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Therapeutics and COVID-19 (Living Guideline, 10 November 2023)

World Health Organization WHO (2023) C_WHO

WHO has updated its guidelines for COVID-19 therapeutics, with revised recommendations for patients with non-severe COVID-19. This is the 13th update to these guidelines. Updated risk rates for hospital admission in patients with non-severe COVID-19 The guidance includes updated risk rates for... hospital admission in patients with non-severe COVID-19. The current COVID-19 virus variants tend to cause less severe disease while immunity levels are higher due to vaccination, leading to lower risks of severe illness and death for most patients. This update includes new baseline risk estimates for hospital admission in patients with non-severe COVID-19. The new ‘moderate risk’ category now includes people previously considered to be high risk including older people and/or those with chronic conditions, disabilities, and comorbidities of chronic disease. The updated risk estimates will assist healthcare professionals to identify individuals at high, moderate or low risk of hospital admission, and to tailor treatment according to WHO guidelines: **High: **People who are immunosuppressed remain at higher risk if they contract COVID-19, with an estimated hospitalization rate of 6%. **Moderate: **People over 65 years old, those with conditions like obesity, diabetes and/or chronic conditions including chronic obstructive pulmonary disease, kidney or liver disease, cancer, people with disabilities and those with comorbidities of chronic disease are at moderate risk, with an estimated hospitalization rate of 3%. Low: Those who are not in the high or moderate risk categories are at low risk of hospitalization (0.5%). Most people are low risk. Review of COVID-19 treatments for people with non-severe COVID-19 WHO continues to strongly recommend nirmatrelvir-ritonavir (also known by its brand name ‘Paxlovid’) for people at high-risk and moderate risk of hospitalization. The recommendations state that nirmatrelvir-ritonavir is considered the best choice for most eligible patients, given its therapeutic benefits, ease of administration and fewer concerns about potential harms. Nirmatrelvir-ritonavir was first recommended by WHO in April 2022. If nirmatrelvir-ritonavir is not available to patients at high-risk of hospitalization, WHO suggests the use of molnupiravir or remdesivir instead. WHO suggests against the use of molnupiravir and remdesivir for patients at moderate risk, judging the potential harms to outweigh the limited benefits in patients at moderate risk of hospital admission. For people at low risk of hospitalization, WHO does not recommend any antiviral therapy. Symptoms like fever and pain can continue to be managed with analgesics like paracetamol. WHO also recommends against use of a new antiviral (VV116) for patients, except in clinical trials. The update also includes a strong recommendation against the use of ivermectin for patients with non-severe COVID-19. WHO continues to advise that in patients with severe or critical COVID-19, ivermectin should only be used in clinical trials. more

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Relevance of CBR and Inclusive Development in Post 2015 Agenda

Thomas, M. and Ninomiya, A. CBR Asia-Pacific Network (2015) C1

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Health interventions for older people in emergencies

Fritsch, P. Help Age International; ECHO (2013) CC

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Essential Competencies for Basic Midwifery Practice

International Confederation of Midwives (2010)

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Handbook for Emergencies

UNHCR (2007) C2

Section One summarizes UNHCR’s mandate of international protecdtion and the aim and principles of emergency response; Section Two deals with emergency management; Section Three covers the vital sectors and problem areas in refugee emergencies, including health, food, sanitation and water, a... more

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Pandemic influenza preparedness and response WHO guidance document

World Health Organization (2009)

This document should be used in conjunction with the WHO checklist for influenza preparedness planning published by the World Health Organization in 2005. Available in English; Chinese; French

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No Protection, No Respect

Safeguarding Health in Conflict Coalition (2016) CC

Health Workers and Health Facilities under Attack 2015, and Early 2016

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Philippines: 2014 Global AIDS Response Progress Reporting

UNAIDS (2014) C1

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The HIV response in emergencies

Ruth Ayarza, Sophie Baver; Marie Mercy Zevallos, et al. International HIVAIDS Alliance; POZ (2014)

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EMPowerment for Advocacy - The EMPAD Policy Framework for national advocacy by and with key populations

E. Restoy; A. Teltschik; K. Safreed-Harmon; et al. International HIVAIDS Alliance (2014) C2

Policy Framework

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Emergency in Ukraine: external situation report
recommended

World Health Organization WHO (2022) C_WHO

Here you can download the latest Situation Reports Weekly updates on the current situation in Ukraine and refugee-receiving countries, priority public health concerns and WHO’s actions to rapidly respond to the health emergency triggered by the conflict and to minimize disruptions to the delivery... more

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Scaling Up Nutrition - a Framework for Action

Standing committee on Nutrition SCN, et al. (2008)

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Assistance to Victims of Landmines and Explosive Remnants of War: Guidance on Child-focused Victim Assistance. Chapter 1-4

UN Children's Fund UNICEF (2014)

This document is one of eight PDF documents that comprise the Guidance on Child-focused Victim Assistance. All are available in PDF at . The full document is also available. This first section contains the Acknowledgements, Foreword, Acronyms and Chapters 1 th... more

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Rwanda HIV and AIDS National Strategic Plan (July 2013 - June 2018)

Ministry of Health, Rwanda & Rwanda Biomedical Centre (2013) C2

During the implementation of the National Strategic Plan 2009–2012 on HIV and AIDS, Rwanda has continued its progress towards universal access to HIV and AIDS services. The new HIV and AIDS National Strategic Plan July 2013–June 2018 (thereafter referred to as ‘the NSP’) presented here is se... more

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Data for impact_ How UNADIS data is guiding the world to end AIDS

UNAIDS (2022) C_WHO

As part of the UN’s data strategy—which seeks to nurture data as a strategic asset for insight, impact and integrity—UNAIDS plays an indispensable role in generating data for effective action against the AIDS pandemic. It leads the world’s most extensive data collection on HIV epidemiology,... more

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HIV and universal health coverage

UNAIDS UNAIDS (2020) C2

A guide for civil society Accessed: 30.01.2020

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COVID-19: A catastrophe for children in sub-Saharan Africa

UN Children's Fund UNICEF (2020) C_UNICEF

The well-being of children in sub-Saharan Africa is under siege from all directions since the advent of the COVID-19 pandemic. The region is now suffering its first-ever economic recession, pushing about 50 million people into extreme poverty, a majority of whom are children.