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Syria: 2016 Humanitarian Response Plan Monitoring Report, January-June 2016

UN Office for the Coordination of Humanitarian Affairs (2016) C1

Now entering its sixth year, the conflict in Syria continues to take a drastic toll on the lives of the Syrian people and to drive an unprecedented humanitarian and protection crisis: some 13.5 million people are now in need of humanitarian assistance and protection, including 6 million children. Ha... more

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Current epidemiological evidence for predisposition to high or low intensity human helminth infection: a systematic review

Wright J.E., Werkman M., Dunn J.C. et al Parasites and Vectors (2018) C2

Background: The human helminth infections include ascariasis, trichuriasis, hookworm infections, schistosomiasis, lymphatic filariasis (LF) and onchocerciasis. It is estimated that almost 2 billion people worldwide are infected with helminths. Whilst the WHO treatment guidelines for helminth infecti...ons are mostly aimed at controlling morbidity, there has been a recent shift with some countries moving towards goals of disease elimination through mass drug administration, especially for LF and onchocerciasis. However, as prevalence is driven lower, treating entire populations may no longer be the most efficient or cost-effective strategy. Instead, it may be beneficial to identify individuals or demographic groups who are persistently infected, often termed as being “predisposed” to infection, and target treatment at them. Methods: The authors searched Embase, MEDLINE, Global Health, and Web of Science for all English language, humanbased papers investigating predisposition to helminth infections published up to October 31st, 2017. The varying definitions used to describe predisposition, and the statistical tests used to determine its presence, are summarised. Evidence for predisposition is presented, stratified by helminth species, and risk factors for predisposition to infection are identified and discussed. Results: In total, 43 papers were identified, summarising results from 34 different studies in 23 countries. Consistent evidence of predisposition to infection with certain species of human helminth was identified. Children were regularly found to experience greater predisposition to Ascaris lumbricoides, Schistosoma mansoni and S. haematobium than adults. Females were found to be more predisposed to A. lumbricoides infection than were males. Household clustering of infection was identified for A. lumbricoides, T. trichiura and S. japonicum. Ascaris lumbricoides and T. trichiura also showed evidence of familial predisposition. Whilst strong evidence for predisposition to hookworm infection was identified, findings with regards to which groups were affected were considerably more varied than for other helminth species. Conclusion: This review has found consistent evidence of predisposition to heavy (and light) infection for certain human helminth species. However, further research is needed to identify reasons for the reported differences between demographic groups. Molecular epidemiological methods associated with whole genome sequencing to determine ‘who infects whom’ may shed more light on the factors generating predisposition. more

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Chagas Disease: From Discovery to a Worldwide Health Problem Infectious Diseases

Freitas Lidani, K.; Antunes Andrade, F.; Bavia, L.; et. al. Frontiers Public Health (2019) CC

Front. Public Health, 02 July 2019 Sec. Infectious Diseases: Epidemiology and Prevention Volume 7 - 2019 | https://doi.org/10.3389/fpubh.2019.00166 Chagas disease (CD) is an anthropozoonosis caused by the protozoan parasite Trypanosoma cruzi, that affects about 6–8 million people worldwide (1) a... more

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Modelling the climatic suitability of Chagas disease vectors on a global scale

Ebehard, F.; Cunze, S.; Kochmann, J., Klimpel, S. eLife Sciences Publications (2020) CC

eLife 2020;9:e52072. The Triatominae are vectors for Trypanosoma cruzi, the aetiological agent of the neglected tropical Chagas disease. Their distribution stretches across Latin America, with some species occurring outside of the Americas. In particular, the cosmopolitan vector, Triatoma rubrofasci... more

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WHO implementation tool for pre-exposure prophylaxis of HIV infection - Module 11

World Health Organization (WHO) World Health Organization (WHO) (2017) C_WHO

Module 1q PrEP users July 2017 Module 11: PrEP users. This module provides information for people who are interested in taking PrEP to reduce their risk of acquiring HIV and people who are already taking PrEP – to support them in their choice and use of PrEP. This module gives ideas for cou... more

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Covid Vaccine Facts with the WHO's Dr. Kate O'Brien (video)

Healthcare Triage (2021) CC

YouTube influencer Healthcare Triage talked with WHO's Dr Kate O'Brien about how the COVID-19 vaccine works, how it gets distributed, and how we distribute it equitably. 1:27 Safety questions and concerns about quick development of the vaccine. 7:18 Have we entered a new age where all vaccines wi... more

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Solidarity” clinical trial for COVID-19 treatments

World Health Organization WHO (2020) CC

Solidarity” is an international clinical trial to help find an effective treatment for COVID-19, launched by the World Health Organization and partners. The Solidarity Trial will compare four treatment options against standard of care, to assess their relative effectiveness against COVID-19. By... more

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An economic investment case & financing requirements

ACT-Accelerator: An economic investment case & financing requirements (2021) C_WHO

This document lays out economic arguments for investing in the Access to COVID-19 Tools Accelerator (ACT-Accelerator). Framed within an overall context that recognizes the broader human health and societal impacts of the COVID-19 crisis, ACT-Accelerator's Economic Investment Case argues that investm... more

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Business Guide: North-East Nigeria, South Sudan, Yemen and Somalia: Prevent Famine and Support Response

UN Office for the Coordination of Humanitarian Affairs (2017)

More than 20 million people in North-East Nigeria, South Sudan, Yemen and Somalia are facing famine or a credible risk of famine over the coming six months. Some 1.4 million children are currently at imminent risk of death from malnutrition. To avert a major humanitarian catastrophe the United Nat... more

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COVID-19 Vaccine Development and Access Strategy

African Union; Africa CDC Centres for Disease Control and Prevention (2020) C1

Available in English, French, Portuguese and Arabic Successful immunization of a critical mass of the African population with one or several safe and efficacious COVID-19 vaccines.Key objectives1. Accelerate African involvement in the clinical development of a vaccine. 2. Ensur... more

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Global health 2035: a world converging within a generation

Jamison D.; Summers L.; Alleyne G. et al. (2014) C1

Prompted by the 20th anniversary of the 1993 World Development Report, a Lancet Commission revisited the case for investment in health and developed a new investment frame work to achieve dramatic health gains by 2035. Our report has four key messages, each accompanied by opportunities for action... more

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Fact Sheet Hypertension

World Health Organization (WHO) World Health Organization (WHO) (2023) C_WHO

The World Health Organization's fact sheet on hypertension provides a comprehensive overview of high blood pressure, highlighting its prevalence, risk factors, and health implications. It emphasizes that hypertension is a major cause of premature death worldwide, with an estimated 1.28 billion adult... more

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Towards a malaria-free world: elimination of malaria in Uzbekistan

World Health Organization WHO (2024) C_WHO

This publication describes the history of malaria in Uzbekistan. It evaluates the policies and strategies applied after the re-establishment of local transmission to contain malaria outbreaks in the 1990s and early 2000s, and highlights the interventions subsequently used to eliminate malaria in the... more

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WHO recommends HIV self-testing – evidence update and considerations for success

World Health Organization WHO (2019) C_WHO

Policy brief. HIV self-testing (HIVST) is a convenient and confidential option for HIV testing. In 2016 WHO recommended HIVST as a safe, accurate and effective way to reach people who may not test otherwise, including people from key populations, men and young people. Lay users can perform HIVST r... more

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Climate change and health: vulnerability and adaptation assessment

World Health Organisation (WHO) (2021) C_WHO

Climate change and health vulnerability and adaptation assessment In 2013 the World Health Organization (WHO) published the report Protecting health from climate change: vulnerability and adaptation assessment. The aim was to provide basic and flexible guidance on conducting national or subnati... more

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Guide for the management of people on the move living with HIV in reception centers during the COVID-19 emergency

UNAIDS (2020) C_WHO

The COVID-19 pandemic has had an unprecedented impact on health care systems that, in many instances, worsened the already existing assistance gaps. When it comes to Latin America and Central America, this challenge adds to the consequences mass mobilizations have had in recent years, which have exc... more

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"Community Health" Community of Practice (CH CoP)

Collectivity (2021) CC

The Community Health Community of Practice (CH CoP) builds on the Institutionalisation Community Health Conference co-hosted by USAID and UNICEF in Johannesburg in March 2017. Conceived as an ‘open space’ in terms of both contribution and access to knowledge, it aims at gathering practitioners, ... more

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Manual for the Public Health Management of Chemical Incidents (English, French and Spanish version)

World Health Organization (2009) C_WHO

The purpose of the WHO Manual for the Public Health Management of Chemical Incidents is to provide a comprehensive overview of the principles and roles of public health in the management of chemical incidents and emergencies. While this information is provided for each phase of the emergency cycle, ... more

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Guidance on easing lockdown

Africa CDC Centers for Disease Control and Prevention (2020) CC

In response to the first cases of coronavirus disease 2019 (COVID-19) reported on the continent, many African Union Member States implemented large-scale public health and social measures (PHSM) rapidly. These measures were aimed at reducing transmission and the number of new cases being reported, p... more

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Prevention and control of antimicrobial resistance in the Eastern Mediterranean Region – a progress report, 2024

World Health Organization WHO (2024) C_WHO

Antimicrobial resistance (AMR) is a global public health crisis that resulted in 1.14 million deaths in 2021. According to the Institute for Health Metrics and Evaluation estimates, 96 416 of these deaths occurred in the World Health Organization (WHO) Eastern Mediterranean Region. All 22 countr... more