Lancet. 2019; 394: 1212-1214
Mpox is an emerging zoonotic disease caused by the mpox virus, a member of the Orthopoxvirus genus closely related to the variola virus that causes smallpox. Mpox was first discovered in 1958 when outbreaks of a pox-like disease occurred in monkeys kept for research. The first human case was recorde...d in 1970 in the Democratic Republic of the Congo (DRC) during a period of intensified effort to eliminate smallpox and since then the infection has been reported in a number of African countries. Mpox can spread in humans through close contact, usually skin-to-skin contact, including sexual contact, with an infected person or animal, as well as with materials contaminated with the virus such as clothing, beddings and towels, and respiratory droplets in prolonged face to face contact. People remain infectious from the onset of symptoms until all the lesions have scabbed and healed. The virus may spread from infected animals through handling infected meat or through bites or scratches. Diagnosis is confirmed by polymerase chain reaction (PCR) testing of material from a lesion for the virus’s DNA. Two separate clades of the mpox virus are currently circulating in Africa: Clade I, which includes subclades Ia and Ib, and Clade II, comprising subclades IIa and IIb. Clade Ia and Clade Ib have been associated with ongoing human-to-human transmission and are presently responsible for outbreaks in the Democratic Republic of the Congo (DRC), while Clade Ib is also contributing to outbreaks in Burundi and other countries.
In 2022‒2023 mpox caused a global outbreak in over 110 countries, most of which had no previous history of the disease, primarily driven by human-to-human transmission of clade II through sexual contact. In just over a year, over 90,000 cases and 150 deaths were reported to the WHO. For the second time since 2022, mpox has been declared a global health emergency as the virus spreads rapidly across the African continent. On 13 Aug 2024, Africa CDC declared the ongoing mpox outbreak a Public Health Emergency of Continental Security (PHECS), marking the first such declaration by the agency since its inception in 2017.7 This declaration empowered the Africa CDC to lead and coordinate responses to the mpox outbreak across affected African countries. On August 14, 2024, the WHO declared the resurgence of mpox a Public Health Emergency of International Concern (PHEIC) emphasizing the need for coordinated international response.
As of August 2024, Mpox has expanded beyond its traditional endemic regions, with new cases reported in countries including Sweden, Thailand, the Philippines, and Pakistan. Sweden has confirmed its first case of Clade 1 variant, which has been rapidly spreading in Africa, particularly in DRC. The emergence of this new variant raises concerns about its potential for higher lethality and transmission rates outside Africa.
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Nationally, Senegal met the MDG target for water supply access. It did this by engaging the public and private sectors to effectively invest and report on investments. It focused on larger population centers, less on remote regions of the country. Its achievements set the stage for more equitable an...d widespread service provision as the country now works to achieve the SDGs, requiring sustainable management of universal access. This case study documents the progression of the sector between 1990 and 2015, and analyzes the impact of local systems created in Senegal to respond to the water and sanitation challenge.
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Manual for step-by-step risk management for safely managed sanitation systems. 2nd edition.
This Sanitation safety planning (SSP) manual provides practical, step-by-step guidance to assist in the implementation of the 2018 World Health Organization (WHO) Guidelines on sanitation and health and the ...2006 WHO Guidelines for safe use of wastewater, excreta and greywater in agriculture and aquaculture. The approach and tools should be applied to all sanitary systems to ensure that they are managed to meet health objectives.
The SSP manual is targeted at a variety of users at different levels including; health authorities and regulators, local authorities, sanitation utility managers, sanitation enterprises and farmers, community-based organizations, farmers associations and nongovernmental organizations.
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Front. Public Health, 30 April 2021 | https://doi.org/10.3389/fpubh.2021.628744
Rapport spécial du GIEC sur le changement climatique,
la désertification, la dégradation des sols, la gestion durable
des terres, la sécurité alimentaire et les flux de gaz à effet de
serre dans les écosystèmes terrestres
The WHO Quality Toolkit: Navigating tools to improve the quality of health services helps easy identification and access to a wide range of WHO published materials to improve the quality of health services. These tools support the actions described in the Quality health services: a planning guide, w...hich outlines a structured, systems-based approach to improving quality of health services. Whether you work at the facility, sub-national or national level, or in specific communities, you will find resources within the Quality Toolkit to help you carry out essential tasks to improve quality of care
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The State of the world’s nursing 2020 report provides the latest, most up-to-date evidence on and policy options for the global nursing workforce.
This document should be used in conjunction with the WHO checklist for influenza preparedness planning published by the World Health Organization in 2005. Available in English; Chinese; French
Updated 6 September 2016. This guidance has been developed to provide advice on the prevention of potential sexual transmission of Zika virus. The primary transmission route of Zika virus is via the Aedes mosquito. However, sexual transmission of Zika virus may also be possible, with limited evidenc...e recorded in a few cases. This is of concern due to an association between Zika virus infection and potential complications, including microcephaly and Guillain-Barré syndrome.
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This document has been developed to support countries develop and strengthen individualized peer support services in mental health and related areas. It addresses the provision of individualized peer support in the context of health services and the wider community.
16-17 march 2015, Geneva, Switzerland
Meeting report
This report brings attention to achieving gender equality in the context of women, girls, and the HIV response. This six-month consultation in 2016 with adolescent women and young girls found that #WhatWomenWant is: collaboration and joint action by all to invest in women's HIV and Sexual and Reprod...uctive Health and Rights (SRHR), to be leaders and articulate the priorities of women and girls in all their diversity, and to speak to the new Political Declaration on AIDS and the SDG framework as a tool for civil society to meet their agenda to achieve gender equality in the HIV and SRHR response.
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As of June 2019, the number of Venezuelans leaving their country reached 4 million, with Colombia, Peru, Chile, Ecuador and Brazil hosting the vast majority of Venezuelans in Latin America. The end of the first half of the year was marked by the announcement of tighter immigration measures in Peru ...and Chile, which triggered a significant peak in flows from Venezuela entering Colombia, Ecuador and Peru. In response to this, UNICEF Country Offices activated contingency measures and capacities for registration and provision of services were rapidly increased, in coordination with relevant authorities, to face the increased demand.
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Faciliter l’accès aux soins de santé primaires et assurer une couverture sanitaire universelle à la population reste un défi de grande taille pour les pays en voie de développement. En effet malgré quelques efforts consentis ces dernières décennies, le problème d’accessibilité aux so...ins de santé est loin d’être résolu. Outre le problème épineux des ressources humaines s’ajoutent des difficultés liées à l’organisation et au fonctionnement des systèmes de santé, au financement des systèmes de santé, à la prestations de soins de qualité et à l’accès aux médicaments de base. Tous ceci ayant un impact désastreux sur la population notamment les plus pauvres qui n’arrivent plus à bénéficier de soins de qualité permettant d’obtenir une santé optimale.
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Conflict, climate change, the COVID-19 pandemic, and the economic effects of the Ukraine crisis are interacting to create new and worsen existing hunger hotspots, reversing the gains families had made to escape poverty.
This report provides a synthesis of some of the most recent, high-quality literature on the security and political processes in Central African Republic produced up to the end of January 2016. It was prepared for the European Union’s Instrument Contributing to Stability and Peace, © European Unio...n 2016. The views expressed in this report are those of the author, and do not necessarily reflect the opinions of GSDRC, its partner agencies or the European Commission. This is the second review published by GSDRC on the situation in the Central African Republic. The first review of literature was published in June 2013 and provides a country analysis covering the period 2003-2013. It is available at: http://www.gsdrc.org/docs/open/car_gsdrc2013.pdf.
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