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Therapeutics and COVID-19 (Living Guideline, 10 November 2023)

World Health Organization WHO (2023) C_WHO

WHO has updated its guidelines for COVID-19 therapeutics, with revised recommendations for patients with non-severe COVID-19. This is the 13th update to these guidelines. Updated risk rates for hospital admission in patients with non-severe COVID-19 The guidance includes updated risk rates for... hospital admission in patients with non-severe COVID-19. The current COVID-19 virus variants tend to cause less severe disease while immunity levels are higher due to vaccination, leading to lower risks of severe illness and death for most patients. This update includes new baseline risk estimates for hospital admission in patients with non-severe COVID-19. The new ‘moderate risk’ category now includes people previously considered to be high risk including older people and/or those with chronic conditions, disabilities, and comorbidities of chronic disease. The updated risk estimates will assist healthcare professionals to identify individuals at high, moderate or low risk of hospital admission, and to tailor treatment according to WHO guidelines: **High: **People who are immunosuppressed remain at higher risk if they contract COVID-19, with an estimated hospitalization rate of 6%. **Moderate: **People over 65 years old, those with conditions like obesity, diabetes and/or chronic conditions including chronic obstructive pulmonary disease, kidney or liver disease, cancer, people with disabilities and those with comorbidities of chronic disease are at moderate risk, with an estimated hospitalization rate of 3%. Low: Those who are not in the high or moderate risk categories are at low risk of hospitalization (0.5%). Most people are low risk. Review of COVID-19 treatments for people with non-severe COVID-19 WHO continues to strongly recommend nirmatrelvir-ritonavir (also known by its brand name ‘Paxlovid’) for people at high-risk and moderate risk of hospitalization. The recommendations state that nirmatrelvir-ritonavir is considered the best choice for most eligible patients, given its therapeutic benefits, ease of administration and fewer concerns about potential harms. Nirmatrelvir-ritonavir was first recommended by WHO in April 2022. If nirmatrelvir-ritonavir is not available to patients at high-risk of hospitalization, WHO suggests the use of molnupiravir or remdesivir instead. WHO suggests against the use of molnupiravir and remdesivir for patients at moderate risk, judging the potential harms to outweigh the limited benefits in patients at moderate risk of hospital admission. For people at low risk of hospitalization, WHO does not recommend any antiviral therapy. Symptoms like fever and pain can continue to be managed with analgesics like paracetamol. WHO also recommends against use of a new antiviral (VV116) for patients, except in clinical trials. The update also includes a strong recommendation against the use of ivermectin for patients with non-severe COVID-19. WHO continues to advise that in patients with severe or critical COVID-19, ivermectin should only be used in clinical trials. more

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DHR-ICMR GUIDELINES FOR DIAGNOSIS AND MANAGEMENT OF RICKETTSIAL DISEASES IN INDIA

Indian Council of Medical Research (ICMR) (2015) C1

The present DHR-ICMR guidelines comprehensively address the various concerns regarding the clinical assessment, treatment, and laboratory diagnosis of rickettsial diseases in India and the world. It is hoped that physicians, health care workers, the scientific community, the regulatory agencies, pub... more

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IASC Guidelines for mental health and psychosocial support in emergency settings
recommended

Inter-Agency Standing Committee (2007) C1

Specific action sheets offer useful guidance on mental health and psychosocial support and cover the following areas coordination assessment monitoring and evaluation protection and human rights standards human resources community mobilisation and support health services education dissemination of i... more

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Policy options to mitigate a drop in fiscal space for health and HIV following the COVID-19 pandemic — Case studies from the Democratic Republic of the Congo, Jamaica and Lesotho, November 2020

UNAIDS (2021) CC

To assess the impact of the COVID-19 pandemic on health and HIV expenditure, UNAIDS carried out a modelling study on fiscal space for health and HIV. From a sample of 28 countries, three countries—the Democratic Republic of the Congo, Jamaica, and Lesotho—were selected to capture health and HIV ... more

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Vector control and the elimination of gambiense human African trypanosomiasis

World Health Organization WHO (2022) C_WHO

The main purpose of the meeting was to review tsetse control tools, activities and their contribution to the elimination of gHAT and the monitoring thereof. Seven endemic countries provided reports on recent and ongoing vector control interventions at the national level (Angola, Cameroon, Côte d’... more

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Census 2011 Profile of persons with disabilities | Statistics South Africa

Statistics South Africa (2014) CC

Stats SA has released an in-depth report on persons with disabilities. The report, written using Census 2011 data, is the first in a series of in-depth analyses of various Census 2011 variables, such as ageing and education. The report provides statistical evidence relating to the prevalence of dis... more

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Policy options to mitigate a drop in fiscal space for health and HIV following the COVID-19 pandemic — Case studies from DR Congo, Jamaica and Lesotho

UNAIDS UNAIDS (2021) CC

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SAM2020: An agenda for scaling-up the management of Severe Acute Malnutrition by 2020

Action Against Hunger (2015) C1

The agenda focuses on six critical changes necessary for more children suffering from SAM to access effective treatment. Building on lessons from the last decade, and the experiences of other successful health initiatives, the agenda addresses issues ranging from the creation of a more enabling envi... more

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Providing individualized peer support in mental health and related areas WHO QualityRights training to act, unite and empower for mental health (P I L O T V E R S I O N)

World Health Organization WHO (2017) C_WHO

This document has been developed to support countries develop and strengthen individualized peer support services in mental health and related areas. It addresses the provision of individualized peer support in the context of health services and the wider community.

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Out of the Shadows. Making Mental Health a Global Development Policy
recommended

Seth Mnookin World Bank Group, and World Health Organization WHO (2016) C_WHO

Mental disorders impose an enormous burden on society, accounting for almost one in three years lived with disability globally. •In addition to their health impact, mental disorders cause a significant economic burden due to lost economic output and the link between mental disorders and costly, po... more

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Tackling Antimicrobial Resistance

EuroHealth Observer European Observatory on Health Systems and Policies Eurostation (2020) C2

The focus of the current quarterly edition of Eurohealth (from the European Observatory on Health Systems and Policies) is Antimicrobial Resistance (AMR) and contains the following articles: • Strengthening implementation of AMR national action plans • Fostering clinical developmen... more

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Prevention and control of noncommunicable diseases in Turkey - The case for investment

Kontsevaya A, Farrington J, Balcılar M, Ergüder T World Health Organization (2018) C_WHO

Noncommunicable diseases (NCDs) such as cancer, cardiovascular diseases, diabetes and chronic respiratory diseases and their risk factors are an increasing public health and development challenge in Turkey. This report provides evidence through three analyses that NCDs reduce economic output, and di... more

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Financing Global Health 2013: Transition in an Age of Austerity

Institute for Health Metrics and Evaluation (2014) CC

Financing Global Health 2013: Transition in an Age of Austerity, IHME’s fifth annual report on global health expenditure, depicts financing trends that underline the resilience of development assistance for health. This year’s updated estimates show that despite lackluster economic growth and fi... more

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National Comprehensive HIV Prevention, Care, and Treatment Training for Pharmacy Professionals. Participant Manual

Ministry of Health, Federal Democratic Republic of Ethiopia Ministry of Health, Federal Democratic Republic of Ethiopia (2018) CC

In line with its decentralization principle, the Ethiopian Health Policy has achieved great progress in improving access to comprehensive HIV/AIDS services to the majority of the population. Both quality and coverage of services have improved significantlysince the initiation... more

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Water, Sanitation and Hygiene (WASH) in Schools: Guidelines for Timor-Leste, Vol. 1

República Democrática de Timor-Leste (2016) C1

The development of water, sanitation and hygiene (WASH) in schools guidelines for TimorLeste is a landmark moment in our quest to make every school child-friendly – a place where every child can learn, play and grow with pride and dignity. The overarching goal is to improve health, boost education... more

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Buruli ulcer : diagnosis of Mycobacterium ulcerans disease : a manual for health care providers

F. Portaels; Johnson, P.; Meyers, W. World Health Organization WHO (2001) CC

This manual is to assist health care providers and laboratory scientists to diagnose mycobacterium ulcerans disease (Buruli ulcer). The manual aims to achieve a better understanding of the clinical presentation and its diagnosis. The methods described are tailored to various levels of care and avail... more

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National Strategy for Containment of Antimicrobial Resistance in Turkmenistan

MINSITRY OF HEALTH AND MEDICAL INDUSTRY OF TURKMENISTAN (2018) C_WHO

Spread of resistance to antimicrobial agents (AMR) does not know national borders and has reached dimensions, which require immediate actions at the national, regional and global levels. Antibiotic resistance is a natural biological response to improper use of antimicrobial agents (AMA); increasing... more

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Practical Guide to Mental Health Problems
recommended

Sian Hawkins International Assistance Mission (2014) C2

This 88 page book is designed to help primary care workers understand mental health problems and how they can be treated. Mental health problems from childhood to old age are examined. The book focuses primarily on the Afghan culture but is also relevant to a wider community

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Guidance on global monitoring for diabetes prevention and control: Framework, indicators and application

World Health Organization WHO (2024) C_WHO

The Guidance on global monitoring for diabetes prevention and control by WHO provides a comprehensive framework to support countries in tracking and managing diabetes prevention, care, and outcomes. This document outlines indicators across 4 domains: health system determinants, service delivery, ris... more

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Air quality index annual update

Greenstone, M.; C. Hasenkopf and K. Lee University of Chicago’s Energy Policy Institute (2022) C1

During the first year of the Covid-19 pandemic, the world’s economy slowed. Yet, the global annual average particulate pollution (PM2.5) was largely unchanged from 2019 levels. At the same time, growing evidence shows air pollution—even when experienced at very low levels—hurts human health. T... more

IASC Guidelines for mental health and psychosocial support in emergency settings recommended

Out of the Shadows. Making Mental Health a Global Development Policy recommended

Practical Guide to Mental Health Problems recommended

IASC Guidelines for mental health and psychosocial support in emergency settings
recommended

Out of the Shadows. Making Mental Health a Global Development Policy
recommended

Practical Guide to Mental Health Problems
recommended