The document outlines essential steps and provides guidance to countries on the adoption and deployment of c-IPTp so that it is integrated into the existing health system. It draws upon best practices and lessons learned from pilot implementation experiences in eight African countries and targets st...akeholders at the national level that are involved in the provision of maternal and child services, including national and local policymakers and implementers of malaria, maternal health, child health, reproductive health and community health programmes, and nongovernmental and other organizations.
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El año 2024 fue especialmente difícil para la infancia. Los conflictos cada vez más violentos, las conmociones climáticas y la pobreza provocaron un aumento drástico de las necesidades de los niños y niñas, justo cuando los recursos necesarios para atenderlas se reducían de forma constante. ...
Pese a todo, tal como muestra este Informe anual, UNICEF mantuvo su presencia en más de 190 países y territorios, donde protegió y salvó la vida a millones de niños y niñas incluso en los lugares más remotos. En colaboración con nuestros aliados, suministramos agua salubre e instalaciones de saneamiento, brindamos protección y apoyo psicosocial y prestamos servicios de salud, nutrición, inmunización, educación y capacitación.
En 2025, el panorama mundial sigue estando presidido por cambios políticos importantes, volatilidad, incertidumbre económica y crisis humanitarias cada vez más graves. Si queremos rendir frutos, UNICEF debe dar lo mejor de sí.
Pero los recortes en la financiación –los que ya se han anunciado y los que hay previstos– están limitando la capacidad de UNICEF para llegar a millones de niños y niñas en situación de extrema necesidad. Estos nuevos recortes están generando una crisis mundial de financiación que pondrá en peligro la vida de millones de niños y niñas más.
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Mozambique was the first country outside of the Sahel to successfully implement seasonal malaria chemoprevention (SMC) on a large scale. This learning paper captures some of the lessons drawn from the implementation process.
The article introduces Pf-HaploAtlas, a new online tool developed by MalariaGEN to track genetic mutations in the Plasmodium falciparum parasite—the most deadly malaria-causing species. This app allows researchers and public health professionals to explore global data on drug resistance mutations ...and genetic variation across thousands of parasite genomes. The tool is designed to improve understanding of how malaria parasites evolve and spread, and to support efforts in monitoring antimalarial drug resistance. With an intuitive interface, Pf-HaploAtlas enables users to visualize haplotype patterns, compare regional differences, and access up-to-date data that can inform control strategies and research.
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The WHO Malaria Threats Map is an interactive online platform that showcases the latest global data on four critical biological threats to effective malaria control and elimination: mosquito insecticide resistance, Plasmodium falciparum hrp2/3 gene deletions, antimalarial drug resistance, and the ...spread of invasive vector species. Designed for public health professionals and researchers, the map allows users to explore and filter data regionally, track emerging resistance patterns, and view visual trends. Its purpose is to inform strategies for surveillance, guide policy-making, and support efforts to eliminate malaria, particularly by anticipating and responding to biological challenges that could undermine control programs.
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Malaria ist nach wie vor eine lebensbedrohliche Krankheit, insbesondere in Afrika. Jährlich gibt es rund 228 Millionen Fälle mit hohen Sterberaten, vor allem bei Kindern unter fünf Jahren. Drei Absolvent:innen des Masterstudiengangs „Applied Information and Data Science“ entwickeln die Smartp...hone-App „Malatec“, die eine schnelle und kostengünstige Malaria-Diagnose ermöglichen soll. Die Diagnose erfolgt mithilfe eines preiswerten, 3D-gedruckten Mikroskops (unter 5 CHF) in Kombination mit einem Algorithmus, der auf neuronalen Netzen basiert und die Malaria-Parasiten in gefärbten Blutproben automatisch erkennt und zählt.
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The WorldWide Antimalarial Resistance Network (WWARN) is a global collaborative platform that provides the malaria community with innovative tools and reliable evidence to help them understand and address antimalarial drug resistance. Using molecular surveyors and mapping tools, WWARN visualises the... evolution and geographical spread of resistance to key antimalarial drugs.
Accessed June 2025
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Medicine 2024;103:29(e39010. This review underscores the urgency of adapting to the changing landscape of malaria transmission driven by climate change. It emphasizes the significance of proactively addressing climate-related challenges to enhance malaria control and protect the health and well-bein...g of vulnerable populations.
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Malaria Journal (2024) 23:255. Seasonal malaria chemoprevention (SMC) is a World Health Organization-recommended intervention for the prevention of malaria among children at high risk in areas with seasonal transmission. During the coronavirus disease 2019 (COVID-19) pandemic, SMC drug distribution ...was rapidly adapted to reduce contact and mitigate the risk of transmission between communities and community distributors, with caregivers administering doses.
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Malaria No More is a non-profit organisation dedicated to eradicating malaria, a preventable and treatable disease, in our lifetime. Through innovative partnerships, advocacy and data-driven solutions, Malaria No More works globally to ensure access to prevention tools, diagnostics and treatment, pa...rticularly in vulnerable regions. Malaria No More focuses on high-impact campaigns, technological innovation and policy engagement, collaborating with governments, health organisations and private sector partners to accelerate progress towards malaria eradication and save lives.
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The National Strategic Plan on Malaria Prevention and Elimination Period 2021 – 2025 seeks to build on the previous national successes of the National Institute of Malariology, Parasitology, and Entomology (NIMPE) while addressing current challenges to reduce the overall burden of malaria in the S...outhern and Central provinces and to initiate elimination activities in remaining focal areas of transmission throughout the country. The overall targets proposed to be reached by 2025 are:
Reduce malaria morbidity rate to below 0.015/1,000 population
Reduce malaria mortality rate to below 0.002/100,000 population
Eliminate malaria in 55 provinces
Ensure no malaria outbreaks
To address the urgent threat of drug resistance, Viet Nam has committed to accelerate efforts to eliminate locally-acquired P. falciparum by 2023.
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Integrated Outbreak Analytics (IOA) applies a multidisciplinary approach to understanding outbreak dynamics and to inform outbreak response. It aims to drive comprehensive, accountable, and effective public health and clinical strategies by enabling communities, and national and subnational health a...uthorities to use data for operational decision-making. IOA embraces a holistic perspective of outbreak dynamics throughout: from the trigger questions to the data that are collected or accessed, to the interpretation of results and the recommendations that follow. In addition, IOA promotes co-development and monitoring of evidence informed actions.
The IOA toolkit aims to provide a clear understanding of IOA and highlight the importance of using an integrated, holistic approach to manage outbreak responses. It provides step-by-step guidance for setting up IOA and putting IOA principles into action. Finally, this toolkit provides guidance on applying IOA in humanitarian and emergency contexts, offering a practical and adaptable approach to informing public health emergency responses.
Developed based on the model from the Democratic Republic of the Congo (DRC), its creation involved extensive consultation with experts experienced in IOA applications. The toolkit was piloted in Tanganyika Province, DRC, as well as Somalia and Sudan, demonstrating its adaptability to diverse emergency scenarios. It builds upon an existing array of tools, templates, reports, case studies, animations, and publications used by stakeholders in diverse contexts.
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It takes just 5 moments to change the world. Clean your hands, stop the spread of drug-resistant germs!
More than a quarter of the global population still cook meals over open fires and/or on simple stoves fuelled by firewood, agricultural waste, dried dung, charcoal, and coal. This practice results in the emission of harmful and dangerously high levels of household air pollution.
Exposure to this h...ousehold air pollution has been estimated to cause around 3.2 million deaths annually in 2019; these emissions also worsen ambient air quality, alter the global climate, have gendered livelihood impacts, and degrade the local environment.
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It estimates that there have been 228,000 additional deaths of children under five in these six countries [Afghanistan, Nepal, Bangladesh, India, Pakistan and Sri Lanka] due to crucial services, ranging from nutrition benefits to immunisation, being halted.
It says the number of children being tr...eated for severe malnutrition fell by more than 80% in Bangladesh and Nepal, and immunisation among children dropped by 35% and 65% in India and Pakistan respectively...
It also estimates that there have been some 3.5 million additional unwanted pregnancies, including 400,000 among teenagers, due to poor or no access to contraception...
The interruption to health services also affected those suffering from other diseases - the report predicts an additional 5,943 deaths across the region among adolescents who couldn't get treated for tuberculosis, malaria, typhoid and HIV/Aids.
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Supportive supervision is considered critical to community health worker programme performance, but there is relatively little understanding of how it can be sustainably done at scale. Supportive supervision is a holistic concept that encompasses three key functions: management (ensuring performance...), education (promoting development) and support (responding to needs and problems). Drawing on the experiences of the ward-based outreach team (WBOT) strategy, South Africa’s national community health worker (CHW) programme, this paper explores and describes approaches to supportive supervision in policy and programme guidelines and how these are implemented in supervision practices in the North West Province, an early adopter of the WBOT strategy. Outreach teams typically consist of six CHWs plus a nurse outreach team leader (OTL).
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The Practical manual on laboratory strengthening, 2022 update provides practical guidance on implementation of WHO recommendations and best practices for TB laboratory strengthening. It is an updated version of the GLI Practical Guide to Laboratory Strengthening published in 2017 and provides the la...test practical guidance on use of newly recommended diagnostics as well as guidance in key technical areas, including quality assurance and quality management systems, specimen collection and registration, procurement and supply-chain management, diagnostic connectivity, biosafety, data management, human resources, strategic planning, and model algorithms. The key changes are:
inclusion of recent or updated WHO recommendations for tests to diagnose TB and detect drug resistance;
alignment with the latest WHO critical concentrations for phenotypic drug-susceptibility testing (DST) and the new definitions of pre-XDR-TB and XDR-TB;
updated information on building quality-assured TB testing and management capacity using the Stepwise Laboratory Quality Improvement Process Towards Accreditation (SLIPTA) approach (Score-TB package1);
updated information on assessing, analysing and optimising TB diagnostic networks; and
updated information on the use of next-generation sequencing (NGS) to detect mutations associated with drug resistance for surveillance purposes.
The document also provides references to resources and tools relevant for work on laboratory strengthening.
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Human African trypanosomiasis (HAT) has been an alarming global public health issue. The disease affects mainly poor and marginalized people in low-resource settings and is caused by two subspecies of haemoflagellate parasite, Trypanosoma brucei and transmitted by tsetse flies. Progress made in HAT ...control during the past decade has prompted increasing global dialogue on its elimination and eradication. The disease is targeted by the World Health Organization (WHO) for elimination as a public health problem by 2020 and to terminate its transmission globally by 2030, along-side other Neglected Tropical Diseases (NTD). Several methods have been used to control tsetse flies and the disease transmitted by them. Old and new tools to control the disease are available with constraints.
Currently, there are no vaccines available. Efforts towards intervention to control the disease over the past decade have seen considerable progress and remarkable success with incidence dropping progressively, reversing the upward trend of reported cases. This gives credence in a real progress in its elimination. This study reviews various control measures, progress and a highlight of control issues, vector and parasite barriers that may have been hindering progress towards its elimination.
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Addressing comorbidities and risk factors for tuberculosis (TB) is a crucial component of the World Health Organization (WHO)’s End TB Strategy. This WHO operational handbook on tuberculosis. Module 6: tuberculosis and comorbidities aims to support countries in scaling up people-centred care, base...d on the latest WHO recommendations on TB and key comorbidities, and drawing upon additional evidence, best practices and inputs from various experts and stakeholders obtained during WHO processes. It is intended for use by people working in ministries of health, particularly TB programmes and the relevant departments or programmes responsible for comorbidities and health-related risk factors for TB such as HIV, diabetes, undernutrition, substance use, and tobacco use, as well as programmes addressing mental health and lung health. This operational handbook is a living document and will include a separate section for each of the key TB comorbidities or health-related risk factors. The third edition includes guidance for HIV-associated TB, mental health conditions and diabetes, which are three conditions strongly associated with TB and which result in higher mortality, poorer TB treatment outcomes and negatively impact health-related quality of life. The operational handbook aims to facilitate early detection, proper assessment and adequate management of people affected by TB and comorbidities. Full implementation of this guidance is expected to have a significant impact on TB treatment outcomes and health-related quality of life for people affected by TB.
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