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1
La fiche d'information sur le choléra de l'Organisation mondiale de la santé fournit des informations essentielles sur le choléra, une infection diarrhéique aiguë causée par l'ingestion d'aliments ou d'eau contaminés par la bactérie Vibrio cholerae. La maladie reste une menace mondiale pour
...
la santé publique, en particulier dans les zones où l'accès à l'eau potable et à l'assainissement adéquat est insuffisant. Bien que de nombreuses personnes infectées présentent des symptômes légers ou inexistants, les cas graves peuvent entraîner une déshydratation rapide et la mort en l'absence de traitement. La prévention repose sur l'accès à une eau propre, un assainissement adéquat et de bonnes pratiques d'hygiène. Le traitement efficace consiste principalement en l'administration rapide de solutions de réhydratation orale. La fiche d'information met également en avant l'importance de la surveillance, de la préparation et des stratégies de réponse pour contrôler les épidémies.
more
The World Health Organization's cholera fact sheet provides essential information about cholera, an acute diarrheal infection caused by ingesting food or water contaminated with Vibrio cholerae bacteria. The disease remains a global public health threat, particularly in areas lacking safe water and
...
adequate sanitation. While many infected individuals exhibit mild or no symptoms, severe cases can lead to rapid dehydration and death if untreated. Prevention focuses on ensuring access to clean water, proper sanitation, and hygiene practices. Effective treatment primarily involves prompt administration of oral rehydration solutions. The fact sheet also highlights the importance of surveillance, preparedness, and response strategies to control outbreaks.
more
The technical note from the Global Task Force on Cholera Control (GTFCC) examines the risks and benefits of vaccinating pregnant women with WHO-prequalified oral cholera vaccines (OCVs) during mass vaccination campaigns. It highlights that three WHO-approved vaccines (Dukoral®, Shanchol™, and Euv
...
ichol®) offer sustained protection and a strong safety profile.
While these vaccines are not explicitly contraindicated for pregnant women, there is limited clinical data on their use during pregnancy. However, studies indicate that pregnant women with cholera face higher risks of fetal loss, stillbirth, and complications, especially if they experience severe dehydration. Some evidence suggests that vaccination can reduce cholera incidence in pregnant women and indirectly protect infants.
Although no controlled trials have focused on pregnant women, retrospective studies in Guinea and Zanzibar showed no significant increase in adverse pregnancy outcomes after OCV administration. The GTFCC concludes that the benefits of vaccination outweigh the risks, particularly in high-risk areas, and recommends including pregnant women in cholera vaccination campaigns while continuing to monitor safety data.
more
This manual summarizes the methodology used to develop WHODAS 2.0 and the findings obtained when the schedule was applied to certain areas of general health, including mental and neurological disorders.
The manual will be useful to any researcher or clinician wishing to use WHODAS 2.0 in their prac
...
tice. It includes the seven versions of WHODAS 2.0, which differ in length and intended mode of administration. It also provides general population norms; these allow WHODAS 2.0 values for certain subpopulations to be compared with those for the general population.
more
The provision of safe and efficacious blood and blood components for transfusion or manufacturing use involves a number of processes, from the selection of blood donors and the collection, processing and testing of blood donations to the testing of patient samples, the issue of compatible blood and
...
its administration to the patient. There is a risk of error in each process in this “transfusion chain” and a failure at any of these stages can have serious implications for the recipients of blood and blood products. Thus, while blood transfusion can be life-saving, there are associated risks, particularly the transmission of bloodborne infections.
Screening for transfusion-transmissible infections (TTIs) to exclude blood donations at risk of transmitting infection from donors to recipients is a critical part of the process of ensuring that transfusion is as safe as possible. Effective screening for evidence of the presence of the most common and dangerous TTIs can reduce the risk of transmission to very low levels. more
Screening for transfusion-transmissible infections (TTIs) to exclude blood donations at risk of transmitting infection from donors to recipients is a critical part of the process of ensuring that transfusion is as safe as possible. Effective screening for evidence of the presence of the most common and dangerous TTIs can reduce the risk of transmission to very low levels. more
La fourniture de sang et de produits sanguins sûrs et efficaces pour la transfusion ou la fabrication d’autres produits sanguins fait intervenir un certain nombre de processus, allant de la sélection des donneurs de sang et de la collecte, au traitement et au dépistage des dons de sang ainsi qu
...
’à l’analyse des échantillons des malades, à la délivrance de sang compatible et à son administration au patient. Il existe un risque d’erreur à chaque étape de la « chaîne de transfusion », et une défaillance à une quelconque de ces étapes peut avoir des conséquences graves pour les receveurs du sang ou des produits sanguins. Si la transfusion sanguine peut sauver des vies, elle comporte aussi des risques, en particulier la transmission des infections par le sang.
Le dépistage des infections transmissibles par transfusion (ITT) en vue d’exclure les dons de sang présentant un risque de transmettre une infection du donneur aux receveurs est une étape critique du processus visant à garantir au mieux la sécurité des transfusions. Un dépistage efficace des agents transmissibles par le sang les plus courants et les plus dangereux peut réduire le risque de transmission à des niveaux très faibles. more
Le dépistage des infections transmissibles par transfusion (ITT) en vue d’exclure les dons de sang présentant un risque de transmettre une infection du donneur aux receveurs est une étape critique du processus visant à garantir au mieux la sécurité des transfusions. Un dépistage efficace des agents transmissibles par le sang les plus courants et les plus dangereux peut réduire le risque de transmission à des niveaux très faibles. more
Flood Disaster Risk Management - Hydrological Forecasts: Requirements and Best Practices (Training Module)
Vogelbacher, A.
National Institute of Disaster Management (NIDM), Deutsche Gesellschaft für Internationale Zusammenarbeit (GIZ)
(2013)
C1
This Case Study explores flood forecasting systems from the perspective of its position within the flood warning process. A method for classifying the different approaches taken in flood forecasting is introduced before the elements of a present-day flood forecasting system are discussed in detail.
...
Finally, the state of the art in developing flood forecasting systems is addressed including how to deal with specific challenges posed.
The target group of this case study are decision makers in disaster risk management and/or water management. The case study should help to understand some hydrologic basics of the flood forecast and assist in the administration and implementation of an appropriate flood warning system in a specific environment, to find the best solution for a region.
Best solutions depend mainly on quality and availability of data, the areas and/or points of interest, catchment properties, cross border catchments, and financial capabilities with special consideration of flood forecast. more
The target group of this case study are decision makers in disaster risk management and/or water management. The case study should help to understand some hydrologic basics of the flood forecast and assist in the administration and implementation of an appropriate flood warning system in a specific environment, to find the best solution for a region.
Best solutions depend mainly on quality and availability of data, the areas and/or points of interest, catchment properties, cross border catchments, and financial capabilities with special consideration of flood forecast. more
Schistosomiasis is one of the 17 ‘neglected tropical diseases’ as classified by the World Health Organization.
In order to better understand attitudes and practices surrounding schistosomiasis, Malaria Consortium carried out a survey in Nampula province, Mozambique, where the organisation is i
...
mplementing a community engagement intervention with a
focus on this disease. Findings suggest a need for greater efforts to improve knowledge of schistosomiasis in affected communities
in order to increase uptake of mass drug administration and ensure that communities take appropriate measures to prevent infection.
more
The Infection Prevention and Control (IPC) Assessment Framework (IPCAF) is a tool to support the implementation of the World Health Organization (WHO) Guidelines on core components of IPC programmes at the acute health care facility level. The user should be familiar with the contents of these guide
...
lines, including the Interim practical manual supporting the implementation of the IPC core components at the facility level before using this tool. The IPCAF is a systematic tool that can provide a baseline assessment of the IPC programme and activities within a health care facility, as well as ongoing evaluations through repeated administration to document progress over time and facilitate improvement.
more
COMPENDIUM of health system responses to large-scale migration in the WHO European Region
recommended
The scale of international migration in the WHO European Region has increased substantially in the last decade. The dynamics of large-scale migration pose specific challenges and opportunities to health systems, and responses will differ from country to country. Strengthening health system responses
...
is one of the priority areas in the 2016 Strategy and action plan for refugee and migrant health in the WHO European Region. Its agreed actions include the identification and mapping of practices for developing and delivering health services that respond to the needs of refugees, asylum seekers and migrants. This compendium aims to collect and present some of these practices in the form of case studies. Selected in 2016, the case studies reflect experience from different levels of administration in a variety of European countries, and during the different phases of the migration journey.
more
Revised working paper following AVAREF meeting February 2019.
WHO has published a roadmap aiming to coordinate partners’ actions and contributions to the licensing and roll-out of Merck’s Ebola vaccine (VSV-ZEBOV) in African countries. The vaccine was developed during the West Africa Ebola epi
...
demic of 2014-2016, during which more than 11 000 people lost their lives to the disease. The vaccine was tested in European and African countries at the time and is currently used under an “expanded access” protocol in the Democratic Republic of Congo.
WHO will expedite prequalification and licensing of the vaccine for use in countries at risk of Ebola outbreaks and will coordinate work between those countries’ regulatory authorities and the European Medicines Agency and the US Food and Drug Administration.
more
Guide pratique de formation des relais communautaires et volontaires sur la Chimio prévention du Paludisme Saisonnier (CPS)
recommended
Prgramme national de lutte contre le paludisme, Senegal
Unicef, President's Malaria Initiative
(2015)
C2
Ce guide est destiné aux formateurs de distributeurs communautaires (relais, volontaires) de médicaments pour la chimio prévention du paludisme saisonnier. Il peut être utilisé par :
- Les responsables de programme de santé au niveau décentralisé : les Médecins-Chefs de région – Médec
...
ins Chefs de district
- Les responsables de PPS et encadreurs d’acteurs communautaires : Infirmiers Chefs de Poste – Responsable d’Organisation Communautaire
Cette formation a pour but de renforcer les capacités des relais communautaires dans l’administration des médicaments de la CPS lors des campagnes ciblées.
more
L’enseignement des soins infirmiers se fait sous la tutelle du ministère de la Santé et de la Prévention médicale.Il est en pleine effervescence,mais seulement avec deux niveaux de formation.
- En premier lieu,il y a la formation initiale qu’une seule institution nationale a assurée de 195
...
2 à 1992.Avec la pénurie de la main-d’œuvre et la libéralisation de l’éducation,le Sénégal fait face depuis une quinzaine d’années à l’ouverture effrénée d’écoles privées dont la majorité dispose d’un agrément du ministère de la Santé.Le diplôme requis à l’entrée dans ces institutions de formation est le baccalauréat de l’enseignement général (13 ans de scolarité).La durée des études est de trois années sanctionnées par un diplôme d’État d’infirmier délivré par le ministère de la Santé et de la Prévention médicale,pour les diplômés des secteurs public et privé. - En deuxième lieu,il y a la formation continue spécialisée,dans les huit filières suivantes:enseignement et administration,anesthésie et réanimation,kinésithérapie,biologie,imagerie médicale,odontologie,ophtalmologie et néphrologie.Elle est offerte sur une période de deux ans,par l’École nationale de développement sanitaire et social (ENDSS).Le profil de sortie permet aux soignants d’exercer leur profession spécialisée avec le diplôme de technicien supérieur de santé.
more
Development and Introduction of the Filariasis Test Strip: A New Diagnostic Test for the Global Program to Eliminate Lymphatic Filariasis
Pantelias, A.; King, J.D.; Lammie, P.; Weil, G.J.
The American Journal of Tropical Medicine and Hygiene
(2022)
CC
Am. J. Trop. Med. Hyg., 106 (Suppl 5), 2022, pp. 56–60. Lymphatic filariasis (LF) is a parasitic disease that is a major cause of chronic disability in the developing world. According to the 2021–2030 road map for neglected tropical diseases (NTDs) published by the World Health Organization (WHO
...
), the global goal for LF is elimination as a public health problem by 2030 through repeated rounds of mass drug administration (MDA). Critical components of any elimination program are monitoring and surveillance. Appropriate assessment tools and methods are needed for each stage of an elimination program; mapping to identify which areas require intervention, monitoring to assess the impact of interventions, and post-intervention surveillance to validate elimination or detect recrudescence.
more
COVID-19 vaccine tracker and landscape
recommended
The COVID-19 vaccine tracker and landscape compiles detailed information of each COVID-19 vaccine candidate in development by closely monitoring their progress through the pipeline.
The COVID-19 vaccine tracker:
Provides summary tables of COVID-19 vaccine candidates in both clinical and pre-
...
clinical development;
Provides analysis and visualization for several COVID-19 vaccine candidate categories;
Tracks the progress of each vaccine from pre-clinical, Phase 1, Phase 2 through to Phase 3 efficacy studies and including Phase 4 registered as interventional studies;
Provides links to published reports on safety, immunogenicity and efficacy data of the vaccine candidates;
Includes information on key attributes of each vaccine candidate and
Allows users to search for COVID-19 vaccines through various criteria such as vaccine platform, schedule of vaccination, route of administration, developer, trial phase and clinical endpoints.
The database is updated regularly - twice a week (Tuesday and Friday, 17:00 CET).
more
Africa Centers for Disease Control and Prevention (Africa CDC) is aware of the media releases of the preliminary results of a large randomized clinical trial conducted in the United Kingdom, which included dexamethasone, a corticosteroid, as one of the drugs used for the treatment of COVID-19 patien
...
ts. The investigators reported that administration of oral or injectable dexamethasone resulted in about one-third reduction in mortality among COVID-19 patientsi that required mechanical ventilation and about one-fifth for patients requiring oxygen.
more
WHO operational handbook on tuberculosis: module 4: treatment: tuberculosis care and support
recommended
The consolidated guidelines are complemented by an operational handbook which is designed to assist with implementation of the WHO recommendations by Member States, technical partners and others who are involved in the management of patients with DR-TB. The WHO Operational Handbook on Tuberculosis,
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Module 4: Treatment - Drug-Resistant Tuberculosis Treatment provides practical guidance on how to put in place the recommendations at the scale needed to achieve national and global impact.
The document provides information on different aspects of care and support for TB patients. In particular, the handbook provides practical guidance on the implementation of the interventions that enable treatment adherence such as social support, treatment administration options, digital adherence technologies. The practical guidance also includes models of care for all TB patients, models of care for children and adolescents, integrated care for TB, HIV and comorbidities, engagement of private sector, managing of TB in health emergencies. This new practical handbook also includes two important chapters on health education and counselling, and palliative care for patients with TB.
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Les Centres africains de contrôle et de prévention des maladies (Africa CDC) ont pris connaissance des communiqués de presse concernant les résultats préliminaires d'un vaste essai clinique randomisé mené au Royaume-Uni, qui incluait la dexaméthasone, un corticostéroïde, parmi les médicam
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ents utilisés pour le traitement des patients atteints de COVID-19. Les chercheurs ont rapporté que l'administration de dexaméthasone par voie orale ou injectable a permis de réduire d'environ un tiers la mortalité chez les patients COVID-19i qui nécessitaient une ventilation mécanique et d'environ un cinquième chez les patients nécessitant de l'oxygène. Depuis la publication de ces rapports médiatiques, les autorités sanitaires du Royaume-Uni et d'Afrique du Sud ont adopté la dexaméthasone pour le traitement des patients atteints de formes graves de COVID-19
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L’hémorragie du post-partum (HPP) est communément définie comme une perte
sanguine d’au moins 500 ml survenant dans les 24 heures qui suivent l’accouchement.
Elle est la première cause de mortalité maternelle dans les pays à revenu faible
et la cause principale de près d’un décès
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maternel sur quatre dans le monde. La plupart
des décès imputables à l’HPP surviennent pendant les premières 24 heures après
l’accouchement. La majorité d’entre eux pourraient être évités par l’administration
prophylactique d’utérotoniques au cours de la délivrance et une prise en charge
appropriée en temps opportun.
L’amélioration des soins aux femmes pendant l’accouchement en vue de prévenir
et traiter l’HPP est une étape essentielle vers la réalisation des objectifs du Millénaire
pour le développement. Ces recommandations ont donc pour objectif principal
de jeter les bases de l’élaboration de politiques et de programmes stratégiques
nécessaires pour garantir la mise en oeuvre pérenne d’interventions efficaces
en vue de réduire la charge mondiale de l’HPP.
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This document provides guidance on how to implement contact screening and chemoprophylaxis with single-dose rifampicin. The contents are logically ordered: counselling and obtaining consent, identification and listing of index case, listing of contacts, tracing of contacts, screening of contacts,
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administration of prophylactic drugs. Managerial aspects to undertake contact screeninig and chemoprophylaxis are also elaborated, including planning , training , supervision and drug management.
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