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Government policy interventions to reduce human antimicrobial use: A systematic review and evidence map

Van Katwyk, S. R.; Grimshaw, J. M.; et al (2019) C2

BACKGROUND: Growing political attention to antimicrobial resistance (AMR) offers a rare opportunity for achieving meaningful action. Many governments have developed national AMR action plans, but most have not yet implemented policy interventions to reduce antimicrobial overuse. A systematic evidenc...e map can support governments in making evidence-informed decisions about implementing programs to reduce AMR, by identifying, describing, and assessing the full range of evaluated government policy options to reduce antimicrobial use in humans. METHODS AND FINDINGS: Seven databases were searched from inception to January 28, 2019, (MEDLINE, CINAHL, EMBASE, PAIS Index, Cochrane Central Register of Controlled Trials, Web of Science, and PubMed). We identified studies that (1) clearly described a government policy intervention aimed at reducing human antimicrobial use, and (2) applied a quantitative design to measure the impact. We found 69 unique evaluations of government policy interventions carried out across 4 of the 6 WHO regions. These evaluations included randomized controlled trials (n = 4), non-randomized controlled trials (n = 3), controlled before-and-after designs (n = 7), interrupted time series designs (n = 25), uncontrolled before-and-after designs (n = 18), descriptive designs (n = 10), and cohort designs (n = 2). From these we identified 17 unique policy options for governments to reduce the human use of antimicrobials. Many studies evaluated public awareness campaigns (n = 17) and antimicrobial guidelines (n = 13); however, others offered different policy options such as professional regulation, restricted reimbursement, pay for performance, and prescription requirements. Identifying these policies can inform the development of future policies and evaluations in different contexts and health systems. Limitations of our study include the possible omission of unpublished initiatives, and that policies not evaluated with respect to antimicrobial use have not been captured in this review. CONCLUSIONS: To our knowledge this is the first study to provide policy makers with synthesized evidence on specific government policy interventions addressing AMR. In the future, governments should ensure that AMR policy interventions are evaluated using rigorous study designs and that study results are published. more

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Multisectoral prioritization of zoonotic diseases in Uganda, 2017: A One Health perspective

Sekamatte, M.; V. Krishnasamy, L.Bulage et al. PLOS journals (2018) CC

PlosOne https://doi.org/10.1371/journal.pone.0196799; Zoonotic diseases continue to be a public health burden globally. Uganda is especially vulnerable due to its location, biodiversity, and population. Given these concerns, the Ugandan government in collaboration with the Global Health Security Age... more

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Late presentation of HIV infection in the country of Georgia: 2012-2015

N. Chkhartishvili; O. Chokoshvili; N. Bolokadze, et al. PLOS ONE; Georgios Nikolopoulos, University of Cyprus (2017) CC

PLOS ONE | https://doi.org/10.1371/journal.pone.0186835 October 30, 2017

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The future of WHO Covid-19 response operations in Africa in 2022
recommended

World Health Organization WHO, Regional Office of Africa (2022) C_WHO

The African Region has been experiencing unprecedented health challenges due to the Coronavirus disease 2019 (COVID-19) pandemic, which have compounded the already difficult task the Region was facing in moving towards universal health coverage (UHC) attainment.

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Characteristics and Treatment Outcomes of Retreatment Tuberculosis Patients in Benin

Serge Ade, Omer Adjibodé, Prudence Wachinou, Narcisse Toundoh, Bérénice Awanou, Gildas Agodokpessi, Dissou Affolabi, Gabriel Adè, Anthony D. Harries, Séverin Anagonou Hindawi (2016) C2

Patients with retreatment tuberculosis (TB) represent those who have been treated previously for onemonth ormorewith anti-TB drugs and who have been diagnosed once again with the disease.These patientsmainly include relapses, treatment after failure, or loss to follow-up on a first-line treatmen... more

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Improving Mental Well-Being and Productivity of Small-Medium Entrepreneurs in Fragile, Conflict and Violence Affected Areas

Saraf, P.; T. Rahman; M. Gallardo, et al. (2018) C1

This literature review summarizes the link between psychological well-being and entrepreneurial outcomes for small and medium-size enterprises in fragile, conflict, and violence–affected contexts. It identifies potentially promising, scalable psychosocial training interventions, based on cognitive... more

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Community-managed disaster risk reduction in fragile and conflict affected areas

Cordaid (2019) C1

Bridging the gap between disaster resilience and conflict risk reduction

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Americas: Population Movement Emergency Appeal n° MDR42004 - Operations Update no. 1, 1 February 2019

International Federation of Red Cross And Red Crescent Societies IFRC (2019)

By December of 2019, an estimated 5.3 million Venezuelans would have left the country, migrating in search of opportunities, health services and an overall search to improve the socio-economic conditions of themselves and their families. This is the largest migration in the history of the Americas. ... more

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Ebola Virus Disease Emergency Appeals (Guinea, Liberia, Sierra Leone and Global Coordination & Preparedness): Combined Ebola Operations Update No°24

International Federation of Red Cross And Red Crescent Societies (2015)

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National Strategic Plan on HIV and AIDS Myanmar 2016-2020

Myanmar, Ministry of Health and Sports (2017) C1

The Republic of the Union of Myanmar’s National Strategic Plan on HIV/AIDS 2016–2020 is the strategic guide for the country’s response to HIV at national, state/regional and local levels. The framework describes the current dynamics of the HIV epidemic and articulates a strategy to optimize in... more

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Africa - Ebola Coordination and Preparedness, Revised Emergency Appeal MDR60002
recommended

International Federation of Red Cross And Red Crescent Societies (2016) C1

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Malawi Floods: Emergency Plan of Action (EPoA) - DREF: MDRMW014 ( update n° 1: 01 April 2019)

International Federation of Red Cross And Red Crescent Societies IFRC (2019) C1

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Landmine Monitor 2017

International Campaign to Ban Landmines – Cluster Munition Coalition (ICBL-CMC) (2017) C3

This is the 19th annual Landmine Monitor report. It is the sister publication to the Cluster Munition Monitor report, first published in November 2010. Landmine Monitor 2016 provides a global overview of the landmine situation. Chapters on developments in specific countries and other areas are ava... more

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Health Sector Quality Improvement framework and strategic plan 2010/11 - 2014/15

Ministry of Health, Uganda (2011) C1

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An analysis of funding patterns in development assistance for mental health: who, when, what, and where

Gribble RSF, Liese BH, Wickremsinhe MN Global Mental Health (2021) C1

Background: Mental health has recently gained increasing attention on global health and development agendas, including calls for an increase in international funding. Few studies have previously characterized official development assistance for mental health (DAMH) in a nuanced and differentiated ma... more

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Permagarden Technical Manual

USAID; TOPS; Mercy Corps (2017) CC

2nd edition. This Permagarden Technical Manual is a resource for agriculture project staff implementing home garden projects with farmers. The manual explains how the permagarden method addresses soil health, water management and crop protection to create a year-round productive home garden. It incl... more

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Risk factors of Cholera mortality

Global Task Force On Cholera Control (GTFCC) (2022) CC

To better adapt current case management practices and address excess mortality in otherwise treatable cases will require better knowledge of the demographic characteristics of the patients and comorbidities which can make severe dehydration harder to tolerate physiologically. With this in mind, a ... more