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End-to-end integration of SARS-CoV-2 and influenza sentinel surveillance: revised interim guidance

World Health Organization WHO (2022) C_WHO

This guidance provides interim guidance for the integration of SARS-CoV-2 and influenza virologic and genomic surveillance, from sentinel site case enrolment and sampling to the eventual sharing of the virus sequence data, a process known as end-to-end surveillance. This guidance builds on experienc... more

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Ambient (outdoor) air pollution - arabic version

World Health Organization (WHO) World Health Organization (WHO) (2022) C_WHO

The World Health Organization (WHO) fact sheet on ambient (outdoor) air quality and health highlights the significant health risks posed by outdoor air pollution. It reports that in 2019, ambient air pollution was responsible for approximately 4.2 million premature deaths globally, primarily due to ... more

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Ambient (outdoor) air pollution

World Health Organization (WHO) World Health Organization (WHO) (2022) C_WHO

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Wits RHI’s Key responses to COVID-19

University of Witwatersrand (2020) C2

Wits Reproductive Health and HIV Institute (Wits RHI) is involved in an effort to curb the COVID-19 pandemic that is facing South Africa and the world at large. Prof. Helen Rees is a member of the team advising the Health Minister on COVID-19 (MAC). She is part of the Clinicians Group, the Research ... more

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GIEWS Country Brief Lesotho (December 2017)

Food and Agricultural Organisation of the United Nations (FAO) (2017) C1

Global Information and Early Warning System on Food and Agriculture (GIEWS)

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Clinical management of diphtheria: guideline

World Health Organization WHO (2024) C_WHO

WHO has published the first-ever guidance on the clinical management of diphtheria. The only previously available guidance was an operational protocol. The new guidance followed the rigorous process for developing guidance at WHO. It addresses the use of Diphtheria Antitoxin (DAT) in the treatmen... more

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Air Pollution - WHO

World Health Organisation (WHO) (2022) C_WHO

Accessed on 06.03.2022 Air pollution is contamination of the indoor or outdoor environment by any chemical, physical or biological agent that modifies the natural characteristics of the atmosphere. Household combustion devices, motor vehicles, industrial facilities and forest fires are common sou... more

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Best practices for haemoglobin measurement in population-level anaemia surveys: Technical brief (January 2024)

World Health Organization WHO; UN Children´s Fund UNICEF (2024) CC

Anaemia is a serious global public health problem that particularly affects young children, menstruating adolescent girls and women, and pregnant and postpartum women. It is a condition in which the number of red blood cells or the haemoglobin concentration within them is lower than normal, affectin... more

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Cardiovascular disease risk profile and management practices in 45 low-income and middle-income countries: A cross-sectional study of nationally representative individual-level survey data

Peiris, D.; Ghosh, A.; Manne-Goehler, J. et al. PLoS Medicine (2021) CC

Global cardiovascular disease (CVD) burden is high and rising, especially in low-income and middle-income countries (LMICs). Focussing on 45 LMICs, we aimed to determine (1) the adult population’s median 10-year predicted CVD risk, including its variation within countries by socio-demographic char... more

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Diabetes prevention, screening and management

International Pharmaceutical Federation (2021) CC2

Diabetes is a significant public health issue that affects approximately one in 10 adults globally, with type 2 diabetes accounting for 90–95% of cases. This chronic condition causes considerable morbidity and mortality and is growing in impact, with cases projected to rise from 537 million in 202... more

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No time to lose: Universal health coverage and the growing burden of non-communicable diseases

NCD Alliance American College of Cardiology - NCD Academy (2023) CC2

The NCD Alliance website provides information and resources on preventing and controlling non-communicable diseases (NCDs), including cardiovascular diseases, cancer, respiratory diseases, diabetes, and mental health conditions. The Alliance advocates for global health policies, supports countries i... more

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Funding the future of the HIV response

The Lancet Editorial (2022) CC

Substantial progress in the fight against HIV has been made over the past decade. Advances in HIV prevention, testing, and treatment have been matched by declines in HIV incidence and HIV-related deaths. The success of Botswana reaching the 95-95-95 targets, despite resource limitations, points to a... more

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Assessing national capacity for the prevention and control of noncommunicable diseases: report of the 2019 country capacity survey in the Eastern Mediterranean Region

World Health Organization (WHO) World Health Organization (WHO) (2023) C_WHO

The report "Assessing National Capacity for the Prevention and Control of Noncommunicable Diseases" provides an overview of the capacities of countries in the Eastern Mediterranean Region to address noncommunicable diseases (NCDs) based on a 2019 survey. It evaluates the progress of 22 countries in ... more

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Current epidemiological evidence for predisposition to high or low intensity human helminth infection: a systematic review

Wright J.E., Werkman M., Dunn J.C. et al Parasites and Vectors (2018) C2

Background: The human helminth infections include ascariasis, trichuriasis, hookworm infections, schistosomiasis, lymphatic filariasis (LF) and onchocerciasis. It is estimated that almost 2 billion people worldwide are infected with helminths. Whilst the WHO treatment guidelines for helminth infecti...ons are mostly aimed at controlling morbidity, there has been a recent shift with some countries moving towards goals of disease elimination through mass drug administration, especially for LF and onchocerciasis. However, as prevalence is driven lower, treating entire populations may no longer be the most efficient or cost-effective strategy. Instead, it may be beneficial to identify individuals or demographic groups who are persistently infected, often termed as being “predisposed” to infection, and target treatment at them. Methods: The authors searched Embase, MEDLINE, Global Health, and Web of Science for all English language, humanbased papers investigating predisposition to helminth infections published up to October 31st, 2017. The varying definitions used to describe predisposition, and the statistical tests used to determine its presence, are summarised. Evidence for predisposition is presented, stratified by helminth species, and risk factors for predisposition to infection are identified and discussed. Results: In total, 43 papers were identified, summarising results from 34 different studies in 23 countries. Consistent evidence of predisposition to infection with certain species of human helminth was identified. Children were regularly found to experience greater predisposition to Ascaris lumbricoides, Schistosoma mansoni and S. haematobium than adults. Females were found to be more predisposed to A. lumbricoides infection than were males. Household clustering of infection was identified for A. lumbricoides, T. trichiura and S. japonicum. Ascaris lumbricoides and T. trichiura also showed evidence of familial predisposition. Whilst strong evidence for predisposition to hookworm infection was identified, findings with regards to which groups were affected were considerably more varied than for other helminth species. Conclusion: This review has found consistent evidence of predisposition to heavy (and light) infection for certain human helminth species. However, further research is needed to identify reasons for the reported differences between demographic groups. Molecular epidemiological methods associated with whole genome sequencing to determine ‘who infects whom’ may shed more light on the factors generating predisposition. more

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UNEP: Environmental Data Explorer

United Nations Environment Programme (UNEP) (2019) CC

The Environmental Data Explorer is the authoritative source for data sets used by UNEP and its partners in the Global Environment Outlook (GEO) report and other integrated environment assessments. Its online database holds more than 500 different variables, as national, subregional, regional and glo... more

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An economic investment case & financing requirements

ACT-Accelerator: An economic investment case & financing requirements (2021) C_WHO

This document lays out economic arguments for investing in the Access to COVID-19 Tools Accelerator (ACT-Accelerator). Framed within an overall context that recognizes the broader human health and societal impacts of the COVID-19 crisis, ACT-Accelerator's Economic Investment Case argues that investm... more

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From animal use to a mainstay treatment against intestinal worms in humans

World Health Organization WHO (2023) C_WHO

Website last accessed on 14.04.2023 One of the ongoing challenges with neglected tropical diseases (NTDs) is that the discovery of medicines to treat them has been very slow. Current global programmes for NTDs largely depend on donated medicines, primarily to treat the world’s poorest people �... more

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Gender and COVID-19

World Health Organisation (2020) C_WHO

Pandemics and outbreaks have differential impacts on women and men. From risk of exposure and biological susceptibility to infection to the social and economic implications, individuals’ experiences are likely to vary according to their biological and gender characteristics and... more

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2014 Nutrition Country Profile Uganda

International Food Policy Research Institute (2014) C1

Global Nutrition Report

First WHO report details devastating impact of hypertension and ways to stop it

World Health Organization WHO (2023) C_WHO

The World Health Organization (WHO) released its first-ever report on the devastating global impact of high blood pressure, along with recommendations on the ways to win the race against this silent killer. The report shows approximately 4 out of every 5 people with hypertension are not adequately t... more