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Clinical Pharmacology: Advances and Applications, 2025:17 29–47
The 'Zzippi Drinks Blood' booklet is designed to be used as a teaching aid by health educators. It can be used to support malaria prevention teaching sessions and displayed on walls to help children remember the key messages. The illustrations can also be copied and used to create flashcards or a fl
...
ipbook, facilitating interactive learning. Educators are encouraged to adapt the content to suit their local context, and to consult experts to ensure accuracy.
Accessed on 14/07/2025.
more
Le Infezioni in Medicina, n. 1, 3-10, 2019
The ongoing global pandemic of SARS-CoV-2 (Covid-19) poses unique diagnostic and clinical management challenges in regions where seasonal epidemic-prone diseases are endemic. Diseases such as dengue, malaria, seasonal influenza, leptospirosis, chikungunya, scrub typhus and bacterial infections often
...
present with febrile syndromes that mimic or co-exist with SARS-CoV-2 infection, complicating diagnosis and treatment. This document provides guidelines for preventing, diagnosing and managing such co-infections. A high level of suspicion is essential during the monsoon and post-monsoon seasons, taking into account region-specific disease prevalence. While the WHO's case definition for SARS-CoV-2 is broad and sensitive, the need for parallel testing for co-infections, in accordance with the protocols of the MoHFW, ICMR, NVBDCP and NCDC, is necessitated by overlapping clinical features. Ensuring the availability of reliable rapid diagnostic kits and applying integrated clinical and laboratory approaches are crucial to improving patient outcomes in the context of concurrent infections.
Accessed on 26/08/2025.
more
The 2022 report reviews the global malaria diagnostics market and technological landscape to support Unitaid’s 2023–2027 strategy for quality malaria case management. The report highlights the stalled progress of malaria control efforts, the gaps in access to diagnostics and the public health im
...
plications of P. falciparum HRP2/3 gene deletions, which compromise the accuracy of the widely used HRP2-detecting rapid diagnostic tests (RDTs). The report analyses the malaria RDT market, noting supplier diversification, price trends and production shifts resulting from the pandemic. It also addresses the emerging point-of-care G6PD testing market, which is required to ensure the safe radical cure of P. vivax infections. It surveys technological innovation, including digital microscopy, hemozoin tests, nucleic acid detection and biosensors, while emphasising that RDTs and microscopy will remain the mainstay of case management in the near term. The report identifies market shortcomings, access barriers and opportunities to improve malaria case management and diagnostic coverage.
more
In 2022, a total of 6,131 confirmed malaria cases were reported across the EU/EEA. Of these, 5,375 had a known importation status and nearly all (99.8%) were travel-related. Only 13 infections were acquired within Europe, with seven occurring in France, three in Germany, two in Spain and one in Irel
...
and. A distinct seasonal peak was observed from July to September, reflecting travel to malaria-endemic regions. Notification rates were higher among men than women, with a male-to-female ratio of 2:1. France reported the highest number of cases, followed by Germany, Spain, Italy and Belgium. After dropping sharply in 2020 due to travel restrictions imposed during the pandemic, overall notification rates increased again in 2021 and 2022, reaching 0.8 cases per 100,000 people. These findings emphasise that malaria in Europe is predominantly an imported disease closely linked to international travel, with sporadic local transmission being rare.
more
This guidance synthesizes current evidence on dengue laboratory testing and diagnostics and provides practical recommendations for laboratories, clinicians, public health officials, and programme managers involved in dengue diagnosis, surveillance, and control, in the context of the global emergency
...
. It includes a diagnostic algorithm for suspected cases, outlining appropriate testing methods based on days post symptom onset.
more
On 13 August 2024, the Africa Centres for Disease Control (Africa CDC) declared the multi-country mpox outbreak a public health emergency of continental security, with strong recommendations to improve surveillance and vaccine deployment in all AU Member States. On 14 August 2024, the WHO Director-G
...
eneral declared mpox outbreak a public health emergency of international concern (PHEIC).
more
The ILO has joined forces with Gallup to carry out a groundbreaking global survey covering 50 countries that sheds further light on the causes of the persistence of HIV-related stigma and discrimination in the world of work.
The findings of the report are both urgent and devastating. At the current rate of progress, by 2040 we would still have 1.9 million new HIV infections and 990,000 AIDS-related deaths in children. But if funding for HIV prevention and treatment continues to fall as current trends suggest, the world
...
could face an additional 1.1 million new HIV infections and 820,000 additional deaths by 2040. In this worst-case scenario, by 2040, three million children would acquire HIV and nearly 1.8 million would die of AIDS-related causes — the vast majority in sub-Saharan Africa. These are not statistics; they are children with dreams, families, and futures. They represent our shared humanity — and our collective failure if we do not act.
more
The document provides guidance and tools for training health professionals in outbreak investigation. It explains why such training is essential, outlines the methodology for conducting short, practical courses, and describes how lectures, case studies, and exams are used to build skills needed for
...
detecting, investigating, and responding to public health events. It also details how to plan, organize, and implement the training, including required resources, team roles, and evaluation procedures.
more
In 2022, WHO published the Consolidated guidelines on HIV, viral hepatitis and STI prevention, diagnosis, treatment and care for key populations. These guidelines outline a public health response to HIV, viral hepatitis and sexually transmitted infections (STIs) for 5 key populations (men who have s
...
ex with men, sex workers, people in prisons and other closed settings, people who inject drugs and trans and gender diverse people).
In this policy brief, we give an update on those parts of the guidelines related to hepatitis C diagnosis and treatment for key populations.
more
Information Sheet
EDCTP Stakeholder meeting
This document is itended as a quick guide of healtcare workers involved in clincial management
Essential triple EMTCT services include testing for HIV, syphilis and HBV in ante-
natal care (ANC) settings; prompt and efficacious interventions to treat women
who test positive; prevent transmission of any of the infections to their children;
counseling for women and their partners to reduce t
...
ransmission risk and ensure
appropriate treatment; encourage clean and safe delivery; appropriate follow
up of exposed infants including provision of HBV vaccine birth dose; promoting
optimal infant-feeding; and lifelong treatment and care for mothers living with
HIV or those eligible for treatment for hepatitis B infections and treatment for
syphilis.
more
Bhana A et al. Journal of the International AIDS Society 2021, 24(S2):e25713
2024 Global HIV Estimates on children, adolescents and pregnant women.
Lwamaba, C., and S. Brar
United Nations International Children's Emergency Fund UNICEF
(2024)
C_UNICEF
Presentation Slides
Data for Global Pandemic and Epidemic Intelligence
Fitzner, J.; – WHO Hub for Pandemic and Epidemic Intelligence
World Health Organization (WHO)
(2025)
C_WHO
The presentation “Data for Global Pandemic and Epidemic Intelligence” outlines how improved data collection, surveillance, analytics, and digital tools can strengthen global preparedness and response to health emergencies. It explains the concept of epidemic intelligence, highlighting the integr
...
ation of multiple data sources—such as traditional surveillance, genomics, open-source information, and modelling—to support timely and evidence-based decision-making. The presentation also showcases initiatives of the WHO Hub for Pandemic and Epidemic Intelligence, including collaborative data platforms, pathogen genomics networks, analytic communities of practice, and a decision-support pandemic simulator designed to enhance rapid, coordinated responses to future outbreaks.
more
The WHO publication “Surveillance, case investigation and contact tracing for mpox: interim guidance” provides updated global technical guidance on monitoring and responding to mpox (formerly known as monkeypox). It explains how countries should conduct surveillance to detect new outbreaks, car
...
ry out case investigation including clinical assessment and lab specimen collection, and perform contact tracing to monitor people exposed to confirmed or probable cases in order to stop transmission and protect at-risk groups. The guidance includes practical recommendations for how long contacts should be monitored (e.g., daily for 21 days without requiring quarantine if symptom-free) and advising good hygiene and reduced exposure risk during the monitoring period. This interim guidance is intended to support public health authorities worldwide in strengthening mpox outbreak detection, response, and reporting.
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