By almost any measure, human health is better now than at any time in history. Life expectancy has soared from 47 years in 1950–1955, to 69 years in 2005–2010, and death rates in children younger than 5 years of age have decreased substantially, from 214 per thousand live births in 1950–1955, ...to 59 in 2005–2010. But these gains in human health have come at a high price: the degradation of nature’s ecological systems on a scale never seen in human history. A growing body of evidence shows that the health of humanity is intrinsically linked to the health of the environment, but by its actions humanity now threatens to destabilise the Earth’s key life-support systems.
As a Commission, we conclude that the continuing degradation of natural systems threatens to reverse the health gains seen over the last century. In short, we have mortgaged the health of future generations to realise economic and development gains in the present.
Despite present limitations, the Sustainable Development Goals provide a great opportunity to integrate health and sustainability through the judicious selection of relevant indicators relevant to human wellbeing, the enabling infrastructure for development, and the supporting natural systems, together with the need for strong governance.
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Nat Commun 9, 5370 (2018). https://doi.org/10.1038/s41467-018-07804-8. Mycobacterium ulcerans is the causative agent of Buruli ulcer, a neglected tropical skin disease that is most commonly found in children from West and Central Africa. Despite the severity of the infection, therapeutic options are... limited to antibiotics with severe side effects. Here, we show that M. ulcerans is susceptible to the anti-tubercular drug Q203 and related compounds targeting the respiratory cytochrome bc1:aa3. While the cytochrome bc1:aa3 is the primary terminal oxidase in Mycobacterium tuberculosis, the presence of an alternate bd-type terminal oxidase limits the bactericidal and sterilizing potency of Q203 against this bacterium. M. ulcerans strains found in Buruli ulcer patients from Africa and Australia lost all alternate terminal electron acceptors and rely exclusively on the cytochrome bc1:aa3 to respire. As a result, Q203 is bactericidal at low dose against M. ulcerans replicating in vitro and in mice, making the drug a promising candidate for Buruli ulcer treatment.
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Background: Atherosclerotic cardiovascular diseases (ASCVD) including myocardial infarction, stroke and peripheral arterial disease continue to be major causes of premature death, disability and healthcare expenditure globally. Preventing the accumulation of cholesterol-containing atherogenic lipopr...oteins in the vessel wall is central to any healthcare strategy to prevent ASCVD. Advances in current concepts about reducing cumulative exposure to apolipoprotein B (apo B) cholesterol-containing lipoproteins and the emergence of novel therapies provide new opportunities to better prevent ASCVD. The present update of the World Heart Federation Cholesterol Roadmap provides a conceptual framework for the development of national policies and health systems approaches, so that potential roadblocks to cholesterol management and thus ASCVD prevention can be overcome.
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Vous avez appris, il y a peu de temps ou peut-être plus, que vous étiez séropositif·ve.
Peut-être vous attendiez-vous un peu à ce résultat, peut-être pas du tout. Vous avez peut-être ressenti un
choc à cette annonce, et une foule de questions vous sont venues.
Cette brochure a pour bu...t de répondre à certaines d’entre elles et, en abordant différents aspects, de vous
aider petit à petit à apprivoiser votre nouvelle situation.
Les avancées médicales ont été extrêmement importantes ces dernières années, tant au niveau des traitements qu’au niveau des stratégies de prévention. Avec des conséquences concrètes. Les personnes vivant
avec le VIH sont aujourd’hui considérées comme des patient·es atteint·es d’une maladie chronique, avec laquelle on peut vivre de très nombreuses années, pour autant que l’on prenne correctement son traitement.
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Directives de soins pour les centres de transfert de premier niveau dans les pays en développement
Autres troubles
Chapitre H.2
Edition en français Traduction : Vladimir Ferrafiat Sous la direction de : Priscille Gérardin Avec le soutien de la SFPEADA
L’Assemblée Nationale a délibéré et adopté en sa séance du 23 janvier 2015 la loi dont la teneur suit: PREMIERE PARTIE DES DISPOSITIONS GENERALES
Recommendations for health care professionals – the experience from Latvia
Climate Change 2021: The Physical Science Basis. Contribution of Working Group I to the Sixth Assessment Report of the Intergovernmental Panel on Climate Change
This document presents a policy to guide and support Member States of the Pan American Health Organization (PAHO) and the Pan American Sanitary Bureau (PASB) in their technical cooperation to improve mental health as a priority for advancing health, social, and economic development in the Region in ...the context of the COVID-19 pandemic and beyond.
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Introduction
Chapitre A.2
Edition en français
Traduction : Lisa Vitte, Anne-Sophie Perrin
Sous la direction de : Priscille Gérardin Avec le soutien de la SFPEADA
Вариативные рекомендации 24 сентября 2021 г.
Этот документ представляет собой текущие рекомендации ВОЗ. В них будут вноситься изменения и дополнения,
касающиеся нов...ых средств для лечения COVID-19, в том числе гидроксихлорохина и комбинации лопинавира и
ритонавира . Размещение, распространение и обновление данных рекомендаций происходит в приложении
MAGICapp, а их формат и структура обеспечивают для пользователей удобство работы и поиска. Реализована
функция постоянного обновления информации, относящейся к действующим положениям, которая позволяет
знакомиться с новыми данными наряду с актуальными рекомендациями. В разделе 4 описаны основные
методологические аспекты процедуры составления вариативных рекомендаций.
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Lettre Encyclique Laudato Si' du Saint-Père Francois sur la sauvegarde de la maison commune
The article focuses on "The State of the World’s Children 2023" report published by UNICEF. It highlights the critical role of vaccines in saving lives and the challenges in global immunization efforts, especially for marginalized and underserved children. The report emphasizes the impact of COVID...-19 on routine immunization, leaving millions of children unprotected from preventable diseases. It calls for urgent measures to restore and improve vaccination coverage, ensure equity in vaccine access, strengthen primary healthcare systems, and build trust in vaccines. The report also advocates for innovations and sustainable funding to achieve immunization for every child.
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Les premiers secours psychologiques sont un moyen simple, mais efficace, d'aider une personne en détresse. Ils consistent à prêter attention aux réactions de la personne, à l'écouter activement et, le cas échéant, à lui apporter une aide pratique pour l'aider à résoudre ses problèmes imm...édiats et à satisfaire ses besoins fondamentaux. L'apprentissage des premiers secours psychologiques et la compréhension des réactions aux crises permettent aux personnes qui les pratiquent d'aider les autres et d'appliquer ces mêmes compétences à leur propre vie.
A Short Introduction to Psychological First Aid contains chapters about What is PFA, Who needs PFA and How to provide PFA. It also contains a short introduction to PFA for children and PFA in Groups.
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