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Newborn survival in Nepal: a decade of change and future implications

Pradhan, Y.V., Upreti, S.R., Pratap, K.C.N, et al. Health Policy and Planning (2012) CC

Nepal is on target to meet the Millennium Development Goals for maternal and child health despite high levels of poverty, poor infrastructure, difficult terrain and recent conflict. Each year, nearly 35000 Nepali children die before their fifth birthday, with almost two-thirds of these deaths occurr... more

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Prevalence of drug-resistant tuberculosis in Nigeria: A systematic review and metaanalysis

C. C. Onyedum, I. Alobu, K. N. Ukwaja PLOS One; O. Neyrolles (Institut de Pharmacologie et de Biologoie Structurale) (2017) CC

PLoS ONE 12(7): e0180996. https://doi.org/10.1371/journal.pone.0180996

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Counterfeit drugs and medical devices in developing countries

Beverly D Glass (2014) CC

The occurrence of a high percentage of couterfeit medicines on the global medicines market is often attributed to a lack of effective regulation and a weak enforcement capacity. This review, while focusing on counterfeit medicines and medical devices in developing countries, will present information... more

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Global Assessment of Schistosomiasis Control Over the Past Century Shows Targeting the Snail Intermediate Host Works Best

Sokolow SH, CL Wood, IJ Jones, et al. (2016) CC

PLoS Negl Trop Dis 10(7): e0004794. doi:10.1371/journal.pntd.0004794

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Serious adverse events following treatment of visceral leishmaniasis: A systematic review and meta-analysis

Singh-Phulgenda, S., Dahal, P., Ngu, R. et al. PLOS Neglected Tropical Diseases (2021) C1

Despite a historical association with poor tolerability, a comprehensive review on safety of antileishmanial chemotherapies is lacking. We carried out an update of a previous systematic review of all published clinical trials in visceral leishmaniasis (VL) from 1980 to 2019 to document any reported ... more

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Diagnosis disclosure to adolescents living with HIV in rural Kenya improves antiretroviral therapy adherence and immunologic outcomes: A retrospective cohort study

G. J. Montalto; Fredrick K. Sawe; A. Miruka; et al. Plos One (2017) CC

PLOS ONE | https://doi.org/10.1371/journal.pone.0183180 October 9, 2017

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Opting out of the growth society?

Kommission Weltkirche der Deutschen Bischofskonferenz (2018) C2

Studien der Sachverständigengruppe „Weltwirtschaft und Sozialethik“ Nr. 21 On the basis of a reflection on social ethics, the German Bishops’ Conference expert panel on "Global Economy and Social Ethics" has analyzed the role of economic growth in relation to environmental issues and sustain... more

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A Global Perspective on Pyrazinamide Resistance: Systematic Review and Meta- Analysis

M. G. Whitfield, H. M. Soeters, R. M. Warren, et al. PLOS One; I. Mokrousov, (St. Petersburg Pasteur Institute) (2015) CC

PLOS ONE | DOI:10.1371/journal.pone.0133869 July 28, 2015, p.1-16

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The perception of disability by community groups: Stories of local understanding, beliefs and challenges in a rural part of Kenya

Bunning K, Gona JK, Newton CR, Hartley S PLoS ONE (2017) CC

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How socio-ecological transformation can succeed.

German's Bishop Conference Commission on International Church Affairs (2022) C2

An interdisciplinary study within the framework of the dialogue project on the contribution of the Catholic Church to a socio-ecological transformation. The study examines the obstacles to the implementation of the socio-ecological transformation and develops recommendations for action.

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Prevalence of Pulmonary Tuberculosis among Prison Inmates in Ethiopia, a Cross-Sectional Study

S. Ali, A. Haileamlak, A. Wieser, et al. (2015) CC

PLOS ONE 10(12): e0144040. doi:10.1371/journal.pone.0144040

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Integrating the Water Planetary Boundary With Water Management From Local to Global Scales

Zipper, S.; et al. (2020) CC

February 2020Earth's Future 8(2):e2019EF001377.The water planetary boundary attempts to provide a global limit to anthropogenic water cycle modifications, but it has been challenging to translate and apply it to the regional and local scales at which water problems and management typically occur. We... more

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Potential Risk of Dengue and Chikungunya Outbreaks in Northern Italy Based on a Population Model of Aedes albopictus (Diptera: Culicidae)

Giorgio Guzzetta, Fabrizio Montarsi, Frédéric Alexandre Baldacchino et al. (2016) CC

PLoS Neglected Tropical Diseases https://doi.org/10.1371/journal.pntd.0004762 This study shows the importance of an integrated entomological and medical surveillance for the evaluation of arboviral disease risk, which is a precondition for designing cost-effective vector control programs.

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Government policy interventions to reduce human antimicrobial use: A systematic review and evidence map

Van Katwyk, S. R.; Grimshaw, J. M.; et al (2019) C2

BACKGROUND: Growing political attention to antimicrobial resistance (AMR) offers a rare opportunity for achieving meaningful action. Many governments have developed national AMR action plans, but most have not yet implemented policy interventions to reduce antimicrobial overuse. A systematic evidenc...e map can support governments in making evidence-informed decisions about implementing programs to reduce AMR, by identifying, describing, and assessing the full range of evaluated government policy options to reduce antimicrobial use in humans. METHODS AND FINDINGS: Seven databases were searched from inception to January 28, 2019, (MEDLINE, CINAHL, EMBASE, PAIS Index, Cochrane Central Register of Controlled Trials, Web of Science, and PubMed). We identified studies that (1) clearly described a government policy intervention aimed at reducing human antimicrobial use, and (2) applied a quantitative design to measure the impact. We found 69 unique evaluations of government policy interventions carried out across 4 of the 6 WHO regions. These evaluations included randomized controlled trials (n = 4), non-randomized controlled trials (n = 3), controlled before-and-after designs (n = 7), interrupted time series designs (n = 25), uncontrolled before-and-after designs (n = 18), descriptive designs (n = 10), and cohort designs (n = 2). From these we identified 17 unique policy options for governments to reduce the human use of antimicrobials. Many studies evaluated public awareness campaigns (n = 17) and antimicrobial guidelines (n = 13); however, others offered different policy options such as professional regulation, restricted reimbursement, pay for performance, and prescription requirements. Identifying these policies can inform the development of future policies and evaluations in different contexts and health systems. Limitations of our study include the possible omission of unpublished initiatives, and that policies not evaluated with respect to antimicrobial use have not been captured in this review. CONCLUSIONS: To our knowledge this is the first study to provide policy makers with synthesized evidence on specific government policy interventions addressing AMR. In the future, governments should ensure that AMR policy interventions are evaluated using rigorous study designs and that study results are published. more

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HIV prevalence and determinants of loss-to- follow-up in adolescents and young adults with tuberculosis in Cape Town

P. Mulongeni; S. Hermans; J. Caldwell; et al. PLOS One (2019) CC

PLOS ONE | https://doi.org/10.1371/journal.pone.0210937 February 5, 2019

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Efficacy and Safety of Pafuramidine versus Pentamidine Maleate for Treatment of First Stage Sleeping Sickness in a Randomized, Comparator-Controlled, International Phase 3 Clinical Trial

Pohlig G, Bernhard SC, Blum J, Burri C, Mpanya A, et al. PLOS Neclected Tropical Diseases (2016) CC

This was a Phase 3, multi-center, randomized, open-label, parallel-group, active control study where 273 male and female patients with first stage Trypanosoma brucei gambiense HAT were treated at six sites: one trypanosomiasis reference center in Angola, one hospital in South Sudan, and four hospita... more

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Health beliefs and health seeking behavior towards lymphatic filariasis morbidity management and disability prevention services in Luangwa District, Zambia: Community and provider perspectives

Maritim, P., A. Silumbwe, J.M. Zulu, et al. (2021) C2

Lymphatic filariasis (LF) infection if untreated results in fluid accumulation in the limbs or breasts (lymphedema) or genitalia (hydrocele) that is painful and causes great discomfort. Morbidity management and disability prevention (MMDP) strategies such as surgery for hydrocele, treatment of acute... more

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Global Morbidity and Mortality of Leptospirosis: A Systematic Review

Costa, F.; Hagan, J.; Calcagno, J. PLoS Neglected Tropical diseases (2015) CC

Leptospirosis, a spirochaetal zoonosis, occurs in diverse epidemiological settings and affects vulnerable populations, such as rural subsistence farmers and urban slum dwellers. Although leptospirosis is a life-threatening disease and recognized as an important cause of pulmonary haemorrhage syndrom... more

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Adherence interventions and outcomes of tuberculosis treatment: A systematic review and meta-analysis of trials and observational studies

Alipanah N, Jarlsberg L et al. (2018) CC

We systematically reviewed Medline as well as the references of published review articles for relevant studies of adherence to multidrug treatment of both drug-susceptible and drug-resistant TB through February 3, 2018. We included randomized controlled trials (RCTs) as well as prospective and retro... more

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Clinical, Virologic, Immunologic Outcomes and Emerging HIV Drug Resistance Patterns in Children and Adolescents in Public ART Care in Zimbabwe

A. T. Makadzange; M. Higgins-Biddle; B. Chimukangara; et al. PLOS One (2015) CC

PLOS ONE | DOI:10.1371/journal.pone.0144057 December 14, 2015