MEDBOX | Toolbox One Health

One Health, Zero Deaths

Global Alliance for Rabies Control (2022) CC

World Rabies Day is the biggest event on the global rabies calendar, coordinated by GARC and it has been commemorated every year on September 28 – the anniversary of the death of Louis Pasteur – since 2007. World Rabies Day aims to raise awareness and advocate for rabies elimination globally. It is an event designed to be inclusive, uniting people, organizations, and stakeholders across all sectors against rabies – because together we can eliminate rabies! With this concept of togetherness and unity in mind, the theme for this year’s World Rabies Day is: Rabies: One Health, Zero Deaths

Tags: Rabies, Elimination, global, One Health, neglected tropical diseases,

Source: https://rabiesalliance.org/world-rabies-

Current Treatments to Control African Trypanosomiasis and One Health Perspective

Venturelli, A.; Tagliazucchi, L.; Lima, C.; Venuti, F. et al. MDPI Microorganisms (2022) CC

Human African Trypanosomiasis (HAT, sleeping sickness) and Animal African Trypanosomiasis (AAT) are neglected tropical diseases generally caused by the same etiological agent, Trypanosoma brucei. Despite important advances in the reduction or disappearance of HAT cases, AAT represents a risky reservoir of the infections. There is a strong need to control AAT, as is claimed by the European Commission in a recent document on the reservation of antimicrobials for human use. Control of AAT is considered part of the One Health approach established by the FAO program against African Trypanosomiasis. Under the umbrella of the One Health concepts, in this work, by analyzing the pharmacological properties of the therapeutic options against Trypanosoma brucei spp., we underline the need for clearer and more defined guidelines in the employment of drugs designed for HAT and AAT. Essential requirements are addressed to meet the challenge of drug use and drug resistance development. This approach shall avoid inter-species cross-resistance phenomena and retain drugs therapeutic activity

Tags: African Trypanosomiasis, HAT, Neglected Tropical Diseases (NTDs), OneHealth, challange, drug use, medication, infection,

Source: https://www.mdpi.com/2076-2607/10/7/1298

Framework for Environmental and Social Management

Food and Agriculture Organization of the United Nations FAO (2023) CC

The Food and Agriculture Organization of the United Nations (FAO) launched a new Framework for Environmental and Social Management (FESM) to ensure that both people and the environment are protected from any potential impacts of FAO programmes and projects. “This Framework ensures that our projects do both “no harm” and support the transformation to more efficient, more inclusive, more resilient and more sustainable agrifood systems by upholding the highest international standards for risk management,” FAO Director-General QU Dongyu explained during a virtual event. The Framework, which includes key elements of a people-centered approach and establishes environmental and social performance requirements for FAO programming, is also intended to ensure that all stakeholders, including local and indigenous communities, have ample opportunities to actively participate in projects’ activities and to voice their concerns about them

Tags: environmental health, planetary health, One Health, participation, Agriculture, food and nutrition,

Source: https://reliefweb.int/attachments/7cd10d

Chagas Disease: Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents with HIV

Panel on Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents with HIV Clinical Info HIV (2018) CC

Epidemiology Chagas disease (American trypanosomiasis) is caused by the protozoan parasite Trypanosoma cruzi, and transmitted to humans by infected triatomine bugs, and less commonly by transfusion, organ transplant, from mother to infant, and in rare instances, by ingestion of contaminated food or drink.1-4 The hematophagous triatomine vectors defecate during or immediately after feeding on a person. The parasite is present in large numbers in the feces of infected bugs, and enters the human body through the bite wound, or through the intact conjunctiva or other mucous membrane. Vector-borne transmission occurs only in the Americas, where an estimated 8 to 10 million people have Chagas disease.5 Historically, transmission occurred largely in rural areas in Latin America, where houses built of mud brick are vulnerable to colonization by the triatomine vectors.4 In such areas, Chagas disease usually is acquired in childhood. In the last several decades, successful vector control programs have substantially decreased transmission rates in much of Latin America, and large-scale migration has brought infected individuals to cities both within and outside of Latin America

Tags: Chagas, Epidemiology, diagnosis, Prevention, Treatment, HIV, adverse events, opportunistic infections, adults, Adolescents,

Source: https://clinicalinfo.hiv.gov/sites/defau

Antimicrobial Resistance (AMR)

Deininger, K. The MEDBOX Team (2023) CC

Issue Brief 31: Antimicrobial resistance (AMR) can occur when viruses, bacteria, parasites and fungi change over time. There is no longer a response to medicines, and the infection treatment gets really difficult which increases the risk of a disesase spread, which can lead to severe health problems. AMR is an increasing threat to global public health worldwide that requires cross-sectional and cross-disciplinary action. It is present in every country and is spurred by several human-made factors, including over- and/or inadequate use of antibiotics, poor hygiene and infection prevention control, and excessive usage of antibiotics outside the health care sector e.g. in life stock production

Tags: AMR, guidelines, resources, Antimicrobial resistance, key resources,

Source: https://medbox.org/dl/63dbaa0337a06f43c6

Chagas Disease in Dogs: Transmission, Diagnosis, Treatment, and Prevention

Saunders, A. & Hamer, S. Today's Veterinary Practice (2020) CC

Chagas disease is caused by Trypanosoma cruzi, a protozoal organism primarily transmitted by triatomine insect vectors, also known as “kissing bugs.” It is a zoonotic disease originally described by Brazilian physician Dr. Carlos Chagas in 1909 and is widespread in Latin America. Although triatomines and T. cruzi have long been endemic to the southern United States, awareness and identification of infected vectors and animals have recently increased throughout the United States. Canine Chagas disease can be acute or chronic and is predominantly characterized by inflammation and fibrosis of the heart, resulting in arrhythmias, myocardial dysfunction, heart failure, and sudden death, although many infected dogs are asymptomatic

Tags: Chagas, trypanosoma cruzi, Zoonotic diseases, veterinary diseases, transmission, diagnosis, treatment, Prevention, animal's health, animal's disease,

Source: https://todaysveterinarypractice.com/par

Prevalence and distribution of schistosomiasis in human, livestock, and snail populations in northern Senegal: a One Health epidemiological study of a multi-host system

Léger, E.; Borlase, A.; Fall, C. et al. The Lancet Planetary Health (2020) CC

Schistosomiasis is a neglected tropical disease of global medical and veterinary importance. As efforts to eliminate schistosomiasis as a public health problem and interrupt transmission gather momentum, the potential zoonotic risk posed by livestock Schistosoma species via viable hybridisation in sub-Saharan Africa have been largely overlooked. We aimed to investigate the prevalence, distribution, and multi-host, multiparasite transmission cycle of Haematobium group schistosomiasis in Senegal, West Africa

Tags: Schistosomiasis, neglected tropical diseases, Public health, sub-Saharan Africa, parasites, One Health,

Source: https://www.thelancet.com/action/showPdf

Sustainable food cold chains: Opportunities, challenges and the way forward

Food and Agriculture Organization of the United Nations FAO; United Nations Environment Programme UNEP Reliefweb OCHA Services (20022) CC

Amid food and climate crises, investing in sustainable food cold chains crucial - More than 3 billion people can’t afford a healthy diet - Lack of effective refrigeration directly results in the loss of 526 million tons of food production, or 12 percent of the global total - Developing countries could save 144 million tonnes of food annually if they reached the same level of food cold chain infrastructure as developed countrie

Tags: sustainable food, sustainability,

Source: https://reliefweb.int/report/world/susta

Global antimicrobial resistance and use surveillance system (‎GLASS)‎ report: 2022

World Health Organisation (WHO) (2022) C_WHO

The WHO Global Antimicrobial Resistance and Use Surveillance System (GLASS) was launched in 2015 to foster AMR surveillance and inform strategies to contain AMR. The system started with surveillance of AMR in bacteria causing common human infections and has expanded its scope to include surveillance of antimicrobial consumption (AMC), invasive fungal infections, and a One Health surveillance model relevant to human health. To meet future challenges, it is in continuous evolution to enhance the quality and representativeness of data to inform the AMR burden accurately. As of the end of 2022, 127 countries, territories and areas participate in GLASS. The fifth GLASS report, produced in collaboration with Member States, summarizes 2020 data on AMR rates in common bacteria from countries, territories, and areas. The report brings new features, including analyses of population testing coverage or AMR trends. For the first time, the report presents 2020 data on AMC at the national level. A new interactive dashboard allow users to explore AMR and AMC global data, country profiles and download the data. This report marks the end of the early implementation phase of GLASS. In addition to presenting data collected through the latest data call, this report provides a summary of five years of national AMR surveillance data contributed to GLASS from its initiation, presents AMR findings in the context of progress of country participation in GLASS and in global AMR surveillance coverage and laboratory quality assurance systems at (sub)national level. Patterns of antimicrobial consumption are presented by country with a particular focus on antibacterials. The report also presents the antimicrobial consumption according to the WHO AWaRe antibiotic classification, for penicillins and cephalosporines. From a One Health perspective, the report presents antimicrobial consumption data in the human sector expressed in tons to allow a comparison with antimicrobial consumption from other sectors (not included in this report)

Tags: AMR, One Health, antimicrobial,

Source: https://apps.who.int/iris/rest/bitstream

World Health Organization WHO (2022) C_WHO

The Quadripartite Organizations – the Food and Agriculture Organization of the United Nations (FAO), the United Nations Environment Programme (UNEP), the World Organisation for Animal Health (WOAH, founded as OIE), and the World Health Organization (WHO) – collaborate to drive the change and transformation required to mitigate the impact of current and future health challenges at the human–animal– plant–environment interface at global, regional and country level

Tags: One Health, environmental health, animal's health, plant protection,

Source: https://apps.who.int/iris/rest/bitstream

	One Health, Zero Deaths Global Alliance for Rabies Control (2022) CC Open external link (7) Add to my MEDBOX World Rabies Day is the biggest event on the global rabies calendar, coordinated by GARC and it has been commemorated every year on September 28 – the anniversary of the death of Louis Pasteur – since 2007. World Rabies Day aims to raise awareness and advocate for rabies elimination globally. It is an event designed to be inclusive, uniting people, organizations, and stakeholders across all sectors against rabies – because together we can eliminate rabies! With this concept of togetherness and unity in mind, the theme for this year’s World Rabies Day is: Rabies: One Health, Zero Deaths Tags: Rabies, Elimination, global, One Health, neglected tropical diseases, Source: https://rabiesalliance.org/world-rabies-
	Current Treatments to Control African Trypanosomiasis and One Health Perspective Venturelli, A.; Tagliazucchi, L.; Lima, C.; Venuti, F. et al. MDPI Microorganisms (2022) CC Open external link (27) Add to my MEDBOX Human African Trypanosomiasis (HAT, sleeping sickness) and Animal African Trypanosomiasis (AAT) are neglected tropical diseases generally caused by the same etiological agent, Trypanosoma brucei. Despite important advances in the reduction or disappearance of HAT cases, AAT represents a risky reservoir of the infections. There is a strong need to control AAT, as is claimed by the European Commission in a recent document on the reservation of antimicrobials for human use. Control of AAT is considered part of the One Health approach established by the FAO program against African Trypanosomiasis. Under the umbrella of the One Health concepts, in this work, by analyzing the pharmacological properties of the therapeutic options against Trypanosoma brucei spp., we underline the need for clearer and more defined guidelines in the employment of drugs designed for HAT and AAT. Essential requirements are addressed to meet the challenge of drug use and drug resistance development. This approach shall avoid inter-species cross-resistance phenomena and retain drugs therapeutic activity Tags: African Trypanosomiasis, HAT, Neglected Tropical Diseases (NTDs), OneHealth, challange, drug use, medication, infection, Source: https://www.mdpi.com/2076-2607/10/7/1298
	Framework for Environmental and Social Management Food and Agriculture Organization of the United Nations FAO (2023) CC Open external link (39) Add to my MEDBOX The Food and Agriculture Organization of the United Nations (FAO) launched a new Framework for Environmental and Social Management (FESM) to ensure that both people and the environment are protected from any potential impacts of FAO programmes and projects. “This Framework ensures that our projects do both “no harm” and support the transformation to more efficient, more inclusive, more resilient and more sustainable agrifood systems by upholding the highest international standards for risk management,” FAO Director-General QU Dongyu explained during a virtual event. The Framework, which includes key elements of a people-centered approach and establishes environmental and social performance requirements for FAO programming, is also intended to ensure that all stakeholders, including local and indigenous communities, have ample opportunities to actively participate in projects’ activities and to voice their concerns about them Tags: environmental health, planetary health, One Health, participation, Agriculture, food and nutrition, Source: https://reliefweb.int/attachments/7cd10d
	Chagas Disease: Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents with HIV Panel on Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents with HIV Clinical Info HIV (2018) CC View PDF(12) Download (7) Add to my MEDBOX Epidemiology Chagas disease (American trypanosomiasis) is caused by the protozoan parasite Trypanosoma cruzi, and transmitted to humans by infected triatomine bugs, and less commonly by transfusion, organ transplant, from mother to infant, and in rare instances, by ingestion of contaminated food or drink.1-4 The hematophagous triatomine vectors defecate during or immediately after feeding on a person. The parasite is present in large numbers in the feces of infected bugs, and enters the human body through the bite wound, or through the intact conjunctiva or other mucous membrane. Vector-borne transmission occurs only in the Americas, where an estimated 8 to 10 million people have Chagas disease.5 Historically, transmission occurred largely in rural areas in Latin America, where houses built of mud brick are vulnerable to colonization by the triatomine vectors.4 In such areas, Chagas disease usually is acquired in childhood. In the last several decades, successful vector control programs have substantially decreased transmission rates in much of Latin America, and large-scale migration has brought infected individuals to cities both within and outside of Latin America Tags: Chagas, Epidemiology, diagnosis, Prevention, Treatment, HIV, adverse events, opportunistic infections, adults, Adolescents, Source: https://clinicalinfo.hiv.gov/sites/defau
	Antimicrobial Resistance (AMR) Deininger, K. The MEDBOX Team (2023) CC View PDF(21) Download (31) Add to my MEDBOX Issue Brief 31: Antimicrobial resistance (AMR) can occur when viruses, bacteria, parasites and fungi change over time. There is no longer a response to medicines, and the infection treatment gets really difficult which increases the risk of a disesase spread, which can lead to severe health problems. AMR is an increasing threat to global public health worldwide that requires cross-sectional and cross-disciplinary action. It is present in every country and is spurred by several human-made factors, including over- and/or inadequate use of antibiotics, poor hygiene and infection prevention control, and excessive usage of antibiotics outside the health care sector e.g. in life stock production Tags: AMR, guidelines, resources, Antimicrobial resistance, key resources, Source: https://medbox.org/dl/63dbaa0337a06f43c6
	Chagas Disease in Dogs: Transmission, Diagnosis, Treatment, and Prevention Saunders, A. & Hamer, S. Today's Veterinary Practice (2020) CC Open external link (45) Add to my MEDBOX Chagas disease is caused by Trypanosoma cruzi, a protozoal organism primarily transmitted by triatomine insect vectors, also known as “kissing bugs.” It is a zoonotic disease originally described by Brazilian physician Dr. Carlos Chagas in 1909 and is widespread in Latin America. Although triatomines and T. cruzi have long been endemic to the southern United States, awareness and identification of infected vectors and animals have recently increased throughout the United States. Canine Chagas disease can be acute or chronic and is predominantly characterized by inflammation and fibrosis of the heart, resulting in arrhythmias, myocardial dysfunction, heart failure, and sudden death, although many infected dogs are asymptomatic Tags: Chagas, trypanosoma cruzi, Zoonotic diseases, veterinary diseases, transmission, diagnosis, treatment, Prevention, animal's health, animal's disease, Source: https://todaysveterinarypractice.com/par
	Prevalence and distribution of schistosomiasis in human, livestock, and snail populations in northern Senegal: a One Health epidemiological study of a multi-host system Léger, E.; Borlase, A.; Fall, C. et al. The Lancet Planetary Health (2020) CC Open external link (70) Add to my MEDBOX Schistosomiasis is a neglected tropical disease of global medical and veterinary importance. As efforts to eliminate schistosomiasis as a public health problem and interrupt transmission gather momentum, the potential zoonotic risk posed by livestock Schistosoma species via viable hybridisation in sub-Saharan Africa have been largely overlooked. We aimed to investigate the prevalence, distribution, and multi-host, multiparasite transmission cycle of Haematobium group schistosomiasis in Senegal, West Africa Tags: Schistosomiasis, neglected tropical diseases, Public health, sub-Saharan Africa, parasites, One Health, Source: https://www.thelancet.com/action/showPdf
	Sustainable food cold chains: Opportunities, challenges and the way forward Food and Agriculture Organization of the United Nations FAO; United Nations Environment Programme UNEP Reliefweb OCHA Services (20022) CC View PDF(18) Download (8) Add to my MEDBOX Amid food and climate crises, investing in sustainable food cold chains crucial - More than 3 billion people can’t afford a healthy diet - Lack of effective refrigeration directly results in the loss of 526 million tons of food production, or 12 percent of the global total - Developing countries could save 144 million tonnes of food annually if they reached the same level of food cold chain infrastructure as developed countrie Tags: sustainable food, sustainability, Source: https://reliefweb.int/report/world/susta
	Global antimicrobial resistance and use surveillance system (‎GLASS)‎ report: 2022 World Health Organisation (WHO) (2022) C_WHO View PDF(29) Download (9) Add to my MEDBOX The WHO Global Antimicrobial Resistance and Use Surveillance System (GLASS) was launched in 2015 to foster AMR surveillance and inform strategies to contain AMR. The system started with surveillance of AMR in bacteria causing common human infections and has expanded its scope to include surveillance of antimicrobial consumption (AMC), invasive fungal infections, and a One Health surveillance model relevant to human health. To meet future challenges, it is in continuous evolution to enhance the quality and representativeness of data to inform the AMR burden accurately. As of the end of 2022, 127 countries, territories and areas participate in GLASS. The fifth GLASS report, produced in collaboration with Member States, summarizes 2020 data on AMR rates in common bacteria from countries, territories, and areas. The report brings new features, including analyses of population testing coverage or AMR trends. For the first time, the report presents 2020 data on AMC at the national level. A new interactive dashboard allow users to explore AMR and AMC global data, country profiles and download the data. This report marks the end of the early implementation phase of GLASS. In addition to presenting data collected through the latest data call, this report provides a summary of five years of national AMR surveillance data contributed to GLASS from its initiation, presents AMR findings in the context of progress of country participation in GLASS and in global AMR surveillance coverage and laboratory quality assurance systems at (sub)national level. Patterns of antimicrobial consumption are presented by country with a particular focus on antibacterials. The report also presents the antimicrobial consumption according to the WHO AWaRe antibiotic classification, for penicillins and cephalosporines. From a One Health perspective, the report presents antimicrobial consumption data in the human sector expressed in tons to allow a comparison with antimicrobial consumption from other sectors (not included in this report) Tags: AMR, One Health, antimicrobial, Source: https://apps.who.int/iris/rest/bitstream
	One health joint plan of action (‎2022‒2026)‎: working together for the health of humans, animals, plants and the environment World Health Organization WHO (2022) C_WHO View PDF(39) Download (16) Add to my MEDBOX The Quadripartite Organizations – the Food and Agriculture Organization of the United Nations (FAO), the United Nations Environment Programme (UNEP), the World Organisation for Animal Health (WOAH, founded as OIE), and the World Health Organization (WHO) – collaborate to drive the change and transformation required to mitigate the impact of current and future health challenges at the human–animal– plant–environment interface at global, regional and country level Tags: One Health, environmental health, animal's health, plant protection, Source: https://apps.who.int/iris/rest/bitstream