Patients with diabetes are at increased risk of developing cardiovascular disease (CVD) with its manifestations of coronary artery disease (CAD), heart failure (HF), atrial fibrillation (AF), and stroke, as well as aortic and peripheral artery diseases. In addition, diabetes is a major risk factor f...or developing chronic kidney disease (CKD), which in itself is associated with developing CVD. The combination of diabetes with these cardio-renal comorbidities enhances the risk not only for cardiovascular (CV) events but also for CV and all-cause mortality. The current European Society of Cardiology (ESC) Guidelines on the management of cardiovascular disease in patients with diabetes are designed to guide prevention and management of the manifestations of CVD in patients with diabetes based on data published until end of January 2023. Over the last decade, the results of various large cardiovascular outcome trials (CVOTs) in patients with diabetes at high CV risk with novel glucose- lowering agents, such as sodium–glucose co-transporter-2 (SGLT2) inhibitors and glucagon-like peptide-1 (GLP-1) receptor agonists (RAs), but also novel non-steroidal mineralocorticoid receptor antagonists (MRAs), such as finerenone have substantially expanded available therapeutic op-
tions, leading to numerous evidence-based recommendations for the management of this patient population.
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The report discusses the epidemiological and social aspects of ageing, health and functional changes experienced with ageing, the impact of physical activity, assessment of the nutritional status of older persons, and nutritional guidelines for healthy ageing.
PSYCHOLOGICAL HELP FOR ADULTS IN COMMUNITIES EXPOSED TO ADVERSITY
Early Identification and Early Intervention Services for Young Children with Developmental Delays and Disabilities in Namibia Republic of Namibia Namibia
Regional Consultations Report
front cover © Hannah Maule-Ffinch/Save the Children
A practical handbook covering the architecture, engineering, design and operation of prisons. It is intended for all ICRC delegates working in places of detention, whether they have extensive practical experience or are new to the field.
The report offers an analysis of the broader challenges to securing humanitarian action and recommends areas for improvement. This study will contribute to improving the way humanitarians ‘do business’ in complex
security environments. Document also available in French, Arabic and Spanish.
Mapping actions of nongovernmental organizations and other international development organizations
This toolkit will help you to plan and run an event that helps to change the way that people in your community think about, and behave towards, people with mental health problems
The Democratic Republic of the Congo (DRC) is one of the most complex and long-standing humanitarian crises in Africa. By the end of 2020, some 940,421 Congolese refugees and asylum seekers were hosted across the African continent. Ongoing conflicts in eastern DRC, as well as intercommunal violence,... continue to cause forced displacement within the DRC and into neighbouring countries, along with tragic loss of human life and destruction of communities.
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It aims to enable participants to:
know more about reactions to distress
know what psychological first aid is and what it is not
understand the three action principles of ‘Look, Listen and Link’
have practised providing PFA to someone in distress
have considered comple...x reactions and situations
be aware of the importance of self-care when helping others.
This training module is one of four on psychological first aid, which accompany a set of materials on psychological first aid
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In the present study, the Office of the United Nations High Commissioner for Human Rights sets forth the standards on equality and non discrimination of persons with disabilities under article 5 of the Convention on the Rights of Persons with Disabilities. It aims at providing guidance for implement...ation of article 5 of the Convention, identifying good practices and making recommendations.
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4th edition
The WHO Laboratory Biosafety Manual (LBM) has been in broad use at all levels of clinical and public health laboratories, and other biomedical sectors globally, serving as a de facto global standard that presents best practices and sets trends in biosafety.
LBM encouraged countries t...o accept and implement basic concepts in biological safety and to develop national codes of practice for the safe handling of biological agents in laboratories within their geographical borders.
This fourth edition of the manual builds on the risk assessment framework introduced in the third edition. A thorough, evidence-based and transparent assessment of the risks allows safety measures to be balanced with the actual risk of working with biological agents on a case-by-case basis.
This novel evidence- and risk-based approach will allow optimised resource use and sustainable laboratory biosafety and biosecurity policies and practices that are relevant to their individual circumstances and priorities, enabling equitable access to clinical and public health laboratory tests and biomedical research opportunities without compromising safety.
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