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The global prevalence, morbidity and mortality related to childhood asthma among children has increased significantly over the last 40 years. Although asthma is recognized as the most common chronic disease in
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children, issues of underdiagnosis and undertreatment persist. There are substantial global variations in the prevalence of asthma symptoms in children, with up to 13-fold differences between countries. The rising number of hospital admissions for asthma may reflect an increase in asthma severity, poor disease management and/or the effect of poverty. The financial burden of asthma is relatively high within developed countries (those for which data is available) spending 1 to 2% of their healthcare budget on this condition. Established in 1989, the Global Initiative for Asthma (GINA) attempts to raise awareness about the increasing prevalence of asthma, improve management and reduce the burden of asthma worldwide. Despite global efforts, GINA has not achieved its goal, even among developed nations. There are multiple barriers to reducing the global burden of asthma, including limited access to care and/or medications, and lack of prioritization as a public healthcare priority. In addition, the diversity of healthcare systems worldwide and large differences in access to care require that asthma management guidelines be tailored to local needs.
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This video is of a community performance from a theatre play, called 'In Control' South Africa. Our international group of respiratory health researchers found that young people with asthma can feel stigmatised or misunderstood. We therefore developed ths play together with a UK young people's theat
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re (Tramshed) and a local theatre group (Assitej).
The play is about a teenage girl with asthma, who struggles with different perceptions and prejudices people have of her condition. This play has been developed as part of a wider research project across sub-Saharan Africa, called ACACIA (Achieving Control of Asthma in Children in Africa).
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Asthma has a significant impact on people of all ages, particularly children. A lack of universally accepted case definition and confirmatory tests and a poor understanding of major risks interfere with a global response. We aimed to provide global
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estimates of asthma prevalence and cases in 2019 across four main epidemiological case definitions – current wheezing, ever wheezing, current asthma, and ever asthma. We further investigated major associated factors to determine regional and national distributions of prevalence and cases for current wheezing and ever asthma.
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Demographic and epidemiological transitions are changing the age structure of the population and the most common diseases. Non-communicable respiratory diseases are an increasing problem at both ends of the age range in low-income and middle-income countries. In
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children, who represent a large proportion of the total population, the increasing problem of asthma is a strain on health services. Improved survival of the older population is increasing the proportion of morbidity and mortality attributable to chronic lung diseases. Health services in low-resource countries are poorly adapted to treating chronic diseases. Designed to respond episodically to acute disease, almost all historical investment has focused on infectious diseases. Crucial to the successful management of chronic diseases is an infrastructure designed to support pro-active management, providing not only an accurate diagnosis, but also a secure supply of cost effective drugs at an affordable price. The absence of such an infrastructure in many countries and the market failure that makes drugs generally more expensive in low-resource regions means that many people with chronic non-communicable lung diseases are not given effective treatment. This has damaging economic consequences. The common causes of poor lung health in lowincome countries are not the same as those in richer countries, and there is a need to study why they are so common and how best to manage them.
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Chronic respiratory diseases (CRDs) are among the leading causes of death worldwide, with asthma rated the most common chronic disease affecting children (1). Globally, about 300 million people have asthma, and current trends suggest that an additio
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nal 100 million people may be living with asthma by 2025.
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Social protection programmes in Malawi ensure that those most in need get the essential assistance they require.Social protection programmes help the most vulnerable, including the elderly, ultra-poor, disabled, and children
The IAPB School Eye Health Workgroup has released these guidelines to help deliver standardised comprehensive eye health services to more than 700 million children attending schools around the world. These guidelines direct the planning and implemen
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tation of school eye health initiatives for policymakers, health authorities, and related professionals. They emphasize effective, efficient, and sustainable programs, particularly in low- and middle-income countries. Monitoring and evaluation should be planned from the outset, and existing local guidelines should be integrated.
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Over the course of their lives, women spend more time with children than men. Because young children are the reservoirs of trachoma infection, contact with them can result in more frequent trachoma
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infection. This gender-specific exposure to trachoma risk factors places women at a higher risk for trachoma infections and subsequent blindness. Although both men and women can develop trichiasis, the odds of trichiasis are greater among women than men.
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This document sets out key messages to support malaria prevention and control efforts, for teachers, pupils and the wider community. It is designed to facilitate health education in schools by encouraging teachers to guide pupils through the core messages about malaria and emphasise the most importa
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nt points. Pupils are expected to actively engage by taking notes and applying what they learn. Ultimately, the goal is to equip children with the practical knowledge to influence behavioural change at both the individual and community levels.
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WASH 4 All 1 is an educational comic designed to raise awareness of water, sanitation and hygiene practices. Through engaging illustrations and simple language, it educates communities, especially children and families, about the importance of clean
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water, proper sanitation and good hygiene in improving health outcomes. The booklet is a practical tool that can be used by educators and health promoters to encourage behavioural change in a variety of settings.
Accessed on 20/06/2025.
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The WHO recommends parenteral artesunate over quinine and artemether for treating severe Plasmodium falciparum malaria in adults and children. Intravenous administration is preferred. A new one-step, arginine-based formulation eliminates the need fo
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r dilution steps, reducing errors and accelerating the initiation of treatment—a critical factor for survival. This formulation was first prequalified by the WHO in 2023. By contrast, the conventional two-step artesunate formulation, which was prequalified in 2010, requires more complex preparation. Clear guidance is essential, as product-specific protocols differ. These training materials aim to support the correct and effective administration of the medication.
Accessed on 27/06/2025.
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The Zambia Malaria Campaign, implemented by Breakthrough ACTION, used culturally tailored radio adverts and a campaign song to encourage key behaviours for preventing and treating malaria. The campaign targeted high-risk groups, such as pregnant women and caregivers of
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children under five, and delivered messages in multiple local languages, including English, Siswati and Tonga. The audio content encouraged the consistent use of insecticide-treated nets (ITNs), seeking timely care for fevers, and preventing malaria during pregnancy. Through addressing common myths and promoting positive social norms in an engaging way, the campaign aimed to increase community knowledge and encourage long-lasting behavioural change in malaria-endemic regions of Zambia.
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Malaria remains a significant public health concern, particularly in sub-Saharan Africa, where the majority of cases and fatalities occur, especially among children under five. Although there was a significant decline in global mortality and inciden
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ce between 2000 and 2015, progress has stalled since the late 2010s due to climate change, conflict, drug and insecticide resistance, and the ongoing effects of the pandemic. Economic modelling shows that achieving the Sustainable Development Goal target of reducing malaria incidence by 90% by 2030 could generate substantial economic benefits, including an increase in GDP of $142.7 billion in endemic countries and $80.7 billion in global trade gains. To save lives, strengthen health systems, and drive sustainable economic growth, renewed investments in malaria control and elimination programmes, vaccine deployment, and coordinated international support are essential.
Accessed on 25/08/2025.
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This table summarises the drugs used for malaria prevention, including adult and paediatric dosages, timing and special considerations. The medications listed are atovaquone/proguanil, chloroquine, doxycycline, hydroxychloroquine, mefloquine, primaquine and tafenoquine. The guidance covers the use o
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f these drugs for primary and terminal prophylaxis, as well as contraindications (e.g. G6PD deficiency, pregnancy, and psychiatric or cardiac conditions) and safety precautions for children and special populations. The aim is to help travellers and healthcare providers reduce the risk of malaria during travel.
Accessed on 27/08/2025.
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Malaria remains a significant global health concern, with 249 million cases and 408,000 deaths reported in 2022, primarily in sub-Saharan Africa. The most vulnerable populations are children under five and pregnant women. Rapid and accurate diagnosi
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s using microscopy or malaria rapid diagnostic tests (mRDTs) is essential to ensure timely treatment, prevent severe disease and promote the rational use of antimalarial drugs. This UNICEF Technical Bulletin provides guidance on the procurement, quality assurance and selection of WHO-prequalified mRDTs, including considerations for areas with a high prevalence of pfhrp2/3 gene deletions. The bulletin also highlights UNICEF’s approach to sustainability, product verification and long-term arrangements with manufacturers, which ensure a reliable supply while supporting integrated child health management programmes. The bulletin serves as a valuable resource for countries, partners and programmes involved in the implementation of malaria case management and diagnostics.
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In: Antenatal Care, Maternal Care, Under 5 Clinics, Family Planning Clinics and HIV Exposed Child Follow Up.
This 5th Edition of the Malawi Guidelines for Clinical Management of HIV in Children and Adults is implemented from January 2022. It replac
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es all previous editions of the Malawi Antiretroviral therapy (ART) and Prevention of Mother to Child Transmission (PMTCT) guidelines.This document is written for medical doctors, clinical officers, medical assistants, nurses, midwives, laboratorians, health surveillance assistants (HSAs) and medical records clerks who are working in public and private sector health facilities in Malawi. It is designed to be a practical guide for implementation of integrated HIV Services
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A manual for physicians and other senior health workers. This fourth revision of the manual reflects recent clinical experience and research findings in diarrhoea case management. Compared to earlier versions, it includes revised guidelines on the management of
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children with acute diarrhoea using the new reduced (low) osmolarity ORS formulation and using zinc supplements, which have been shown to reduce duration and severity of diarrhoeal episodes, and revised guidelines for the management of bloody diarrhoea. Guidelines in the manual are based on the revised WHO chart that are included at the end of this document.
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Facts For Life
recommended
Handbook on pregnancy, childbirth, childhood illnesses, child development and the care of children. The handbook, Facts for Life, provides vital messages and information for mothers, fathers, other family members and caregivers and communities to us
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e in changing behaviours and practices that can save and protect the lives of children and help them grow and develop to their full potential.
This version of Facts for Life builds on the three previous editions, which have been helping families and communities around the world since 1989. Newborn Health has been added to the Safe Motherhood chapter, giving attention to child survival from the first stage of life. A new chapter, Child Protection, has been included, focusing attention on the actions needed to ensure children grow up in protective environments.
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Tuberculosis. Practical guide for clinicians, nurses, laboratory technicians and medical auxiliaries
This Tuberculosis guide has been developed jointly by Médecins Sans Frontières and Partners In Health. It aims at providing useful information to the clinicians and health staff for the comprehensive management of tuberculosis. Forms of susceptible and resistant tuberculosis, tuberculosis in
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children, and HIV co-infection are all fully addressed.
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