spectra. The combination of two agents with anaerobic activity is unnecessary in most cases. Exception
...
s may include Clostridioides difficile infection, necrotizing fasciitis, and certain biliary infections.
more
March 2020
The number of African Union Member States reporting COVID-
19 cases is increasing and there is a likelihood of community transmission. The WHO recently modified the COVID-19 suspect case definition to include severe acute respiratory infection
...
and advises testing of all severe acute respiratory illness (SARI) cases.1 However, many Member States have not yet started implementing these changes, they are still focussing surveillance efforts on individuals with travel history to an area with local COVID-19 transmission. This means patients with similar symptoms, but no apparent contact, may not
be investigated.
more
Leishmaniasis is a vector-borne disease that is transmitted by sandflies and caused by obligate intracellular protozoa of the genus Leishmania. Human infection is caused by about 21 of 30 species that infect mammals. These include the L. donovani co
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mplex with 3 species (L. donovani, L. infantum, and L. chagasi); the L. mexicana complex with 3 main species (L. mexicana, L. amazonensis, and L. venezuelensis); L. tropica; L. major; L. aethiopica; and the subgenus Viannia with 4 main species (L. (V.) braziliensis, L. (V.) guyanensis, L. (V.) panamensis, and L. (V.) peruviana). The different species are morphologically indistinguishable, but they can be differentiated by isoenzyme analysis, molecular methods, or monoclonal antibodies.
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Leishmaniasis is a parasitic disease that is found in parts of the tropics, subtropics, and southern Europe. Leishmaniasis is caused by infection with Leishmania parasites, which are spread by the bite of infected sand flies. There are several diffe
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rent forms of leishmaniasis in people. The most common forms are cutaneous leishmaniasis, which causes skin sores, and visceral leishmaniasis, which affects several internal organs (usually spleen, liver, and bone marrow).
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Onchocerciasis, or river blindness, is a neglected tropical disease (NTD) caused by the parasitic worm Onchocerca volvulus. It is transmitted through repeated bites by blackflies of the genus Simulium. The disease is called river blindness because the blackfly that transmits the
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infection lives and breeds near fast-flowing streams and rivers, mostly near remote rural villages. The infection can result in visual impairment and sometimes blindness. Additionally, onchocerciasis can cause skin disease, including intense itching, rashes, or nodules under the skin. Worldwide onchocerciasis is second only to trachoma as an infectious cause of blindness.
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The term leishmaniasis encompasses multiple clinical syndromes, including the cutaneous, mucosal, and visceral forms, which result from infection of macrophages in the dermis, in the naso-orpharyngeal mucosa, and throughout the reticuloendothelial s
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ystem, respectively. The infection can range from asymptomatic to severe in all of these forms. Cutaneous and mucosal leishmaniasis can cause severe morbidity; visceral and mucosal leishmaniasis can be life threatening.
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Almost half of the world's population, about 4 billion people, live in areas with a risk of dengue. Anyone who lives in or travels to an area with risk of dengue is at risk for infection.Before you travel, find country-specific travel information to
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help you plan and pack.
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The aim of this handbook is to provide network members and other laboratories involved in the diagnosis of tuberculosis, with an agreed list of key diagnostic methods and their protocols in various areas of TB diagnosis, ranging from microbiological diagnosis of active TB to the diagnosis of latent
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TB infection. This handbook offers a single source of reference by compiling all methods, with a strong focus on standard (reference) and evidence-based methods. In so doing, it will also contribute to the improvement of disease surveillance data for Europe.
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The CDC Self-Study Modules on Tuberculosis are a series of nine educational modules divided into two courses. The first course (Modules 1–5) provides fundamental information about tuberculosis, while the second course (Modules 6–9) offers more specific program-related details. These modules are
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designed for healthcare providers and other professionals who want to expand their knowledge of tuberculosis through self-study.
The modules cover topics such as transmission, pathogenesis, epidemiology, targeted testing, diagnosis, treatment, infection control, patient management, patient rights, contact investigations, and outbreak response. Some modules also offer the opportunity to earn continuing education credits.
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Epidemic Preparedness and Response in Africa | Guidelines for the Decentralization of Laboratory Capacity
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The decentralization of laboratory capacities is a critical strategy for improving epidemic preparedness and response in Africa. Centralized systems often delay case confirmation, hinder timely interventions, and exacerbate the impact of outbreaks, especially in rural and hard-to-reach areas.
Thi
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s Guidelines outlines a structured approach to decentralization, focusing on:
Strategic Goals: Strengthening laboratory capacity at subnational levels to ensure timely detection and control of epidemic-prone diseases.
Guiding Principles: Equity, country ownership, multisectoral collaboration and evidence-based decision-making.
Implementation Framework: Practical steps for planning, executing, and sustaining decentralized diagnostic networks, with intra- and post-implementation reviews for continuous improvement.
Integration: Alignment with existing surveillance, case management and infection prevention and control (IPC) systems, with a focus on the One Health approach.
While the Guidelines is informed by the Mpox outbreak response, it is adaptable to other priority diseases and aligned with the International Health Regulations (IHR 2005), the Africa CDC Strategic Plan (2022-2027), and the WHO Health Security Framework.
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The objective of this document is to guide the preparation and implementation of national preparedness plans for the safety of substances of human origin during outbreaks of Zika virus infection, both in affected and non-affected areas.
Antibiotics only fight infections caused by bacteria. Like all drugs, they can be harmful and should only be used when necessary. Taking antibiotics when you have a virus can do more harm than good: you will still feel sick and the antibiotic could give you a skin rash, diarrhea, a yeast
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infection, or worse.
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Limited coverage of laboratory services and long turnaround times from real-time reverse transcription-polymerase chain reaction (rRT-PCR) for the detection of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has been insufficient to meet the demands in many African countries in response
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to the COVID-19 pandemic. Rapid antigen diagnostic tests (AgRDTs) are potentially useful as they can inform healthcare workers and individuals of their infection status at point-of-care testing
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