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Publication Years
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Barbados currently has a rudimentary framework and capacity to address the issue of antimicrobial resistance. There however needs to be coordination of efforts and improvement in areas where gaps ha
...
ve been identified.Actions required include improved antibiotic stewardship in healthcare settings, prevention of the spread of drug-resistant organisms//bacteria, elimination of the use of medically-important antibiotics for growth promotion in food animals, and expanded surveillance for drug-resistant bacteria in humans and animals.
The National Action Plan will provide the roadmap to guide Barbados in the effort to address the urgent and serious threat of AMR and will be organized around three goals for collaborative action.
more
The consolidated guidelines are complemented by an operational handbook which is designed to assist with implementation of the WHO recommendations by Member States, technical partners and others who are involved in the management of patients with DR
...
-TB. The WHO Operational Handbook on Tuberculosis, Module 4: Treatment - Drug-Resistant Tuberculosis Treatment provides practical guidance on how to put in place the recommendations at the scale needed to achieve national and global impact.
The operational handbook provides practical information and tools that complement the recommendations in the guidelines. The strategies described in the operational handbook are based on the latest WHO recommendations which were formulated by Guideline Development Groups using the GRADE approach. In many cases however, the recommendations in their current form lacked sufficient clinical and programmatic detail, which is important for implementation. This operational handbook complements the guidelines with practical advice based on best practices and knowledge from the fields such as pharmacokinetics, pharmacodynamics, microbiology, pharmacovigilance and clinical and programmatic management.
more
Journal of Clinical TB and other Mycobacterial Diseases
uberculosis (TB) in the gastrointestinal tract or peritoneum is an uncommon condition in clinical practice. Its rarity, combined with its nonspecific presentations, makes this kind of extrapul
...
monary tuberculosis difficult to diagnose as it can mimic other inflammatory or malignant conditions. Delays in treatment and frequent misdiagnosis can lead to hazardous complications. In countries like Ecuador where the disease is endemic, TB should always be considered in the differential diagnosis of a patients who present with nonspecific abdominal symptoms. In these scenarios, laparoscopy can be an invaluable tool when used with sufficiently high clinical awareness and adequate training.
Case presentation
We present the case of a 37-year-old female patient from Ecuador with a 1-year history of abdominal pain, nausea, intermittent vomits, night sweats, and weight loss. After clinical evaluation and a laparoscopic intervention, abdominal TB was detected and promptly treated. Antituberculosis chemotherapy was initiated, and the patient successfully reco
High clinical awareness is imperative when approaching abdominal TB due to its wide spectrum of clinical symptoms and its rarity. Early detection and prompt treatment are critical to minimize the possibility of hazardous complications.
more
Available in Englisch, French, Spanish and Chinese
The document provides guidelines for the management of acute diarrhoea, highlighting improved oral rehydration solutions (ORS) with reduced osmolarity an
...
d zinc supplementation. It emphasizes their effectiveness in reducing the duration and severity of diarrhoeal episodes and preventing future cases. Aimed at families, communities, and healthcare professionals, it seeks to integrate these practices into routine care at home and in health centers.
more
Guidelines for essential trauma care
recommended
The Guidelines for essential trauma care seek to set achievable standards for trauma treatment services which could realistically be made available to almost every injured person in the world. They then seek to define the resources that would be nec
...
essary to assure such care. These include human resources (staffing and training) and physical resources (infrastructure, equipment and supplies).
more
Communities can play a critical role in suicide prevention. Facilitating community engagement in suicide prevention is an important task. The toolkit is a step-by-step guide for communities to engag
...
e in suicide prevention activities and have ownership of the process and keep efforts sustained. It is hoped that the pilot version will be used, after necessary adaptation, in many countries and contexts, so that the final product can be strengthened and become more effective and user-friendly.
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Areas for action include: increasing prioritisation and awareness of dementia; reducing the risk of dementia; diagnosis, treatment and care; suppor
...
t for dementia carers; strengthening information systems for dementia; and research and innovation.
more
In 2023, Breakthrough ACTION and Guyana’s Ministry of Health refined the 'Lil Mosquito, Big Problem' malaria campaign using human-centred design. Phase II introduced peer-led videos (Miners' Buzz), community champions, incentives for volunteer tes
...
ters and a transport network to improve supply delivery. These efforts enhanced engagement, coordination and timely reporting, reaching over 7,800 people. The campaign's innovative, community-driven approach has improved malaria prevention in remote mining regions.
Accessed on 20/06/2025.
more
Background: Atherosclerotic cardiovascular diseases (ASCVD) including myocardial infarction, stroke and peripheral arterial disease continue to be major causes of premature death, disability and hea
...
lthcare expenditure globally. Preventing the accumulation of cholesterol-containing atherogenic lipoproteins in the vessel wall is central to any healthcare strategy to prevent ASCVD. Advances in current concepts about reducing cumulative exposure to apolipoprotein B (apo B) cholesterol-containing lipoproteins and the emergence of novel therapies provide new opportunities to better prevent ASCVD. The present update of the World Heart Federation Cholesterol Roadmap provides a conceptual framework for the development of national policies and health systems approaches, so that potential roadblocks to cholesterol management and thus ASCVD prevention can be overcome.
more
Guidance for Immunization Programmes in the African Region in the Context of Ebola - Revised 30 March 2015*
World Health Organization
(2015)
Practical guidance on immunization services and the risks they present for both Ebola affected and non-affected countries. The specific purpose of this document is to assist countries to:
- Mai
...
ntain immunization services and use immunization contacts and surveillance system as opportunities to educate and monitor for Ebola;
- Provide guidance on infection prevention and control during vaccination;
- Prepare where there is a potential risk of Ebola (e.g. border, etc.) and low immunization coverage, to implement activities to increase immunization coverage in these areas.
more
Prepared as an outcome of ICMR Subcommittee on Breast Cancer |.This consensus document on management of breast cancers summarizes the
modalities of treatment including the site-specific anti-cancer therapies, supportive
...
and palliative care and molecular markers and research questions. It also interweaves clinical, biochemical and epidemiological studies.
more
In order to improve access to malaria services in remote mining areas of Guyana, the Ministry of Health and PAHO implemented a community case management programme, training workers in mining camps to test for
...
and treat uncomplicated malaria. However, formative research by Breakthrough ACTION Guyana found that awareness of these services among miners was low. In response, the project supported the development of social and behavioural change (SBC) interventions to increase the visibility of volunteer malaria testers (VMTs), strengthen their counselling skills and improve retention by recognising their contributions.
more
The document provides detailed guidelines for the production, formulation, and implementation of oral rehydration salts (ORS) to combat dehydration caused by diarrhoea, particularly in children. It focuses on the composition, quality standards,
...
and packaging requirements of ORS, aiming to support national authorities and healthcare providers in ensuring effective and accessible treatment. It also highlights strategies for manufacturing ORS locally while adhering to international health and safety standards.
more
The document provides guidance on managing acute diarrhoea outbreaks, specifically cholera and shigellosis. It outlines steps for identifying outbreaks, differentiating between cholera and shigellos
...
is, and treating patients based on the severity of dehydration. Recommendations include the use of oral rehydration solutions (ORS), antibiotics in severe cases, and strict hygiene practices to prevent transmission. The document also emphasizes community protection measures such as disinfection of water sources, isolation of cases, and proper food hygiene. It is a practical resource for health workers to quickly respond to diarrhoeal disease outbreaks.
more
The document provides guidance on managing acute diarrhoea outbreaks, specifically cholera and shigellosis. It outlines steps for identifying outbreaks, differentiating between cholera and shigellos
...
is, and treating patients based on the severity of dehydration. Recommendations include the use of oral rehydration solutions (ORS), antibiotics in severe cases, and strict hygiene practices to prevent transmission. The document also emphasizes community protection measures such as disinfection of water sources, isolation of cases, and proper food hygiene. It is a practical resource for health workers to quickly respond to diarrhoeal disease outbreaks.
more
Long-lasting insecticidal nets (LNs) constitute a core vector control intervention against malaria. A number of new LN products are under development and will require assessment of risks to humans. This document provides an updated generic model tha
...
t can be used for the risk assessment of exposure to insecticides of individuals sleeping under LNs and during the washing of nets.
In an Annex, exposures and health risks are described for the conventional treatment or retreatment of nets (ITNs) with an insecticide considering that such practices may still be used in evaluation of ITNs and their use. The generic model does not include the risks associated with the manufacturing of LNs in a factory environment. more
In an Annex, exposures and health risks are described for the conventional treatment or retreatment of nets (ITNs) with an insecticide considering that such practices may still be used in evaluation of ITNs and their use. The generic model does not include the risks associated with the manufacturing of LNs in a factory environment. more
This video highlights the significant risks that malaria poses to pregnant and breastfeeding women in malaria-endemic regions. It follows the stories of Angavu from Kenya, Moyinoluwa from Nigeria and
...
Lamai from Thailand. It emphasises the severe consequences that malaria can have during pregnancy, including miscarriage, stillbirth, low birth weight and maternal death. Due to safety concerns, pregnant women are often excluded from antimalarial drug trials, which causes long delays in effective medicines becoming available for this vulnerable group. To address this issue, the Medicines for Malaria Venture (MMV) launched the Malaria in Mothers and Babies (MiMBa) initiative, which aims to accelerate the discovery, development, and delivery of safe antimalarial treatments for pregnant and breastfeeding women. The initiative aims to close critical gaps in research, drug development, and access, ensuring that these women and their babies are better protected against malaria. The video calls for continued efforts to address the needs of underserved populations most affected by malaria.
more
The Malaria Operational Plans below are detailed 1-year implementation plans for PMI focus countries. Each plan reviews the current status of malaria control and prevention policies
...
and interventions, identifies challenges and unmet needs to achieve PMI goals, and provides a description of planned PMI-funded activities.
more
The purpose of the PAS III is to guide Pakistan’s overall national response for HIV and AIDS through 2020, through focused interventions with set targets, costs, roles and responsibilities. The su
...
ccessful implementation of PAS III involves multiple stakeholders to achieve priority outcomes outlined in the Strategy. The Strategy focuses on allocating limited resources to scale up high-impact, high-value interventions such as HTC and treatment to reduce AIDS related deaths and new HIV infections. Priorities in the PAS III have been identified to ensure maximum impact in reducing new infections, especially among key populations, improving treatment uptake and retention, and improving the quality of life of people living with HIV and AIDS in the context of limited financial and human resources.
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