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As countries presented their epidemiological and programmatic situations, and WHO summarized the global status of HAT, the central message was one of satisfaction with the remarkable progress towards elimination. A historically low number of cases was reported, despite maintaining high levels of act ... more
In this subsequent part of the issue brief on the NTD Toolbox you will learn about general strategies, roadmaps, key treatment guidelines, reports, and training material on Dengue & Chikungunya, Human African Trypanosomiasis and Leprosy.
Key facts
Fact Sheet
Fact Sheet
Resource Platform
Learning sheet no. 4 Accessed March, 2025
DPDx Laboratory Identification of Parasites of Public Health Concerns Including Life cycle
Chapter in Clinical guidelines -Diagnosis and Treatment manual
Accessed March, 2025
The Global Health Observatory
The Global Health Observatory
The Lancet Infectious Disease Volume 25, Issue 2e77-e85February 2025
Human African trypanosomiasis (HAT), or sleeping sickness, is caused by trypanosome parasites that are transmitted by tsetse flies. HAT is found only in sub-Saharan Africa. Two subspecies of Trypanosoma brucei cause disease: T. b. gambiense in West and Central Africa, and T. b. rhodesiense in East A ... more
The present guidelines incorporate all these changes, leading to a substantial reconfiguration of therapeutic choices for both disease forms. HAT is a serious, life-threatening disease and the efficacy of fexinidazole depends on swallowing the medicine after an appropriate intake of food as well as ... more
PLOS Neglected Tropical Diseases 18(5): e0012091. https://doi.org/10.1371/journal.pntd.0012091
PLOS Neglected Tropical Diseases 18(4): e0012111. https://doi.org/10.1371/journal.pntd.0012111
Guidelines for the treatment of human African trypanosomiasis. Web Annex A. Commissioned by WHO Cochrane Response
WHO Guidelines for the Treatment of Human African Trypanosomiasis. Web Annex B