Lancet Glob Health 2016; 4: e856–63. Open Access
The article "Effectiveness of one dose of oral cholera vaccine in response to an outbreak: a case-cohort study" investigates whether a single dose of the Shanchol oral cholera vaccine can provide effective protection during an outbreak. Conducted i...n Juba, South Sudan, in 2015, the study involved a case-cohort approach, analyzing vaccination status and disease outcomes.
Findings showed that a single dose was 80.2% effective in preventing medically attended cholera cases, increasing to 87.3% after adjustments for confounding factors. These results suggest that a single-dose strategy can be an effective emergency response, particularly in settings with limited vaccine supply and high mobility of affected populations. The study supports using a single-dose approach during outbreaks when a two-dose regimen is logistically challenging.
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Towards Universal Access to Prevention, Diagnosis and Treatment
Millions of children in Yemen could be pushed to ‘the brink of starvation’ due to huge shortfalls in humanitarian aid funding amid the COVID-19 pandemic – according to a new UNICEF report marking more than five years since conflict escalated in the country.
Le document fournit des directives complètes pour la gestion des flambées de choléra, y compris la détection, la confirmation, la réponse, le traitement et la prévention. Il met l'accent sur l'importance de la réhydratation, de l'assainissement de l'eau, de la promotion de l'hygiène et de la... mobilisation communautaire pour limiter la propagation. Ce guide est conçu pour les professionnels de la santé et les autorités publiques afin d'assurer une réponse efficace et coordonnée.
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