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Operational manual on indoor residual spraying: Control of vectors of malaria, Aedes-borne diseases, Chagas disease, leishmaniases and lymphatic filariasis
recommended

World Health Organization WHO (2024) C_WHO

Indoor residual spraying (IRS) involves applying residual insecticide to potential vector resting sites on the interior surfaces of human dwellings or other buildings. The main aim of IRS is to kill vectors before they are able to transmit pathogens to humans. When carried out correctly, IRS has his... more

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Bench Aids for the diagnosis of filarial infections
recommended

World Health Organization WHO (1997) C_WHO

The Alere Filariasis Test Strip (FTS) is a rapid diagnostic test recommended for mapping, monitoring and transmission assessment surveys (TAS) for the qualitative detection of Wuchereria bancrofti antigen in human blood samples. The FTS has replaced the Binax Now filariasis immunochromatographic tes... more

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Communication in neglected Tropical Diseases' elimination: A scoping review and call for action

Nieto-Sanchez C., Hatley DM, Gijalva MJ., et al. (2022) CC

PLoS Negl Trop Dis 16(10): e0009774. Although the practice of communication is often called upon when intervening asn involgvingcommunties affected by NTD's, the disciplinary framewokr of healt communication research has been largely absent from NTD strategies. To illustrate how practices conceptual... more

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The impact of residual infections on Anopheles-transmitted Wuchereria bancrofti after multiple rounds of mass drug administration

D. K. de Souza; Ansumana, R.; Sessay, S.; et al. Parasites & Vectors (2015) CC

Many countries have made significant progress in the implementation of World Health Organization recommended preventive chemotherapy strategy, to eliminate lymphatic filariasis (LF). However, pertinent challenges such as the existence of areas of residual infections in disease endemic districts pose... more

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An open label, block randomized, community study of the safety and efficacy of coadministered ivermectin, diethylcarbamazine plus albendazole vs. diethylcarbamazine plus albendazole for lymphatic fila

JambulingamI P. , KuttiattI V.S., Krishnamoorthy K. et al (2021) C2

Better drug regimens for mass drug administration (MDA) could accelerate the Global Programme to Eliminate Lymphatic Filariasis (LF). This community study was designed to compare the safety and efficacy of MDA with IDA (ivermectin, diethylcarbamazine and albendazole) or DA (diethylcarbamazine and ... more

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Standard operating procedures for supply chain management of health products for neglected tropical diseases amenable to preventive chemotherapy
recommended

World Health Organization WHO (2022) C_WHO

Tis first edition describes the standard operating procedures for health products for NTDs amenable to preventive chemotherapy and the medicines donated to treat them. These include albendazole for lymphatic filariasis and soil-transmitted helminthiases; azithromycin for trachoma and yaws; diethylca... more

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Supply chain management of NTD health products for NTD programmes

Open WHO; World Health Organization WHO (2022) C_WHO

A key component of achieving control and elimination of neglected tropical diseases (NTDs) is effective supply chain management of preventive chemotherapy drugs for Mass Drug Administration (MDA) for trachoma, river blindness, lymphatic filariasis, soil-transmitted helminthiasis and schistosomiasis.... more

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Water sanitation and hygiene for accelerating and sustaining progress on neglected tropical diseases: A global strategy 2015-2020

World Health Organization (WHO) (2015) C_WHO

Water, sanitation and hygiene (WASH) are critical in the prevention and care for all of the 17 neglected tropical diseases (NTDs) scheduled for intensified control or elimination by 2020.
Provision of safe water, sanitation and hygiene is one of the five key interventions within the global NTD ... more

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Clinical guidelines - Diagnosis and treatment manual Chapter 6: Parasitic diseases

MSF, Dubois, G.; Vasseur-Binachon, B.; Yoshimoto, C. Médecins Sans Frontières (2022) CC

Chapter 6 contents Malaria Human African trypanosomiasis (sleeping sickness) American trypanosomiasis (Chagas disease) Leishmaniases Intestinal protozoan infections (parasitic diarrhoea) Flukes Schistosomiases Cestodes Nematode infections Filariasis ... more

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A toolkit for integrated vector management in sub-Saharan Africa

World Health Organization (WHO) (2016) C_WHO

This toolkit for integrated vector management (IVM) is designed to help national and regional programme managers coordinate across sectors to design and run large IVM programmes.
The toolkit provides the technical detail required to plan, implement, monitor and evaluate an IVM approach. IVM can... more

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Current epidemiological evidence for predisposition to high or low intensity human helminth infection: a systematic review

Wright J.E., Werkman M., Dunn J.C. et al Parasites and Vectors (2018) C2

Background: The human helminth infections include ascariasis, trichuriasis, hookworm infections, schistosomiasis, lymphatic filariasis (LF) and onchocerciasis. It is estimated that almost 2 billion people worldwide are infected with helminths. Whilst the WHO treatment guidelines for helminth infecti...ons are mostly aimed at controlling morbidity, there has been a recent shift with some countries moving towards goals of disease elimination through mass drug administration, especially for LF and onchocerciasis. However, as prevalence is driven lower, treating entire populations may no longer be the most efficient or cost-effective strategy. Instead, it may be beneficial to identify individuals or demographic groups who are persistently infected, often termed as being “predisposed” to infection, and target treatment at them. Methods: The authors searched Embase, MEDLINE, Global Health, and Web of Science for all English language, humanbased papers investigating predisposition to helminth infections published up to October 31st, 2017. The varying definitions used to describe predisposition, and the statistical tests used to determine its presence, are summarised. Evidence for predisposition is presented, stratified by helminth species, and risk factors for predisposition to infection are identified and discussed. Results: In total, 43 papers were identified, summarising results from 34 different studies in 23 countries. Consistent evidence of predisposition to infection with certain species of human helminth was identified. Children were regularly found to experience greater predisposition to Ascaris lumbricoides, Schistosoma mansoni and S. haematobium than adults. Females were found to be more predisposed to A. lumbricoides infection than were males. Household clustering of infection was identified for A. lumbricoides, T. trichiura and S. japonicum. Ascaris lumbricoides and T. trichiura also showed evidence of familial predisposition. Whilst strong evidence for predisposition to hookworm infection was identified, findings with regards to which groups were affected were considerably more varied than for other helminth species. Conclusion: This review has found consistent evidence of predisposition to heavy (and light) infection for certain human helminth species. However, further research is needed to identify reasons for the reported differences between demographic groups. Molecular epidemiological methods associated with whole genome sequencing to determine ‘who infects whom’ may shed more light on the factors generating predisposition. more

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ANNUAL REPORT NTDs 2023

World Health Organization WHO (2024) C_WHO

This report represents the WHO-supported NTDs program activities and key performances in 2023. It is categorized into three sections: The first section states on the disease targeted for eradication (Guinea worm disease); the second section is on the Preventive Chemotherapy (PC)-NTDs (Trachoma, ... more

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Boîte à outils pour une gestion vectorielle intégrée en Afrique subsaharienne

Organisation mondiale de la Santé (OMS) (2016) C_WHO

This toolkit for integrated vector management (IVM) is designed to help national and regional programme managers coordinate across sectors to design and run large IVM programmes. The toolkit provides the technical detail required to plan, implement, monitor and evaluate an IVM approach. IVM can be ... more

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Baseline Mapping of Neglected Tropical Diseases in Africa: The Accelerated WHO/AFRO Mapping Project

Rebollo M.P., Onyeze A.N., Tiendrebeogo A. et al The American Society of Tropical Medicine and Hygiene (2021) C2

ajtmh.20-1538 Volume 104, 6. Mapping is a prerequisite for effective implementation of interventions against neglected tropical diseases (NTDs). Before the accelerated World Health Organization (WHO)/Regional Office for Africa (AFRO) NTD Mapping Project was initiated in 2014, mapping efforts in man... more

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Control, interrupción de la transmisión y eliminación de la enfermedad de Chagas como problema de salud pública. Guía de evaluación, verificación y validación

Organización Panamericana de la Salud OPS (2019) C_WHO

La enfermedad de Chagas, también llamada tripanosomiasis americana, sigue siendo endémica en 21 países de América Latina. Sin embargo, como consecuencia de las migraciones, la urbanización, la intensificación del turismo, la modificación de las estrategias agrícolas y el cambio climático, l...a enfermedad ha traspasado el marco rural y el ámbito latinoamericano que le dieron identidad durante decenios, y ha logrado instalarse en la periferia de las ciudades del área endémica y en países de América del Norte, Europa, Asia y Oceanía y transformarse en un problema de salud pública global. Teniendo en cuenta que el Chagas afecta a poblaciones en situación de pobreza en las que produce graves consecuencias para la salud y la economía de las personas infectadas, y que los recursos orientados a fomentar el desarrollo de proyectos de investigación, estrategias de control y planes de atención médica a los pacientes detectados son escasos, la Organización Mundial de la Salud (OMS) incorporó esta enfermedad al grupo de enfermedades infecciosas desatendidas (EID) en el año 2005. Se reconoce actualmente la naturaleza multidimensional de la enfermedad de Chagas, cuya caracterización contempla una intrincada trama de aspectos socioculturales, políticos, biológicos, ambientales y sanitarios. Parte sustancial de todo ello radica en el carácter zoonótico de la endemia y la consiguiente imposibilidad de su erradicación. Por ende, resulta muy complicada la construcción de la ruta crítica para enfrentar esta enfermedad, con la aspiración o el objetivo de su eliminación como problema de salud pública. El propósito de esta guía es ofrecer a los Estados Miembros un instrumento que permita actualizar y estandarizar los procesos de evaluación del control, verificación de la interrupción de la transmisión, y validación de la eliminación de la enfermedad de Chagas como problema de salud pública, en consonancia con: a) la Estrategia y plan de acción para la prevención, el control y la atención de la enfermedad de Chagas; b) el Plan de acción para la eliminación de las enfermedades infecciosas desatendidas y las medidas posteriores a la eliminación 2016-2022; c) el Plan de acción sobre entomología y control de vectores 2018-2023; d) guías o procedimientos operativos estandarizados existentes para la verificación o validación de la eliminación de otras enfermedades infecciosas desatendidas (EID) como la oncocercosis, la filariasis linfática y el tracoma, y e) Enfermedades tropicales desatendidas. Prevención, control, eliminación, erradicación. more

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داء الفيلاريات اللمفي‬‬ - حقائق رئيسية

World Health Organization WHO (2022) C_WHO

يُعد داء الفيلاريات اللمفي المعروف بداء الفيل أحد أمراض المناطق المدارية المُهمَلة. وتحدث العدوى بهذا المرض عندما تنتقل الطفيليات الفيلارية إلى الإنسان عن طريق ال�... more

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Лимфатический филяриоз - Основные факты

World Health Organization WHO (2022) C_WHO

Лимфатический филяриоз, известный как слоновость, относится к числу забытых тропических болезней. Инвазия происходит в результате передачи паразитов человеку пр�... more

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Filariose lymphatique - Principaux faits

World Health Organization WHO (2022) C_WHO

La filariose lymphatique, communément appelée éléphantiasis, est une maladie tropicale négligée. L’infection se produit lorsque les parasites filaires responsables de la maladie sont transmis à l’homme par des moustiques. Généralement contractée dans l’enfance, cette infection provoq... more

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Formation sur le suivi et l’évaluation épidémiologique du traitement médicamenteux de masse pour l’élimination de la filariose lymphatique : guide des apprenants

World Health Organization WHO; Institutional research information sharing iris (2013) C_WHO

Formation sur le suivi et l’évaluation épidémiologique du traitement médicamenteux de masse pour l’élimination de la filariose lymphatique : guide des apprenants. Organisation mondiale de la Santé.

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OMS – Programme mondiale puor l´élimination de la Filaroise Lymphatique – Formation sur le suivi et l’évaluation épidémiologique du traitement médicamenteux de masse pour l’élimination de la filariose

World Health Organization WHO (2015) C_WHO

Un suivi et une évaluation efficaces sont nécessaires pour atteindre l’objectif d’élimination de la filariose lymphatique (FL). Après le traitement médicamenteux de masse (TMM) conformément aux lignes directrices élaborées par l’OMS, des programmes doivent être mis en œuvre afin de d... more

Operational manual on indoor residual spraying: Control of vectors of malaria, Aedes-borne diseases, Chagas disease, leishmaniases and lymphatic filariasis recommended

Bench Aids for the diagnosis of filarial infections recommended

Standard operating procedures for supply chain management of health products for neglected tropical diseases amenable to preventive chemotherapy recommended

Operational manual on indoor residual spraying: Control of vectors of malaria, Aedes-borne diseases, Chagas disease, leishmaniases and lymphatic filariasis
recommended

Bench Aids for the diagnosis of filarial infections
recommended

Standard operating procedures for supply chain management of health products for neglected tropical diseases amenable to preventive chemotherapy
recommended