Naicker et al. BMC Palliative Care (2016) 15:41 DOI 10.1186/s12904-016-0114-7
Arsenical monotherapies were previously very successful for treating human African trypanosomiasis (HAT).
Melarsoprol resistance emerged as early as the 1970s and was widespread by the late 1990s.
Melarsoprol resistance represents the only example of widespread drug resistance in HAT patients wher...e the genetic mechanism has been established.
The current goal of elimination of HAT as a public health problem by 2020 may be undermined by the emergence and spread of resistance to current or new drugs.
Insights into potential resistance mechanisms for current and new drugs will facilitate predictions of the likelihood of resistance and will also facilitate rational approaches to minimizing, monitoring, and tackling the future emergence of resistance.
more
These guidelines have been developed specifically to address ethical issues of conducting research in children.
BMJ 2009; 338 doi: https://doi.org/10.1136/bmj.b158 (Published 05 February 2009)
Cite this as: BMJ 2009;338:b158
Correspondence to: A Burns alistair.burns@manchester.ac.uk
This Manual is primarily intended for Local Government, Community Based Organizations and Civil Society Organizations (CSO) supporting or implementing Community Based Disaster Risk Management (CBDRM) program.
The World Cities Report 2020 shows that the intrinsic value of sustainable urbanization can and should be harnessed for the wellbeing of all. The Report provides evidence and policy analysis of the value of urbanization from an economic, social and environmental perspective, including the unquantifi...able value that gives cities their unique character; and also explores the role of innovation and technology, local governments, targeted investments and the effective implementation of the New Urban Agenda in fostering the value of sustainable urbanization.
Please download the whole report in different languages here: https://reliefweb.int/report/world/world-cities-report-2020-value-sustainable-urbanization
more
Rev Mex Patol Clin Med Lab 2020; 67 (2): 93-112: La tuberculosis (TB) es en la actualidad la patología de tipo infeccioso que causa mayor número de muertes alrededor del mundo cada año. La percepción acerca de esta entidad ha cambiado a lo largo del tiempo, ya que se consideraba que se relaciona...ba con la pobreza y las consecuencias de la misma como desnutrición, hacinamiento y promiscuidad; sin embargo, en los últimos 40 años con la aparición de la infección del virus de la inmunodeficiencia humana (VIH) los casos comenzaron a incrementarse, además de la aparición de nuevas sepas multirresistentes a la terapéutica convencional, lo que indudablemente ha provocado la reemergencia de esta entidad así como la potencialización en su letalidad.
more
This flipbook is for community health workers to use to educate their communities about Zika, how it is spread, the effects of the virus, what to do if infected, and how to prevent Zika.
Key findings from a February 2021 survey from the Partnership for Evidence-Based Response to COVID-19 (PERC)