Arsenical monotherapies were previously very successful for treating human African trypanosomiasis (HAT).
Melarsoprol resistance emerged as early as the 1970s and was widespread by the late 1990s.
Melarsoprol resistance represents the only example of widespread drug resistance in HAT patients wher...e the genetic mechanism has been established.
The current goal of elimination of HAT as a public health problem by 2020 may be undermined by the emergence and spread of resistance to current or new drugs.
Insights into potential resistance mechanisms for current and new drugs will facilitate predictions of the likelihood of resistance and will also facilitate rational approaches to minimizing, monitoring, and tackling the future emergence of resistance.
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The Anglophone Africa Civil Society and Communities CCM Shadow Report and Scorecard Initiative
Celebrating ten years of success 2004-2014
Treating the Patient with Tuberculosis
The World Health Organization Disability Assessment Schedule (WHODAS 2.0) is a generic assessment instrument developed by WHO to provide a standardized method for measuring health and disability across cultures. It was developed from a comprehensive set of International Classification of Functioning..., Disability and Health (ICF) items that are sufficiently reliable and sensitive to measure the difference made by a given intervention.
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Техническая записка;
Целью настоящей Технической записки является оказание содействия кандидатам наполучение грантов Глобального фонда при рассмотрении ...возможностей включения программ, направленных на устранение барьеров, обусловленных нарушением прав человека и гендерным неравенством, которые препятствуют получению услуг по профилактике, диагностике и лечению туберкулеза (ТБ), в запросы на финансирование, а также оказание помощивсем заинтересованным сторонам в том, чтобы программы по борьбе с ТБ обеспечивали продвижение и защиту прав человека и гендерного равенства.
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Second Edition
AIDS Medicines and diagnostics services
July 2015
(For enhanced adherence counseling [EAC] and second-line ART consideration)
Regional situation analysis, practices, experiences, lessons learned and ways forward.