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Publication Years
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2723
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Category
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Toolboxes
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1
Heart failure with a reduced ejection fraction (HFrEF) is a condition frequently encountered by healthcare professionals and, in order to achieve the best outcomes for patients, needs to be managed optimally. This guideline document is based on the
...
European Society of Cardiology Guidelines for the treatment of acute and chronic heart failure published in 2016, and summarises what is considered the best current management of patients with the condition. It provides information on the definition, diagnosis and epidemiology of HFrEF in the African context. The best evidence-based treatments for HFrEF are discussed, including established therapies (beta-blockers, ACE-i/ARBs, mineralocorticoid receptor antagonists (MRAs), diuretics) that form the cornerstone of heart failure management as well as therapies that have only recently entered clinical use (angiotensin receptor-neprilysin inhibitor (ARNI), sodium/glucose cotransporter-2 (SGLT2) inhibitors). Guidance is offered in terms of more invasive therapies (revascularisation, implantable cardioverter defibrillators (ICDs) and cardiac resynchronisation therapy (CRT) by implantation of a biventricular pacemaker with (CRT-D) or without (CRT-P) an ICD, left ventricular assist device (LVAD) use and heart transplantation) in order to ensure efficient use of these expensive treatment modalities in a resourcelimited environment. Furthermore, additional therapies (digoxin, hydralazine and nitrates, ivabradine, iron supplementation) are discussed and advice is provided on general preventive strategies (vaccinations). Sections to discuss conditions that are particularly prevalent in sub-Saharan Africa (HIV-associated cardiomyopathy (CMO), peripartum CMO, rheumatic heart disease, atrial fibrillation) have been added to further improve clinical care for these commonly encountered disease processes.
more
First published in 2020, this toolkit is intended for clinicians working in acute care, managing adult and paediatric patients with acute respiratory infection, including severe pneumonia, acute respiratory distress syndrome, sepsis
...
and septic shock. The main objective is to provide key tools for use in the care of critically ill patients – from hospital entry to hospital discharge.
The 2022 updated version includes new tools and adapted algorithms, checklists, memory aids for COVID-19 and influenza, and the latest clinical evidence regarding clinical management of SARI. It is intended to help clinicians care for SARI patients: from epidemiology of severe acute respiratory infections, screening and triage, infection prevention and control, monitoring of patients, laboratory diagnosis, principles of oxygen therapy and different types of ventilation (invasive and non-invasive), as well as antimicrobial and immunomodulator therapies, to ethical and quality of care assessments.
The first edition is availbel in Ukrainian and Russian
more
Os sistemas de saúde estão enfrentando um rápido aumento na demanda gerada pelo surto da COVID-19. Quando os sistemas de saúde ficam sobrecarregados, há um aumento drástico na mortalidade direta causada por um surto e também na mortalidade indireta por doenças imunopreveníveis e por aquelas
...
doenças que possuem tratamento. Análises do surto de ebola em 2014-2015 sugerem que o aumento no número de óbitos causados por sarampo, malária, HIV/AIDS e tuberculose atribuíveis a falhas no sistema de saúde ultrapassou o número de óbitos causados pelo ebola. A capacidade de um sistema de manter a prestação de serviços essenciais de saúde dependerá de sua capacidade inicial e da carga da doença e do contexto de transmissão do vírus COVID-19 (classificado como nenhum caso, transmissão esporádica, em clusters ou comunitária). Manter a confiança da população na capacidade do sistema de saúde de atender, com segurança, as necessidades essenciais e de controlar o risco de infecção nas unidades de saúde é fundamental para garantir que as pessoas continuem a buscar atendimento quando necessário e que sigam as orientações de saúde pública.
more
Aide Memoire. O foco desta nota são as implicações da orientação atual da OMS sobre o uso máscaras cirúrgicas e não cirúrgicas/ de tecido durante a pandemia de COVID-19 para trabalhadores da saúde e trabalhadores que não são da área da saúde, mas que estão envolvidos em atividades ass
...
istenciais comunitárias, especialmente as de combate à malária, doenças tropicais negligenciadas (DTN), tuberculose (TB), infecção pelo vírus da imunodeficiência humana/síndrome da imunodeficiência adquirida (HIV/ AIDS) e doenças imunopreveníveis (VPDs). O uso de máscaras deve ser sempre acompanhado de outras medidas de prevenção e controle de infecção (PCI), como o distanciamento físico de pelo menos 1 metro, a higiene das mãos, evitar tocar o rosto e a etiqueta respiratória usando o cotovelo dobrado sempre que tossir ou espirrar. A limitação da permanência em locais com aglomeração ou espaços fechados, a garantia da ventilação adequada dos ambientes internos e fechados (6), e a limpeza regular das superfícies de alto contato também são medidas de precaução importantes a serem seguidas.
more
National Policy
Internal Document
This document is itended as a quick guide of healtcare workers involved in clincial management
IAS–USA Topics in Antiviral Medicine. September 22, 2025
Desktop Job Aid
39th African Union (AU) Summit, Addis Ababa, Ethiopia, February 2026
Why we need Targets for 2025.
1.2020 Fast Track targets will soon elapse; 2. Current UNAIDS strategy concludes in 2021; 3. Informs possible UN General Assembly Special Session on AIDS in 2021; where a new Political Declaration on
...
AIDS would be adopted; 4. Informs the strategies of other organisations (Global Fund, PEPFAR); . An updated set of programmatic targets for 2025 in needed to keep us on
track for 2030
more
SOP number SOP000108/2020
An unprecedented amount of money is being pledged and used to fund health research and services throughout the
world. Although estimates are diffi cult to obtain, the 2004 estimate for internationa
...
l health funding was about
US$14 billion, and is rapidly increasing, largely because of the emergence and growth of the Bill & Melinda Gates Foundation (BMGF) and the US Government’s AIDS initiative
more
The primary objective of this book is to provide practical, up-to-date guidelines for the consulting clinician working with patients with HIV in primary care
ATIC Newsletter, Vol 15, Issue 1,
February 2022.
If baby HIV exposed, do DBS at six weeks or any time the child is seen if still below 12 months. If > 12 months, do HIV antibody test.