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Pathogens . 2021 Nov 16;10(11):1493.doi: 10.3390/pathogens10111493
.Chronic manifestations of Chagas disease present as disabling and life-threatening condi-tions affecting mainly the cardiovascular and
...
gastrointestinal systems. Although meaningful research has outlined the different molecular mechanisms underlying Trypanosoma cruzi’s infection and the host-parasite interactions that follow, prompt diagnosis and treatment remain a challenge, particu-larly in developing countries and also in those where the disease is considered non-endemic. This review intends to present an up-to-date review of the parasite’s life cycle, genetic diversity, virulence factors, and infective mechanisms, as well as the epidemiology, clinical presentation, diagnosis, and treatment options of the main chronic complications of Chagas disease.
more
The WHO health advisory provides guidance to countries on adapting all existing preparedness and response plans and procedures for natural hazards such as cyclones, tropical storms, tornadoes, flood
...
s, earthquakes and potential outbreaks of other diseases to their existing COVID-19 strategic preparedness and response plans. It advises countries to sustain all established public health and social measures to prevent and control COVID-19 while simultaneously preparing for responding to and effectively manage other disaster risks and events. It highlights WHO’s call for local, national, regional and global solidarity to support countries and communities with high levels of vulnerability to natural hazards during the COVID-19 pandemic.
more
Women, girls and marginalized groups who are largely dependent on natural resources for livelihoods are among the hardest hit by extreme weather patterns. These weather patterns limit their access to food, water, shelter, education
...
and access to essential health services, including those that address sexual and reproductive health and rights (SRHR), gender-based violence (GBV) and preventing harmful practices such as child marriage and female genital mutilation.
more
Toolkit regarding Zika Virus
Development assistance for health (DAH)
plays a vital role in supporting health programmes in lowand middle-income countries. While DAH has historically
focused on infectious diseases and maternal and
...
child
health, there is a lack of comprehensive analysis of DAH
trends, strategic shifts and their impact on health systems
and outcomes. This study aims to provide a comprehensive
review of DAH from 1990 to 2022, examining its evolution
and funding allocation shifts.
more
This issue brief provides information about TB and HIV clinical trials and research programs
impacted by U.S. government funding disruptions, and
...
proposes urgent actions that
donor agencies, governments, and philanthropies can take to preserve scientific advances
underway and prevent the collapse of TB and HIV medical research in South Africa
more
Biennial Report. SUBMITTED TO THE UNITED NATIONS GENERAL ASSEMBLY SPECIAL SESSION ON HIV AND AIDS
Reporting period: January 2012 – December 2013
Young People and Alcohol. A resource book
Yvonne Bonomo, Cornelius Goos, John Howard et al.
World Health Organization, Western Pacific Region
(2015)
C_WHO
The paper sets out the specific communication challenge posed by Ebola and why it was so difficult to get to grips with this in the early months of the outbreak. It thendocuments when the health communication response became more useful
...
and explores what that tells us about effective media and communication. Finally, it offers recommendations to ensure that media and communication are used to their full potential during other disease outbreaks and humanitarian crisis
more
UGANDA NATIONAL TUBERCULOSIS AND LEPROSY CONTROL PROGRAMME