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1
Взаимосвязь факторов питания и микрофлоры кишечника с развитием депрессивных расстройств (обзор)
А. А. Шульдяков, Ю. Б. Барыльник, Е. П. Ляпина et al.
Saratov Journal of Medical Scientific Research
(2016)
C1
Распространенность депрессивных расстройств и их роль в формировании различных вариантов патологии человека обусловливают актуальность поиска новых подходов к
...
профилактике и лечению депрессий. Перспективным направлением может стать модификация микробиома кишечника. Основанием для разработок в этой области являются приведенные в обзоре данные исследований, подтверждающих значимость состава кишечной флоры в регуляции психических функций, в частности настроения и поведения, роль диеты в развитии депрессий. Обсуждена гипотеза о роли микробиома кишечника в развитии депрессивных расстройств. http://www.ssmj.ru/system/files/2016_02_168-174.pdf
more
Patients with diabetes are at increased risk of developing cardiovascular disease (CVD) with its manifestations of coronary artery disease (CAD), heart failure (HF), atrial fibrillation (AF), and stroke, as well as aortic and peripheral artery diseases. In addition, diabetes is a major risk factor f
...
or developing chronic kidney disease (CKD), which in itself is associated with developing CVD. The combination of diabetes with these cardio-renal comorbidities enhances the risk not only for cardiovascular (CV) events but also for CV and all-cause mortality. The current European Society of Cardiology (ESC) Guidelines on the management of cardiovascular disease in patients with diabetes are designed to guide prevention and management of the manifestations of CVD in patients with diabetes based on data published until end of January 2023. Over the last decade, the results of various large cardiovascular outcome trials (CVOTs) in patients with diabetes at high CV risk with novel glucose- lowering agents, such as sodium–glucose co-transporter-2 (SGLT2) inhibitors and glucagon-like peptide-1 (GLP-1) receptor agonists (RAs), but also novel non-steroidal mineralocorticoid receptor antagonists (MRAs), such as finerenone have substantially expanded available therapeutic op-
tions, leading to numerous evidence-based recommendations for the management of this patient population.
more
Guidelines for the production of extemporaenous formulations and hospital based sterile preparations
In order to streamline and effectively control compounding of medicinal products in hospitals and pharmacies, these Guidelines for Production of Extemporaneous and Hospital Based Sterile Preparations has been crafted. The purpose of these guidelines therefore is to assist pharmacists in
...
discharging their legal and professional obligations to patients in the area of extemporaneous dispensing. This guidance will help to assure the safe and appropriate preparation and supply of extemporaneously prepared medicinal products to patients, where
the supply of such products is necessary.
Extemporaneous and hospital based sterile preparations are critical for patients whose clinical needs cannot be met by registered medicinal products. The guidelines outline the principles and application of the concepts of Good Manufacturing Practice (GMP) requirements for premises, equipment, personnel, storage, quality management system, quality control, compounding processes as well as documentation.
more
В этом дискуссионном документе излагаются факты, касающиеся передозировки опиоидов, мер, которые могут быть приняты в целях предупреждения и лечения (коррекции) п
...
редозировки опиоидов, и указываются области, требующие дальнейшего исследования.
more
Le choléra est une infection diarrhéique aiguë causée par l'ingestion d'eau ou d'aliments contaminés. Ce cours offre une introduction générale au choléra et s'adresse au personnel qui intervient en cas d'apparition de la maladie dans des situations d'urgence complexes ou dans des environneme
...
nts où les infrastructures environnementales de base ont été endommagées ou détruites. Ce cours comprend des documents accessibles en anglais et en arabe. Nous espérons que ce cours vous aidera à vous rappeler de ce que vous savez déjà et à exécuter les bons principes de gestion du choléra.
Objectif d'apprentissage : A la fin de ce cours, les participants devront être en mesure de :
décrire la définition du cas et les alertes pour le choléra ;
décrire les principales voies de transmission ;
identifier les principales actions préventives ; et
expliquer comment le contrôle du choléra est multisectoriel.
Durée du cours : Environ 1 heure.
more
Огляд програм ресоціалізації для споживачів наркотиків серед молоді та підлітків
Євгеній Польщиков, Олександр Красновський, Оксана Панасенко
Київський міжнародний інститут соціології, Державна соціальна служба для сім’ї, дітей та молоді, unicef
(2010)
Опубліковані результати дослідження, проведеного з метою визначення основних проблем, пов’язаних з реабілітацією/ресоціалізацією наркозалежних та можливостю з
...
лучати підлітків 14–17 років до таких програм. Для визначення основних напрямів розвитку центрів реабілітації/ресоціалізації в Україні аналізувався міжнародний досвід країн та їхні підходи до вирішення питань наркоманії; було переглянуто нормативно9правові документи, що стосуються проблем реабілітації і ресоціалізації, а також статистичні дані національного рівня.
more
The purpose of this guide is to provide basic information for Federal disaster responders and other service providers who may be deployed or otherwise assigned to provide or coordinate services in American Indian/Alaska Native (AI/AN) communities.
This guide is intended to serve as a general briefi
...
ng to enhance cultural competence while providing services to AI/AN communities. (Cultural competence is defined as the ability to function effectively in the context of cultural differences.) A more specific orientation or training should be provided by a member of the particular AI/AN community
more
The 2019 edition treating data for 2018 marks sustained international efforts dedicated to reporting on, analysing and understanding the year-to-year variations and long-term trends of a changing climate.
Best practice portal: standards and guidelines
recommended
The Best practice portal is a resource for professionals, policymakers and researchers in the drugs field. We provide information on the available evidence on drug-related prevention, treatment and harm reduction, focusing on the European context. The evidence is compiled following an explicit metho
...
dological process.
more
This document is produced by the Humanitarian Country Team and the United Nations Resident
Coordinator’s Office in Mozambique, with the support of the United Nations Office for the Coordination of
Humanitarian Affairs (OCHA). The projects reflected here support the national government. It covers
...
the
period from November 2018 to June 2019. The Plan has been revised in March 2019 to incorporate the
immediate response to needs arising from the impact of Cyclone Idai.
more
Sexual and gender-based violence (SGBV) threatens displaced women and girls, as well as men and boys, in all regions of the world. Creating safe environments and mitigating the risk of SGBV can only be achieved by addressing gender inequality and discrimination. While the scourge of SGBV is receivin
...
g much more attention internationally – as illustrated by Security Council Resolutions 1820, 1888 and 1960 – preventing SGBV is a complex challenge. To assist operations in addressing this core protection concern, UNHCR is presenting the Action against Sexual- and Gender-Based Violence: An Updated Strategy. This strategy provides a structure to assist UNHCR operations in dealing with SGBV on the basis of a multi-sectoral and interagency approach. UNHCR policies and programmes have for many years helped operations to address SGBV in coordination with other actors. 80% of operations in urban settings and 93% in camp settings work with SGBV Standard Operating Procedures which strengthen cooperation between partners. Moreover, support to community-based organisations has given communities a greater sense of ownership in addressing SGBV.
more
