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Mpox Testing Strategy - November 2024

Africa Center for Disease Control and Prevention (2024) CC

Mpox is an emerging zoonotic disease caused by the mpox virus, a member of the Orthopoxvirus genus closely related to the variola virus that causes smallpox. Mpox was first discovered in 1958 when outbreaks of a pox-like disease occurred in monkeys kept for research. The first human case was recorde...d in 1970 in the Democratic Republic of the Congo (DRC) during a period of intensified effort to eliminate smallpox and since then the infection has been reported in a number of African countries. Mpox can spread in humans through close contact, usually skin-to-skin contact, including sexual contact, with an infected person or animal, as well as with materials contaminated with the virus such as clothing, beddings and towels, and respiratory droplets in prolonged face to face contact. People remain infectious from the onset of symptoms until all the lesions have scabbed and healed. The virus may spread from infected animals through handling infected meat or through bites or scratches. Diagnosis is confirmed by polymerase chain reaction (PCR) testing of material from a lesion for the virus’s DNA. Two separate clades of the mpox virus are currently circulating in Africa: Clade I, which includes subclades Ia and Ib, and Clade II, comprising subclades IIa and IIb. Clade Ia and Clade Ib have been associated with ongoing human-to-human transmission and are presently responsible for outbreaks in the Democratic Republic of the Congo (DRC), while Clade Ib is also contributing to outbreaks in Burundi and other countries. In 2022‒2023 mpox caused a global outbreak in over 110 countries, most of which had no previous history of the disease, primarily driven by human-to-human transmission of clade II through sexual contact. In just over a year, over 90,000 cases and 150 deaths were reported to the WHO. For the second time since 2022, mpox has been declared a global health emergency as the virus spreads rapidly across the African continent. On 13 Aug 2024, Africa CDC declared the ongoing mpox outbreak a Public Health Emergency of Continental Security (PHECS), marking the first such declaration by the agency since its inception in 2017.7 This declaration empowered the Africa CDC to lead and coordinate responses to the mpox outbreak across affected African countries. On August 14, 2024, the WHO declared the resurgence of mpox a Public Health Emergency of International Concern (PHEIC) emphasizing the need for coordinated international response. As of August 2024, Mpox has expanded beyond its traditional endemic regions, with new cases reported in countries including Sweden, Thailand, the Philippines, and Pakistan. Sweden has confirmed its first case of Clade 1 variant, which has been rapidly spreading in Africa, particularly in DRC. The emergence of this new variant raises concerns about its potential for higher lethality and transmission rates outside Africa. more

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Impact of health systems strengthening on coverage of maternal health services in Rwanda, 2000–2010: a systematic review

Maurice Bucagu, Jean M. Kagubare, Paulin Basinga, Fidèle Ngabo, Barbara K Timmons & Angela C Lee Reproductive Health Matters (2012) CC

From 2000 to 2010, Rwanda implemented comprehensive health sector reforms to strengthen the public health system, with the aim of reducing maternal and newborn deaths in line with Millennium Development Goal 5, among many other improvements in national health. Based on a systematic review of the lit... more

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Multi-Sector Nutrition Education and Communication Strategy (NECS) II 2021-2025

Government of Malawi; Department of Nutrition; HIV and AIDS Ministry of Health (2021) CC2

The Department of Nutrition, HIV and AIDS (DNHA) in Ministry of Health and Population is grateful to all stakeholders who contributed to the development of the Nutrition Education Communication Strategy II. The DNHA acknowledges the financial and technical support from the World Bank and USAID throu... more

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Orientations sur la sécurité biologique en laboratoire en rapport avec la maladie à coronavirus 2019 (‎‎COVID-19)
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Organisation Mondiale de la Santé OMS (2021) C_WHO

‎‎Orientations provisoires, 28 janvier 2021 Dans cette version mise à jour des orientations sur la sécurité biologique en laboratoire en rapport avec le SARS-CoV-2, le virus responsable de la maladie à coronavirus 2019 (COVID-19), les points suivants ont été ajoutés : aspects de... more

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South African MATERNAL, PERINATAL, and NEONATAL Health Policy

National Department of Health (NDoH) South Africa NDoH South Africa (2021) CC

As a lower-middle-income country (LMIC), South Africa (SA) bears the burden of maternal and neonatal mortality similar to other sub- Saharan African countries. According to the Saving Mothers Report 2017/19, there has been a progressive and sustained reduction in institutional maternal mortality... more

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Diagnostic methods for the control of strongyloidiasis, Virtual meeting, 29 September 2020

World Health Organization WHO (2021) C_WHO

23 March 2021 The meeting addressed the last key area, that is, determining the best method or combination of diagnostic methods for a control programme for S. stercoralis infections in humans. Dr Montresor’s presentation highlighted that while there is currently no “gold standard” for the... more

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Praziquantel for the treatment of schistosomiasis during human pregnancy

Friedman, J.F. et al. (2018) CC

In 2014, an estimated 40 million women of reproductive age were infected with Schistosoma haematobium, S. japonicum and/or S. mansoni. In both 2003 and 2006, the World Health Organization (WHO) recommended that all schistosome-infected pregnant and breastfeeding women be offered treatment, with praz... more

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Special Issue: Newborn Health in Uganda

Kate Kerber, Stefan Peterson & Peter Waiswa Global Health Action (2015)

This special issue on Newborn Health in Global Health Action is being launched to share the experience of how to scale up a cost-effective package of newborn care that involves families, community health workers and health facilities. The results of this community randomized trial, the Uganda Newbor... more

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The Ukraine war and threats to food and energy security

Benton, T.; et al. Chatham House (2022) CC

Cascading risks from rising prices and supply disruptions, April 2022. Global resource markets are still reeling from the impacts of Russia’s invasion of Ukraine; the two countries are major suppliers of energy, food and fertilizers. Supply disruption and the sudden imposition, in response to the... more

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A systematic examination of international funding flows for Ebola virus and Zika virus outbreaks 2014-2019: donors, recipients and funding purposes

Quirk, E.J.; A. Gheorghe; K. Hauck BMJ Global Health (2021) C1

There has been no systematic comparison of how the policy response to past infectious disease outbreaks and epidemics was funded. This study aims to collate and analyse funding for the Ebola epidemic and Zika outbreak between 2014 and 2019 in order to understand the shortcomings in funding reporting... more

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L'ulcère de buruli : reconnaître et agir : un manuel pour le personnel de santé

Organisation Mondiale de la Santé OMS (2011) C_WHO

/// ULCÈRE DE BURULIIV Les objectifs de ce document sont de contribuer à ce que l’ulcère de Buruli (infection à Mycobacterium ulcerans) soit mieux reconnu et d’inciter à intensifier les efforts pour détecter les cas à un stade précoce de l’infection. Aujourd’hui, les malades peuvent... more

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Spiritual Care Education of Health Care Professionals

Baldacchino, D. University of Malta (2015) CC

The International Council of Nurses (ICN) Code of Ethics ([1], p. 5) specifies the nurse’s role of promoting “an environment in which the human rights, values, customs and spiritual beliefs of the individual, family and community are respected”. The Malta Code of Ethics supports this for nurse... more

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Liste Nationale des Médicaments et autres produits de Santé Essentiels 2022 du Tchad

World Health Organisation (WHO) (2023) C_WHO

Les médicaments ont été classés à la fois par classe pharmaco-thérapeutique et par ordre alphabétique. La présence d’une marque astérisque renvoie à davantage de précision pour le (les) médicament(s) concerné(s).

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Banking on health: the surging pandemic of health financialization

Dentico N. Society for International Development (SID) (2023) CC

In the last three decades, health financialization has surged in several creative ways, yet this growing phenomenon remains surprisingly unknown, and neglected, in the global health arena. Financialization in the health domain could be described as the uncontrolled expansion of finance along vari... more

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Financing for Sustainable Development Report 2024

Inter-agency Task Force on Financing for Development United Nations (UN) (2024) CC

The world is facing a sustainable development crisis. The 2024 Financing for Sustainable Development Report: Financing for Development at a Crossroads finds that financing challenges are at the heart of the crisis and imperil the SDGs and climate action. The window to rescue the SDGs and prevent a c... more

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Stratégie Nationale de Plaidoyer et Mobilisation des Ressources en Faveur de Lutte Contre le Paludisme 2024–2028

Programme National de Lutte contre le Paludisme (PNLP), République Démocratique du Congo Ministère de la Santé Publique, Hygiène et Prévention, République Démocratique du Congo, avec l’appui de Breakthrough ACTION-RDC et USAID (2023) C2

La Stratégie Nationale de Plaidoyer et de Mobilisation des Ressources en faveur de la Lutte contre le Paludisme 2024–2028 en République Démocratique du Congo vise à renforcer l’engagement politique, mobiliser des financements domestiques et internationaux et impliquer tous les secteurs (publ... more

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Determinants of Maternal Care-Seeking in Kenya

Samwel Mbugua, Kerry L. D. MacQuarrie (2018) C1

DHS Further Analysis Reports No. 111
This study is a theory-driven analysis of the socio-demographic determinants of maternal care seeking in Kenya. Specifically, it examines predisposing, enabling, and need factors potentially associated with use of antenatal care (ANC), health facility delive... more

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Manual clínico: atención integral de salud en situaciones de violencias por motivos de género. Herramientas para equipos de salud

Pan American Health Organization (PAHO) (2022) C_WHO

Las violencias por motivos de género atraviesan a mujeres, LGBTI+, niñeces y adolescencias con gran impacto en múltiples dimensiones de la vida y el sistema de salud tiene un rol fundamental en su detección temprana, en la evaluación del riesgo, en la prevención y la atención integral.Por... more

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Lista de medicamentos essenciais para tratamento de pacientes admitidos nas unidades de terapia intensiva com suspeita ou diagnóstico confirmado da COVID-19 (LMEUTI-COVID-19)

Pan American Health Organization (PAHO), OPS (2022) C_WHO

Tercera versión, 1 de febrero del 2022. Estas orientaciones tienen por objetivo contribuir a que los sistemas de salud prioricen los medicamentos esenciales que deben estar disponibles y ser asequibles para manejar los pacientes en las unidades de cuidado intensivos durante las emergencias de salud... more

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Manuel pour la gestion de l’aspect santé publique des accidents chimiques

World Health Organization 2016 (2016) C_WHO

"Le Manuel de l’OMS pour la gestion de l’aspect santé publique des accidents chimiques a pour objet de passer en revue l’ensemble des principes et des rôles qui sont ceux de la santé publique dans la gestion des accidents et des situations d’urgence d’origine chimique. Tout en apportant... more

Orientations sur la sécurité biologique en laboratoire en rapport avec la maladie à coronavirus 2019 (‎‎COVID-19) recommended

Orientations sur la sécurité biologique en laboratoire en rapport avec la maladie à coronavirus 2019 (‎‎COVID-19)
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