Buruli ulcer (BU) is a skin-related neglected tropical disease (skin NTD) caused by infection with Mycobacterium ulcerans. BU is the third most common mycobacterial disease after tuberculosis and leprosy in people who are not immunocompromised. The infection manifests in non-ulcerative forms as nodules, plaques and/or oedemas, which ulcerate within 4–6 weeks and display characteristic undermined edges and yellowish-white necrotic slough . Most lesions occur on the lower limbs.