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1
Guidelines for the Prevention and Treatment of Opportunistic Infections in Children With and Exposed to HIV
recommended
Full Guidelines
Dosing Recommendations for Prevention and Treatment
Archives of Medicine vo.7 no.5:10
Individuals infected with human immunodeficiency virus (HIV) often develop
multiple complications and comorbidities, among them, opportunistic infections.
The highest incidence of opportunistic infections was reported in the group
of patients with CD4 lymphocyte
...
levels below 200 cells / mm. Candidiasis,
toxoplasmosis and pneumocystis pneumonia (PCP) were the main representatives.
more
These 2025 guidelines respond to the need for better approaches to identify advanced HIV disease, improve the poor outcomes of people living with HIV being discharged from hospital and provide updated guidance for treatment for Kaposi’s sarcoma through evidence-informed recommendations. The public
...
ation contains recommendations that are from previously published WHO guidelines documents on advanced HIV disease and introduces new recommendations that were developed in 2025.
more
Core Guidance. Differentiated service delivery is highlighted as a key approach for HIV programmes to enhance implementation quality and efficiency.
This is the 2025 draft Malawi Guidelines for Syndromic Management of Sexually Transmitted Infections which is yet to be approved by the SMT.
Technical Document
A Training Curriculum
a comprehensive guide
for the HCPs who work in counselling and psychological care of children and adoles-
cents. The Handbook includes information on HIV clinical care; growth and development;
mental health; child protection; counselling and communication; disclosure; loss, grief,
and bereavemen
...
t; adherence; sexual and reproductive health; transition of care; support
systems; and monitoring and evaluation of psychosocial services. The material provided
in the Handbook aims to equip HCPs with important information that will help them to
maximise resiliency, minimise risk factors, and promote positive personal growth among
the children and adolescents they care for who are living with or affected by HIV.
more
A Training Manual for Community Service Providers
A Clinical Guideline for the Diagnosis and Treatment of Drug-susceptible TB in Children and Adolescents
in South Africa. This new guidance is aligned with the updated WHO guidelines but has been adapted specifically for the South African context.
The intention of this publication is to provide g
...
uidance on the Diagnosis and treatment of TB in children and adolescents and they may be downloaded and distributed as required. Distribution for remuneration is not permitted. No changes to the content or format of this publication is permitted.
more
This document aims to provide Ministry of Health guidance on the implementation of PEP and PrEP to prevent HIV transmission and improve overall health outcomes. This comprehensive approach reflects the commitment of all involved in combating HIV and enhancing public health.
The guide presents a structured framework covering assessment and planning, service delivery models, integration with broader health and social services, monitoring, and sustainability. It emphasizes community leadership, human rights, equitable access and adaptation to local contexts, including clo
...
sed settings. Practical tools are included to support implementation and accelerate progress towards global targets for controlling HIV and eliminating viral hepatitis epidemics.
more
The WHO publication “Surveillance, case investigation and contact tracing for mpox: interim guidance” provides updated global technical guidance on monitoring and responding to mpox (formerly known as monkeypox). It explains how countries should conduct surveillance to detect new outbreaks, car
...
ry out case investigation including clinical assessment and lab specimen collection, and perform contact tracing to monitor people exposed to confirmed or probable cases in order to stop transmission and protect at-risk groups. The guidance includes practical recommendations for how long contacts should be monitored (e.g., daily for 21 days without requiring quarantine if symptom-free) and advising good hygiene and reduced exposure risk during the monitoring period. This interim guidance is intended to support public health authorities worldwide in strengthening mpox outbreak detection, response, and reporting.
more
The document “Mpox Continental Response Plan 2.0” outlines the strategy developed by the Africa Centres for Disease Control and Prevention (Africa CDC) in collaboration with the World Health Organization (WHO) to respond to the ongoing mpox outbreak across Africa. The plan describes coordinated
...
actions to strengthen surveillance, laboratory capacity, case detection and contact tracing in affected countries. It also focuses on improving access to vaccines, diagnostics and treatment, supporting healthcare systems, and enhancing risk communication and community engagement. In addition, the document highlights the importance of regional and international cooperation, resource mobilization and technical support to help African countries control the outbreak and prevent further spread. Overall, the plan serves as a continental framework to guide a coordinated public health response to mpox in Africa.
more
Southern African Journal of HIV Medicine
A Guide for Community Case Workers in OVC Programs. This guide is meant to help you, a community case worker or
facility case manager working on an orphans and vulnerable children (OVC) program, to understand your role in supporting
multi-month dispensing (MMD) of anti-retroviral (ARV) medicines f
...
or children and adolescents living with HIV (CLHIV/ALHIV).
more
International Journal for Parasitology: Drugs and Drug Resistance Volume 28, August 2025, 100602
This review provides innovative insights to circumvent antimalarial drug resistance and diversify malaria therapeutics.
Preparedness and response to bacterial meningitis outbreaks: toolkit for frontline healthcare workers
recommended
Designed as a suite of job aids on acute bacterial meningitis, this document serves as a resource for frontline healthcare professionals globally, including in settings where the risk of outbreaks and excess mortality is highest. With a primary focus on acute bacterial meningitis in children aged ov
...
er 1 month, adolescents and adults, the toolkit provides clinical guidance on the causative pathogens, clinical manifestations, diagnostic investigations, antibiotic therapy, adjunctive treatment, supportive care, post-exposure antibiotic prophylaxis, and infection prevention and control in healthcare settings.
more
