The objective of the study was the validation and implementation of GeneXpert MTB/RIF for routine use in the rapid detection of tuberculosis and sensitivity to rifampicin in clinical samples; for this, 1592 respiratory samples were collected and analyzed in the laboratory of Instituto Nacional de In...vestigación en Salud Pública Guayaquil. The analysis of the results of GeneXpert in comparison with smear microscopy showed an initial sensitivity of 99.8% and specificity of 93.2%; The analysis of discrepancies using the results of the culture as a reference method showed that the GeneXpert results considered false negatives turned out to be true negatives, the same happens with the false positives that correspond to true positives. Recalculated the sensitivity and specificity of the GeneXpert was 99.8% and 100% correspondingly. The comparison with the drugs susceptibility test showed a sensitivity of 91.4% and a specificity of 95.5% for the GeneXpert MTB/RIF system. It is concluded that the implementation of the GeneXpert system allows solution to certain problems associated with the application of conventional diagnostic methodologies, decreasing the waiting times, and increasing the sensitivity and specificity in the diagnosis of drug-resistant tuberculosis, thus generating a valuable opportunity for early diagnosis.
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La Stratégie et plan d’action sur la promotion de la santé dans le contexte des objectifs de développement
durable 2019-2030 cherche à renouveler la promotion de la santé grâce à des interventions de nature sociale,
politique et technique, en agissant sur les déterminants sociaux de la s...anté, à savoir les conditions dans
lesquelles les personnes naissent, grandissent, vivent, travaillent et vieillissent (1). Ils visent à améliorer la
santé et à réduire les iniquités en matière de santé dans le cadre du Programme de développement durable à
l’horizon 2030
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Curr HIV/AIDS Rep. 2022; 19(1): 37–45.
Published online 2022 Jan 29. doi: 10.1007/s11904-021-00589-4.
COVID-19 has had an unprecedented impact on the cascade-of-care among PLWH in LAC. There is a need for
longitudinal studies that assess clinic implication of these pandemic interactions in LAC.
This interim guidance has been updated with advice on safe and appropriate home care for patients with coronavirus disease 2019 (COVID-19) and on the public health measures related to the management of their contacts.
Untersuchung und Dokumentation von Folter und Menschrechtsverletzungen. 2. Auflage
The document, "Sustainable Management of Radiotherapy Facilities and Equipment," by WHO and IAEA, provides guidelines for managing radiotherapy equipment and facilities to ensure effective and safe cancer treatment. It covers essential aspects like preventive and corrective maintenance, funding, inf...rastructure, and staffing requirements for sustainable operation. The document aims to support radiotherapy departments, especially in low-resource settings, by outlining strategies for equipment procurement, maintenance, and replacement, emphasizing safety, quality assurance, and optimal patient care.
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In diesem Bericht untersucht der Unabhängige Experte, inwiefern lesbische, schwule, bisexuelle, transgeschlechtliche und diversgeschlechtliche Menschen nach wie vor durch diskriminierende Rechtsvorschriften und soziokulturelle Normen im Bildungswesen, in der Gesundheits-und W...ohnraumversorgung, in der Arbeitswelt sowie in anderen Bereichen marginalisiert und ausgegrenzt werden. Darüber hinaus betrachtet der Unabhängige Experte das Thema Inklusion und den Zugang zu den entsprechenden Rechten unter dem Aspekt der Intersektionalität und analysiert die verstärkende Diskriminierung, die zu Ausgrenzung und Marginalisierung führt.
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For each medicine the Formulary provides information on use, dosage, adverse effects, contraindications and warnings, supplemented by guidance on selecting the right medicine for a range of conditions
Supplement October 2010
HIV/AIDS, security and conflict: making the connections
Este plan de acción se basa en las necesidades y realidades del Caribe, y describe la estructura y las medidas generales que deben orientar el trabajo a nivel nacional y regional. La ejecución de este plan logrará que la región se ocupe plenamente de los procesos del cambio climático y los acue...rdos mundiales en la materia. Beneficiará a los países y territorios del Caribe al fortalecer sus métodos de cooperación técnica y facilitará el acceso a los recursos humanos, técnicos y financieros necesarios para abordar los efectos de cambio climático sobre la salud.
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Regional Operational Plan 2016 FY17 Strategic Direction Summary
2 May 2016