Profile of Crisis Response of District Health / Disaster Risk: District of South Central Timor, Indonesia
Profile of health crisis response in potential areas of natural disaster in Indonesia : District of East Barito
The cardiovascular disease continuum begins with risk factors such as diabetes mellitus (DM), progresses to vasculopathy and myocardial dysfunction, and finally ends with cardiovascular death. Diabetes is associated with a 2- to 4-fold increased risk for heart failure (HF). Moreover, HF patients wit...h DM have a worse prognosis than those without DM. Diabetes can cause myocardial ischemia via micro- and macrovasculopathy and can directly exert deleterious effects on the myocardium. Hyperglycemia, hyperinsulinemia, and insulin resistance can cause alterations in vascular homeostasis. Then, reduced nitric oxide and increased reactive oxygen species levels favor inflammation leading to atherothrombotic progression and myocardial dysfunction. The classification, diagnosis, and treatment of HF for a patient with and without DM remain the same. Until now, drugs targeting neurohumoral and metabolic pathways improved mortality and morbidity in HF with reduced ejection fraction (HFrEF). Therefore, all HFrEF patients should receive guideline-directed medical therapy. By contrast, drugs modulating neurohumoral activity did not improve survival in HF with preserved ejection fraction (HFpEF) patients. Trials investigating whether sodium-glucose cotransporter-2 inhibitors are effective in HFpEF are on-going. This review will summarize the epidemiology, pathophysiology, and treatment of HF in diabetes.
more
Profile of Health Crisis Response within District with High Disaster Risk: District of Kapuas, Indonesia
WHO has published the first-ever guidance on the clinical management of diphtheria. The only previously available guidance was an operational protocol. The new guidance followed the rigorous process for developing guidance at WHO.
It addresses the use of Diphtheria Antitoxin (DAT) in the treatmen...t of diphtheria. There is a worldwide shortage of DAT and evidence based recommendations on the use of DAT were requested by many Member States.
The guidance also includes new recommendations on antibiotics. In patients with suspected or confirmed diphtheria, WHO recommends using macrolide antibiotics (azithromycin, erythromycin) rather than penicillin antibiotics.
This clinical practice guideline has been rapidly developed recognizing the global increase in diphtheria outbreaks. Outbreaks of diphtheria in Nigeria, Guinea and neighbouring countries in 2023 have highlighted the urgent need for evidence-based clinical practice guidelines for the treatment of diphtheria. Given the sporadic nature of outbreaks, many clinicians in the affected regions have never managed acute diphtheria and its related complications. Diphtheria remains a neglected disease and vaccination is the top priority. At the same time, for patients with diphtheria, access to antibiotics, DAT and supportive care can be lifesaving.
more
Profile of health crisis response of district, area or cities in Indonesia with high risk of natural disaster : Kutai City, Indonesia
Profile of Health Crisis Response within District with High Risk of Natural Disaster : District of Morotai Island, Indonesia
Profile of Crisis Response of District Health or Disaster Risk at East Halmahera District, Indonesia
Profile of Crisis Response of District Health / Disaster Risk: Regency of Pulang Pisau, Indonesia
This publication was developed in response to the need for a reference list of priority medical devices required for management of noncommunicable diseases (NCDs), focusing on cardiovascular diseases and diabetes, especially for low- and middle-income countries to support universal health coverage a...ctions.
more
Profile of health crisis response of area, city or district in indonesia with high risk of natural disaster : Bengkulu City, Indonesia
Profile of health crisis response of cities, area or districts in Indonesia with high risk of natural disaster : District of Kolaka, Indonesia
Cureus 2024 Jan 16;16(1):e52358. doi: 10.7759/cureus.52358
Profile of Health Crisis Response within District with High Risk of Natural Disaster : District of Middle Halmahera, Indonesia
Profile of Health Crisis Response within District with High Risk of Natural Disaster : District of Sambas, Indonesia
Profile of Health Crisis Response within District with High Risk of Disaster : West Halmahera-District, Indonesia
Profile of Health Crisis Response within District with High Risk of Natural Disaster : District of Lebong, Indonesia