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Sleeping Sickness. A fight against a nightmarish disease

University of Glasgow and Wellcome Trust (2026) CC
Comic
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About Sleeping Sickness

Centers for disease control and prevention CDC (2025) C_CDC
Key facts
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Clinical Care of Human African Trypanosomiasis

Centers for disease control and prevention CDC (2025) C_CDC
Fact Sheet
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Clinical Guidance for Human African Trypanosomiasis

Centers for disease control and prevention CDC (2025) C_CDC
Fact Sheet
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Human African Trypanosomiasis

World Health Organization WHO, Regional Office of Africa (2025) C_WHO
Resource Platform
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African Trypanosomiasis Learning sheet

East African Regional External Quality Assessment Scheme (EA-REQAS) (2025) CC
Learning sheet no. 4 Accessed March, 2025
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Trypanosomiasis, African

Centers for disease control and prevention CDC (2025) C_CDC
DPDx Laboratory Identification of Parasites of Public Health Concerns Including Life cycle
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Human African trypanosomiasis (sleeping sickness) Cinical Guidelines

Médecines sans Frontièrs MSF (2025) C1
Chapter in Clinical guidelines -Diagnosis and Treatment manual
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What is sleeping sickness? 

Drugs for Neglected Diseases Intiative DNDi (2025) CC
Accessed March, 2025
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Number of new reported cases of human African trypanosomiasis (T.b. rhodesiense)

World Health Organization WHO (2025) C_WHO
The Global Health Observatory
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Number of reported cases of human African trypanosomiasis (T.b. gambiense)

World Health Organization WHO (2025) C_WHO
The Global Health Observatory
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New WHO guidelines for treating rhodesiense human African trypanosomiasis: expanded indications for fexinidazole and pentamidine
recommended

Lindner A. K.; V. Lejon, M.P. Barrett, et al. (2025) CC
The Lancet Infectious Disease Volume 25, Issue 2e77-e85February 2025
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Guidelines for the treatment of human African trypanosomiasis
recommended

World Health Organization WHO (2024) C_WHO
The present guidelines incorporate all these changes, leading to a substantial reconfiguration of therapeutic choices for both disease forms. HAT is a serious, life-threatening disease and the efficacy of fexinidazole depends on swallowing the medicine after an appropriate intake of food as well as... more
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Human African trypanosomiasis (sleeping sickness)

World Health Organization WHO (2024) C_WHO
Human African trypanosomiasis (HAT), or sleeping sickness, is caused by trypanosome parasites that are transmitted by tsetse flies. HAT is found only in sub-Saharan Africa. Two subspecies of Trypanosoma brucei cause disease: T. b. gambiense in West and Central Africa, and T. b. rhodesiense in East A... more
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Elimination of human African trypanosomiasis: The long last mile

Barrett MP, Priotto G, Franco JR, et al. (2024) CC
PLOS Neglected Tropical Diseases 18(5): e0012091. https://doi.org/10.1371/journal.pntd.0012091
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The elimination of human African trypanosomiasis: Monitoring progress towards the 2021–2030 WHO road map targets

Franco JR, Priotto G, Paone M, et al. (2024) CC
PLOS Neglected Tropical Diseases 18(4): e0012111. https://doi.org/10.1371/journal.pntd.0012111
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Evidence summary: systematic review of oral fexinidazole as first line treatment for rhodesiense Human African Trypanosomiasis

World Health Organization WHO (2024) C_WHO
Guidelines for the treatment of human African trypanosomiasis. Web Annex A. Commissioned by WHO Cochrane Response
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PICO questions, EtD tables, GDG recommendations

World Health Organization WHO (2024) C_WHO
WHO Guidelines for the Treatment of Human African Trypanosomiasis. Web Annex B
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Reported cases of acute African trypanosomiasis

Our World in Data (2024) CC
The number of reported cases of acute African trypanosomiasis (sleeping sickness). The disease is caused by parasitesthat are spread by tsetse flies and other insects. The disease is typically fatal if not treated.
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Report of the fifth WHO stakeholders meeting on gambiense and rhodesiense human African trypanosomiasis elimination

World Health Organization WHO (2023) C_WHO
WHO convened the fifth stakeholders meeting on the elimination of HAT due to infection with Trypanosoma brucei gambiense (g-HAT) and Trypanosoma brucei rhodesiense (r-HAT) in Geneva, Switzerland, on 7–9 June 2023. The meeting was held again in person after the coronavirus disease (COVID-19) pandem... more