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LEPTOSPIROSIS Fact Sheet for Clinicians

Center for Disease Control and Prevention CDC (2018) CC
• Leptospirosis is a disease that is caused by spirochete bacteria in the genus Leptospira. There are 10 pathogenic species, and more than 250 pathogenic serovars. • While leptospirosis occurs worldwide, it is more common in tropical or sub-tropical climates.
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Risk factors of Cholera mortality

Global Task Force On Cholera Control (GTFCC) (2022) CC
To better adapt current case management practices and address excess mortality in otherwise treatable cases will require better knowledge of the demographic characteristics of the patients and comorbidities which can make severe dehydration harder to tolerate physiologically. With this in mind, a ... more
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Considerations for border health and points of entry for mpox: interim guidance

World Health Organisation (WHO) (2024) C_WHO
On 14 August 2024, the Director-General of the World Health Organization determined that the upsurge of mpox in a growing number of countries in Africa constitutes a new public health emergency of international concern (PHEIC) under the International Health Regulations (IHR) (2005)
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Intermittent screening and treatment in pregnancy and the safety of ACTs in the first trimester

World Health Organization WHO (2015) C_WHO
Recommendations
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Adherence to Antiretroviral Therapy in Children and Adolescents With HIV

ClinicalInfo.hiv.gov (2025) C_CDC
Panel Recommendations
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European standards of HIV prevention and care: module on HIV and co-morbidities

European Centre for Disease Prevention and Control ECDC (2025) CC
The standards of care for HIV define the expected or desired quality of prevention, treatment, and care for people at risk of HIV acquisition or living with HIV. The standards are based on a scientific rationale, as well as the responsibilities of each stakeholder, to ensure that people receive app ... more
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Updates on the management of severe acute malnutrition in infants and children
recommended

World Health Organization (2013) C_WHO
This guideline provides global, evidence-informed recommendations on a number of specific issues related to the management of severe acute malnutrition in infants and children, including in the context of HIV.
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Antiretroviral Therapy Guidelines for HIV-Infected Adults and Adolescents Including Post-exposure Prophylaxis

Ministry of Health & Family Welfare Government of India Ministry of Health & Family Welfare Government of India (2007) C1
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Effect of Artesunate–Amodiaquine on Mortality Related to Ebola Virus Disease

Etienne Gignoux, M.P.H., Andrew S. Azman, Ph.D., Martin de Smet, M.D., et al. (2016) C2
New England Journal of Medicine 374:1,pp23-32
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Ghana: GUIDELINES FOR REPORTING ADVERSE REACTION

Food and Drugs Authority (FDA), Ghana (2016) C2
Document No. : FDA/SMC/SMD/GL-RAR/2013/01
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Combined Use of Delamanid and Bedaquiline to Treat Multidrug-Resistant and Extensively Drug-Resistant Tuberculosis: A Systematic Review

G. B. Migliori, E. Pontali, G. Sotgiu, et al. International Journal of Molecular Scienes (2017) C2
Int. J. Mol. Sci. 2017, 18, 341, 1 - 10
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Rwanda: MOH GUIDELINES ON SUBMISSION OF DOCUMENTATION FOR REGISTRATION OF HUMAN PHARMACEUTICAL PRODUCTS

Ministry of Health, Rwanda (2014) C2
These guidelines have been developed to provide guidance to the Ministry of Health in managing applications for registration of human pharmaceutical products in Rwanda. It was compiled by the Technical Working Group (TWG) on Medicines Evaluation and Registration (MER) of the East African Community M ... more
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Use of antibiotics for the treatment and control of cholera
recommended

Global Task Force for Cholera Control (2018) C1
Cholera is an acute diarrhoeal disease caused by the ingestion of food or water contaminated with the bacterium V. cholerae. It has a short incubation period of a few hours to 5 days. It is endemic in some countries, frequently showing seasonal variations in the number of reported cases. Cholera a ... more
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Developmental roadmap for antimicrobial susceptibility testing systems

Belkum, A.van, T. T. Bachmann, G. Lüdke, et al. (2019) CC
Nature Reviews Microbiology Vol. 17 (2019)pp.51-62 Antimicrobial susceptibility testing (AST) technologies help to accelerate the initiation of targeted antimicrobial therapy for patients with infections and could potentially extend the lifespan of current narrow- spectrum antimicrobials. Althoug ... more
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Standard treatment guidelines oncology India

Ministry of Health & Family Welfare, India (2020) C1
Accessed Febr. 6, 2020
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Advice on the use of point-of-care immunodiagnostic tests for COVID-19

OCHA; Reliefweb; World Health Organization (WHO) OCHA; Reliefweb; World Health Organization (WHO); Health Cluster (2020) C2
Scientific brief 8 April 2020
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Guidelines for emergency and compassionate use authorisation of health products and technologies

Ministry of Health, Kenya (2020) CC
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Frequently Asked Questions (FAQs) about COVID-19 Candidate Vaccines and Access Mechanisms. Version 3, 6 January 2021

Pan American Health Organisation PAHO (2021) C_WHO
Will COVID-19 vaccines be safe? Will all the COVID-19 candidate vaccines be successful? What are the different phases a vaccine must go through to be approved? This document provides responses to the most frequently asked questions about candidate vaccines and access to COVID-19 vaccination.
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Interim statement on dose-sparing strategies for COVID-19 vaccines (fractionated vaccine doses)

World Health Organization WHO (2021) C_WHO
7 August 2021
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Interim recommendations for use of the Bharat Biotech BBV152 COVAXIN® vaccine against COVID-19

World Health Organization WHO (2022) C_WHO
These WHO interim recommendations for use of the BBV152 COVAXIN vaccine were developed on the basis of advice issued by the Strategic Advisory Group of Experts on Immunization (SAGE) and the evidence summary included in the background document and annexes referenced below. This document has been ... more