Antimicrobial resistance (AMR) is a threat to global health and development and it contributes to millions of deaths worldwide each year. Inappropriate use and overuse of antibiotics are driving an increase in AMR and have a detrimental impact on the effectiveness of these critical medicines. Throug...h the Global Action Plan on AMR, WHO is working to improve the surveillance of antimicrobial resistance and reduce inappropriate antibiotic consumption.
There is a recognized need for high-quality resources to improve antibiotic prescribing globally. To address this need, a pragmatic approach was taken by WHO to develop actionable guidance for empiric antibiotic use.
The WHO AWaRe (Access, Watch, Reserve) antibiotic book provides concise, evidence-based guidance on the choice of antibiotic, dose, route of administration, and duration of treatment for more than 30 of the most common clinical infections in children and adults in both primary health care and hospital settings. The information included in the book supports the recommendations for antibiotics listed on the WHO Model Lists of Essential Medicines and Essential Medicines Children and the WHO AWaRe classification of antibiotics.
The WHO AWaRe antibiotic book is accompanied by summary infographics for each infection for both adults and children that provide a quick-reference guide for health care workers at the point of care.
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Lancet 2013; 381: 1405–16
Series: Childhood Pneumonia and Diarrhoea no.1
Technical Note
Recently, the approach to hazardous events has undergone a considerable shift, away from reactive activities focused on managing and responding to events and towards a more proactive process of emergency and disaster risk management (DRM). The ultimate goal of this shift in focus is ...to prevent new and reduce existing disaster risks, a process known as disaster risk reduction (DRR), while strengthening individual, community, societal and global resilience.
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This rapid advice guide examines the evidence and makes recommendations for the use of chest imaging in acute care of adult patients with suspected, probable or confirmed COVID-19. Imaging modalities considered are radiography, computed tomography and ultrasound. This guide addresses the care pathwa...y from presentation of the patient to a health facility to patient discharge. It considers different levels of disease severity, from asymptomatic individuals to critically ill patients. Accounting for variations in the benefits and harms of chest imaging in different situations, remarks are provided to describe the circumstances under which each recommendation would benefit patients. The guide also includes implementation considerations for different settings, provides suggestions for impact monitoring and evaluation and identifies knowledge gaps meriting further research.
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THE REPUBLIC OF BOTSWANA | MINISTRY OF HEALTH | DEPARTMENT OF PUBLIC HEALTH | NATIONAL MALARIA CONTROL PROGRAMME
This report investigates the impact of potential misclassification of samples on HIV prevalence estimates for 23 surveys conducted from 2010-2014. In addition to visual inspection of laboratory results, we examined how accounting for potential misclassification of HIV status through Bayesian latent ...class models affected the prevalence estimates. Two types of Bayesian models were specified: a model that only uses the individual dichotomous test results and a continuous model that uses the quantitative information of the EIA (i.e., the signal-to-cutoff values). Overall, we found that adjusted prevalence estimates matched the surveys’ original results, with overlapping uncertainty intervals. This suggested that misclassification of HIV status should not affect the prevalence estimates in most surveys. However, our analyses suggested that two surveys may be problematic. The prevalence could have been overestimated in the Uganda AIDS Indicator Survey 2011 and the Zambia Demographic and Health Survey 2013-14, although the magnitude of overestimation remains difficult to ascertain. Interpreting results from the Uganda survey is difficult because of the lack of internal quality control and potential violation of the multivariate normality assumption of the continuous Bayesian latent class model. In conclusion, despite the limitations of our latent class models, our analyses suggest that prevalence estimates from most of the surveys reviewed are not affected by sample misclassification.
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The report studied child poverty in nine dimensions – development/stunting, nutrition, health, water, sanitation, and housing. Other dimensions included education, health related knowledge, and information and participation.
An estimated 36 million of a total population of 41 million children und...er the age of 18 in Ethiopia are multi-dimensionally poor, meaning they are deprived of basic goods and services in at least three dimensions
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Executive summary of case studies in 10 hospitals and 10 Health Centers in 10 Districts with targets indicators year of 2016 in preparing for disaster preparedness in Indonesia
(The Pyidaungsu Hluttaw Law No. 21,2013)
The use of Delamanid and Bedaquiline for Children with Drug-Resistant Tuberculosis.
Версия: 2
Дата: 10 февраля 2020 г.
Протокол посвящен выявлению и отслеживанию пациентов и их близких контактов в общей массе населения либо в условиях локального рас...ространения (например, в домохозяйствах, медицинских, образовательных учреждениях). FFX - основной протокол исследования, который должен быть использован при выявлении первоначальных лабораторно подтвержденных случаев COVID-19 в стране.
Для более целенаправленного подхода к конкретным группам и более точной оценки эпидемиологических параметров доступны три других протокола исследований
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The Panel recommendations on initial combination regimens for the antiretroviral therapy (ART)-naive, HIV-infected patients.
Training for staff working at DR-TB management centres.
Training modules