This policy brief highlights the importance of integrating a gender-sensitive approach in malaria control efforts worldwide. It presents evidence that addressing gender-specific vulnerabilities and needs—particularly of women and children—can yield a “double dividend” by improving health outcomes and advancing gender equality. The document advocates for targeted investments and strategies that consider social and biological gender factors to enhance the effectiveness of malaria interventions. It is intended for policymakers, donors, program implementers, and health stakeholders aiming to optimize malaria prevention and treatment through gender-responsive programming.