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Publication Years
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Toolboxes
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WHO updated recommendations on HIV clinical management: recommendations for a public health approach
recommended

World Health Organization WHO (2025) C_WHO
This document provides an overview of the updated World Health Organization recommendations for HIV clinical management, which focus on optimizing antiretroviral therapy, preventing vertical transmission, and enhancing tuberculosis prevention among individuals with HIV. These updates are intended to ... more
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In-depth: What should behaviour change efforts look like in the PrEP era?

Molelekwa, T. Spotlight (2022) CC
what lessons can we take from the last few decades of health behaviour change efforts as we enter the era of HIV prevention pills, rings and injections?
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Guidance on handling interruptions in antiretroviral treatment due to HIV service disruptions, drug shortages, or stockouts
recommended

World Health Organization WHO (2025) C_WHO
Questions and answers. A key priority is preventing the interruption of current HIV treatment and prevention medicines. This Q&A outlines advice when this is not possible. Available in Arabic, Chinese, English, French, Portuguese, Russian and Spanish
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WHO guidelines on the management of advanced HIV disease
recommended

World Health Organization WHO (2025) C_WHO
These 2025 guidelines respond to the need for better approaches to identify advanced HIV disease, improve the poor outcomes of people living with HIV being discharged from hospital and provide updated guidance for treatment for Kaposi’s sarcoma through evidence-informed recommendations. The public ... more
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Adolescent HIV treatment

United Nations International Children's Emergency Fund UNICEF (2025) C_UNICEF
About six in ten adolescents 10-19 years of age living with HIV are on antiretroviral medications
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HIV - Paediatric care and treatment

United Nations International Children's Emergency Fund UNICEF (2025) C_UNICEF
Slightly more than half of children under 15 years of age living with HIV are on antiretroviral medications
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Guidelines for the Use of Antiretroviral Agents in Pediatric HIV Infection
recommended

Panel on Antiretroviral Therapy and Medical Management of Children Living with HIV (2025) C1
The information in the brief version is excerpted directly from the full-text guidelines. The brief version is a compilation of the tables and boxed recommendations. The guidelines were updated to comply with Executive Orders. You can download the full guidelines, charts and recommendations
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HIV in Adults: 2024 Recommendations of the International Antiviral Society–USA Panel

Gandhi RT, Landovitz RJ, Sax PE, et al. (2024) CC
JAMA. 2025;333(7):609–628. doi:10.1001/jama.2024.24543
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Time to HIV viral rebound and frequency of post-treatment control after analytical interruption of antiretroviral therapy: an individual data-based meta-analysis of 24 prospective studies

Gunst, J.D.; et al. (2025) CC
Nature communications, 16, 906 (2025). https://doi.org/10.1038/s41467-025-56116-1
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Q&A on the impact of the interruption of treatment for people living with HIV

UNAIDS (2025) CC
Recent suspensions and reductions in official development assistance (ODA) have posed significant challenges to HIV programme continuity in several countries. These funding disruptions have impacted people living with HIV and other vulnerable populations who rely on these essential services, like a ... more
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Dosing of LOPINAVIR/RITONAVIR for Children 2020

Ministry of Health, South Africa (2020) CC
Dosing of LPV/r by formulation & dose modification (RTV super-boosting/double-dose LPV/r) for children receiving rifampicin-containing TB treatment. Chart
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Antiretroviral Dosing Chart for Children

Ministry of Health, South Africa (2023) CC
Annexure 6 National Guidelines South Africa 2023
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Dolutegravir resistance very rare after a switch - even with detectable HIV

AIDSmap (2024) CC
The emergence of high-level dolutegravir resistance was extremely rare in people switched to first-line dolutegravir-based treatment in Zambia and Malawi, a large prospective study has found.
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What can modelling tell us about the scale-up of lenacapavir for pre-exposure prophylaxis?

UNAIDS (2025) C_WHO
Modelling shows that it will be essential to complement lenacapavir with additional prevention options, testing and treatment. See “Meeting reports” at https://www.unaids.org/en/resources/publications/all for a description of models and tools to estimate potential impact and quantifications requ ... more
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Use of dolutegravir-based regimens for first- and second-line antiretroviral therapy

Southern African HIV Clinicians Society (SAHCS) (2022) CC
Southern African HIV Clinicians Society (SAHCS) Clinical Update, May 2022
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Southern African HIV Clinicians Society 2023 Guideline for post-exposure prophylaxis: Updated recommendations

Horak, J.; et al. (2023)
Southern African Journal of HIV Medicine
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Multi-Month Dispensing (MMD) for Children and Adolescents Living with HIV

PEPFAR; USAID, Epic; et al. (2022) CC
A Guide for Community Case Workers in OVC Programs. This guide is meant to help you, a community case worker or facility case manager working on an orphans and vulnerable children (OVC) program, to understand your role in supporting multi-month dispensing (MMD) of anti-retroviral (ARV) medicines f ... more
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Oral PrEP Tool app
recommended
New

World Health Organization WHO (2026) C_WHO
The WHO PrEP Implementation Tool app for health workers Download IOS Download play store
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Oral Pre-Exposure Prophylaxis (PrEP) of HIV infection - eLearning tool for clinicians
recommended

World Health Organization WHO (2026) C_WHO
This eLearning course is for practicing health professionals around the globe who currently have a client population at high-risk for contracting HIV and provide or will provide Oral PrEP or Post-Exposure Prophylaxis (PEP). The course has four interactive lessons and begins with identifying suitable ... more
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Prevención Combinada del VIH con énfasis en PrEP Oral y de Acción Prolongada
recommended

World Health Organization WHO (2026) C_WHO
Este curso introduce la prevención combinada del VIH y la PrEP (profilaxis preexposición), brindando herramientas técnicas para su correcta implementación y seguimiento en la región.